cyclin单词基本解析：

细胞周期蛋白
n. 细胞周期蛋白
释义细胞周期蛋白；

cyclin变化用词：

cyclin英英释义：

CyclinCyclins are a family of proteins that control the progression of cells through the cell cycle by activating cyclin-dependent kinase (Cdk) enzymes.

以上来源于:Wikipedia

cyclin中文词源：

cyclin用法和例句：

cyclin

Expression of Cyclin D1 in proliferative endometrium and endometrial carcinoma and its significance

1在增生性子宫内膜及子宫内膜癌中的表达及意义

THE EXPRESSION OF CYCLIN D1 IN PLEOMORPHIC ADENOMA AND IN PLEOMORPHIC CARCINOMA OF PAROTID GLAND

1在多形性腺瘤和多形性腺癌中的表达

CDK activation by cyclin binding.

1）CDKs结合cyclin后活化。

The mRNA and protein expressions of cyclin D1 decreased after HCT116 cells were exposed to CAPE for 24, 48 h, which were in a concentration- and time-dependent manner.

2 5、5 0、10mg LCAPE处理HCT116细胞2 4、48h后cyclinD1蛋白和mRNA表达均降低,呈剂量和时间依赖性。

The role of cyclin L2 in apoptosis of hepatocellular carcinoma cell line induced by chemotherapeutical drugs

2在化疗诱导肝癌细胞凋亡中的作用

Construction of human cyclin G2 gene eukaryotic expression recombinant and it's effect on the growth of human gastric carcinoma cell

2表达载体的构建及其对人胃癌细胞生长的作用

Blast analysis showed that HSD45 was identical to INCA1 (Inhibitor of CDK interacting with Cyclin A1), a novel cyclin A1/CDK2 interaction partner in a yeast-triple hybrid approach.

Blast分析发现HSD45与一新基因完全相同。 该基因因能通过与cyclin A1相互作用抑制CDK的活性，故命名为INCAl(Inhibitor of CDK interacting with Cyclin A1)。

Cyclin is the positive regulator which activates CDK and CDK inhibitor (CDKI) is the negative regulator which inactivates CDK.

CDK抑制剂(CDKI)则是负调节因子使CDK失活。

cyclin dependent kinase inhibitors

CDK抑制蛋白

cyclin dependent kinase inhibitor

CK1

Cyclin E was significantly higher expressed in CML than in normal samples (P < 0.001) .

CML患者Cyclin E基因蛋白表达明显高于对照组,有极显著性差异(P<0.001)。

The effect of CyclinE, Cyclin Dl and P21WAF1/CIP1 in CA and their relations to HPV are not clear at present.

Cvciln E、Cyclin D1和p21~(WAF1/CIP1)在尖锐湿疣发生发展中的作用及其与HPV的关系如何，目前尚不清楚。

EXPRESSION AND SIGNIFICANCE OF CYCLIN B_1 AND P34~(cdd2) IN HUMAN NON-SMALL CELL LUNG CANCER

Cyclin B_1、P34~(cdc2)在非小细胞肺癌中的表达及意义

Studies on the expression of Cyclin D1 and apoptosis in the ER(-) breast cancer cell line MDA-MB-435s

Cyclin D1 表达与雌激素受体阴性乳癌细胞株MDA-MB-435s凋亡的研究

The abnormal expression of Cyclin D1 and p16 gene proteins may be one of major pathogeneses of gastric mucosa injury and cell canceration in DGR.

Cyclin D1、p16蛋白表达异常是DGR胃黏膜损伤及癌变的分子机制之一。

Molecular and immunohistochemical analysis of the bcl-1/ cyclin D1 gene in laryngeal squamous cell carcinomas:correlation of protein expression with lymph node metastasis and advanced clinical stage.

cyclin D1与Ras原癌基因的关系很重要，因为Ras失活导致cyclin D1蛋白减少，低磷酸化pRB积聚，G1期停滞。

First ,P27 can suppress the activated CDK that has combined with Cyclin ;

Cyclin D1和p27蛋白阳性表达均为细胞核染色。

The Cyclin D3 protein is a member of the D-type cyclins.

Cyclin D3蛋白是D型细胞周期蛋白中的一员。

The gene expressions of cyclin E,CDK_2 and p21~(WAF1) and their signific ant in esophageal carsinogenesis

Cyclin E、CDK_2和p21~(WAF1)在食管上皮癌变过程中的表达及意义

Cyclin E could be an independent prognostic fac- tor to evaluate the chemotherapeutic sensitivity of breast cancer.

Cyclin E可能作为一种独立的预后因素评估乳腺癌的化疗敏感性。

Cyclin E overexpression was associated with the histological type of EC, being more frequent in non-endometrioid endometrial carcinomas (NEECs, 5 out of 5 case) than in ECs (18 out of 38, 47.37%) (P=0.035).

cyclin E蛋白与子宫内膜癌的组织学类型、分级以及肌层浸润深度显著相关:其在子宫内膜样癌和非内膜样癌中阳性率分别为47.37%和5/5,两者之间比较差异具有统计学意义(P<0.05);

Ccylin D1 and Rb are correlated with some clinicopathologic parameter of BDC, and Cyclin D1 is a valuable prognostic marker of BDC.

CyclinD1,Rb都与胆管癌的一些临床病理参数有关 ,CyclinD1还是提示胆管癌预后的良好标志物。

The positive rates of cyclin D1 and P21 in human lung carcinoma were 66.4%(29/48) and 27.8%(19/48), respectively, and the expression was not related to cell type or clinical TNM stage.

CyclinD1和P2 1 WAF1/CIP1蛋白表达与肿瘤的病理类型和临床TNM分期无关 ;

Compared with those in control group, the protein and mRNA levels of p27Kip1 in MTm (medical dose) group were significantly up-regulated, while the expression of cyclin Dl in MTm group was significantly decreased.

MT诱导细胞凋亡的过程中,与对照组相比,MT药理剂量组H22细胞中的p27Kip1mRNA及蛋白表达升高(P<0.01); cyclinD1mRNA及蛋白表达下降(P<0.01)。

The protein expression of p53 and cyclin D1 increased significantly but the protein expression of p21 decreased significantly(P<0.01).

p21WAF/CIP1基因蛋白表达在低剂量染毒30 d组呈阳性表达,高剂量染毒60 d组表达明显下调(P<0.01)。

P21WAF1 is a kind of cyclin dependent kinase inhibