demethylation是什么意思   demethylation怎么读

demethylation单词基本解析：

demethylation变化用词：

demethylation英英释义：

demethylation中文词源：

demethylation用法和例句：

demethylation

4-N-benzyl demethyl rifampicin

4-N-苄基去甲利福平

In this work, we have examined the role of numerous PCBs as inhibitors of the demethylation of 7-methoxyresorufin, a process that is selectively catalyzed by CYP1A2. 2,3,7,8-Tetrachlorobenzo-p-dioxin (TCDD), 3,3?

CYP1A2可通过影响甲基试卤灵-O-脱甲基酶(methoxyresorufin-O-demethylase,MROD),而选择性地催化7-甲基试卤灵脱甲基反应。

DNA demethylation

DNA去甲基化

DNA demethylation leads to telomere shortening with accelerated aging process in human diploid fibroblasts

DNA去甲基化引起人二倍体成纤维细胞端区缩短并加速衰老进程

DNA methyltransferase inhibitor 5-Aza-CdR can induce demethylation in the promoter region of RASSF1A. It can also reverse epigenetic transcriptional silencing caused by methylation and induce the re-expression of RASSF1A in QBC-939.

DNA甲基转移酶抑制剂5-Aza-CdR能够诱导RASSF1A基因启动子区域去甲基化,并通过该机制诱导RASSF1A基因在人胆管癌细胞系QBC-939中的表达。

Demethylation defect of N-methylglycine

N-甲基甘氨酸脱甲基缺陷

p16 gene demethylation

p16基因去甲基化

An increased tendency for gastric cancer patients with poor prognoses to show SNCG demethylation compared to gastric cancer patients with normal methylation has also been reported.

也有报道,出现SNCG去甲基化的预后不良的胃癌患者比正常甲基化的胃癌患者有增加的趋势。

Keywords 5;6-dihydroxyindole;homoveratronitrile;demethylation;hydroxyl protection;nitration;reductive ring closure;

二羟基吲哚;3;4-二甲氧基苯乙腈;去甲基化;羟基保护;硝化;还原环合;

Benzbromarone was synthesized from salicylaldehyde by condensation with chloroacetone, reduction, acylation, demethylation and bromination with 40.6%overall yield.

以水杨醛为原料，经缩合、还原、酰化、脱甲基、溴化反应制得苯溴马隆，总收率40.6%。

Biochemistry: Ergosterol biosynthesis inhibitor (demethylation inhibitor).Mode of action: Systemic fungicide with protective, curative, and eradicant action.Translocated acropetally within the plant.

作用特点用于叶面喷洒的具有预防、治疗作用的广谱性杀菌剂。

demethyl vancomycin

去甲万古霉素

demethyl coclaurine

去甲乌药碱

demethyl rifampicin

去甲利福平

demethyl psychotrine

去甲吐根亚碱

demethyl cephaeline

去甲土根酚碱

demethyl dione

去甲基二酮

Re-expression of RASSF1A Gene by 5-Aza-CdR-induced Demethylation of the Promoter Region in Human Cholangiocarcinoma Cells

去甲基化修饰诱导人胆管癌细胞中RASSF1A基因表达

5-Aza-CdR may effectively cause demethylation and inhibit the growth of the hepatocarcinoma cell line HepG2 by reactivating the RUNX3 gene transcription silenced by aberrant hypermethylation.

去甲基化制剂5-Aza-CdR能有效地激活肝癌细胞系HepG2因高甲基化所致RUNX3基因沉默的再转录,诱导该基因的表达,从而抑制肿瘤细胞生长。

Reserch on demethylation therapy for hematology malignancy

去甲基化在治疗恶性血液病中的研究

Demethylation could possibly be a new therapy for gastric carcinoma.

去甲基化有望成为胃癌治疗新方法。

Demethyl Tetrandrine

去甲汉防己碱, 去甲粉防己碱

demethyl wedelolactone

去甲蟛蜞菊内酯

It is revealed that the dibenzothiophene demethylation index(DDI) and dibenzothiophene methyl-isomeration index(DMI) could distinguish two types of oils effectively and suffer from little influence of maturity.

发现新参数二苯并噻吩脱甲基指数（DDI）和甲基重排指数（DMI）受成熟度影响小，能有效地区分油源岩岩性。

Transcription and Expression Study of Promoter Region Demethylation on CKIs Genes in Human Colorectal Cancer Cell

启动子区去甲基化对肠癌RKO细胞CKIs基因转录表达的研究

promoter demethylation

启动子脱甲基化

Therefore, we hypothesize that demethylation of these genes occurs during the progressive stages of gastric carcinogenesis, after global DNA hypomethylation.

因此,我们假定:在总DNA低甲基化后,这些基因的去甲基化发生于致胃癌作用的进展期。

The genomic DNA methylation tends to repress gene expression while demethylation or hypomethylation activates the gene expression.

基因组DNA的甲基化修饰通常使基因转录失活,去甲基化或低甲基化则使基因转录活化。

Our results provide evidence for a coupled mechanism of 5-meC demethylation, whereby AID deaminates 5-meC, followed by thymine base excision by Mbd4, promoted by Gadd45.

如果可以的话，它将能导致新的药物来恢复特定基因活性并抑制肿瘤生长。引人注目的是，这一系统也能帮助基因组免遭突变。

Demethyl fumarate

富马酸二甲酯

In this article, the methylation and tumor, methylation and hematologic diseases, methylation detection methods, demethylation therapy in leukemia and so on are reviewed.

本文对甲基化与肿瘤、甲基化与血液病，甲基化的检测方法和去甲基化治疗等问题进行了综述。

Remarkably, overexpression of the deaminase/glycosylase pair AID/Mbd4 in vivo caused demethylation of the bulk genome and injected methylated DNA fragments, likely involving a G:T intermediate.

此次研究发现了2种与DNA去甲基化有关的酶，分别为脱氨基酶和糖基化酶。研究人员表示，这是首次发现明确证据表明，这一酶系统对于维持DNA甲基化平衡起关键作用。

Keywords Chrcmic oxide;alumina;supported catalyst;semiconduction;toluene;demethylation;

氧化铬;氧化铝;负载型催化剂;半导性;甲苯;脱甲基;

biological demethylation of mercury

汞的生物反甲基化

It was found that nickel can be reduced to metal state and demethylation effect of nickel is related to its reduction.

沉积于沸石上的镍在催化裂化反应中能被还原为金属镍，裂化产物中甲烷的生成与金属镍的脱甲基作用相关。

The catalytic activity and demethylation effect of nickel deposited samples is closely related to the method for preparation...

沉积镍沸石经高温水蒸气处理后，裂化产物中的甲烷增多。

Through demethylation the lignin can be made more reactive than phenol itself.

溶于碱溶液的脱甲基木质素与甲醛一起直接加入粘合剂中，热压时，不增加热压时间。

Keywords enamine, diacyl chloride, dehydrogenation, demethylation,flavone, flavone glycoside, deacetylation, flavonol;

烯胺;二元酸二酰氯;脱氢;脱甲基;黄酮;黄酮苷;脱乙酰基;

Keywords Methyl ethers;selective;demethylation reagents;

甲基醚;选择性;去甲基试剂;

Selctive demethylation reagents of methyl ethers

甲基醚的选择性去甲基试剂

Regioselective Demethylation Catalyzed by Methyl Sulfonic Acid

甲磺酸催化的选择性去甲基反应

sterol demethylation inhibitors (DMls)

甾醇脱甲基抑制剂

Objective The aim of the present study was to investigate the influence of CYP2C19 genotypes on plasma concentration and demethylation of amitriptyline in Chinese.

目的探讨中国人的CYP2C19基因型对阿米替林血药浓度及其去甲基代谢的影响。

The results showed that in this process of alkaline hydrolysis the demethylation of poly(methyl glutamate)was faster, but debenzylation of poly(benzyl glutamate) was hardly processed.

研究表明：谷氨酸甲酯均聚物碱解较快，而谷氨酸苄酯均聚物与稀碱在室温下反应很小。

Scientists hae already found out how the methyl groups are attached. The reerse process of demethylation, howeer, has been poorly understood so far.

科学家们已经发现甲基团是如何被黏附的了，但是对逆转的去甲基化过程却知之甚少。

Keywords isoflavones in Trifolium pratense L.;demethylation;metabolism;phytoestrogen;

红三叶草异黄酮;去甲基化;代谢;植物雌激素;

H3-K79 methylation plays a role in DNA repair and transcriptional activation, and the extent and biological significance of histone demethylation will surely attract great attention.

组蛋白H3第79位赖氨酸的甲基化与防止基因失活和DNA修复有关。与此同时，组蛋白的去甲基化也受到更为广泛的关注。

Development of Histone Methylation and Demethylation

组蛋白甲基化和去甲基化研究进展

Evidence for active DNA demethylation in vertebrates is accumulating, but the mechanisms and enzymes remain unclear.

美国科学家近日发现2种特殊酶，它们的偶合能控制关键基因的开关，这些基因会诱发癌症及其它一些疾病。

demethylation reaction

脱甲基反应

methyl demethyl dehydro abietate

脱甲基脱氢枞酸甲酯

demethyl oxalate

草酸二甲酯

Keywords naproxen;microbial transformation;Cunninghamella elegans;O demethylation;LC/MS n;

萘普生;微生物转化;雅致小克银汉霉菌;去甲基化;液相色谱质谱分析;

In a word, the stress during in vitro conservation could induce DNA methylation changes, and the DNA demethylation was relevant to regeneration or differentiation capacity of tested materials.

表明离体保存过程中的各种胁迫能够诱导DNA甲基化变化，其中的脱甲基化可能与愈伤组织或茎尖的再生或分化能力增强有关。

The Study of DNA Methylation and Demethylation on Marek's Disease Virus Genome

马立克氏病毒DNA转录区和非转录区甲基化及脱甲基化的探讨

The reactivity of wheat straw soda lignin(WSSL) can be improved by demethylation modification.

麦草碱木素在碱催化下经脱甲基改性可提高其反应活性。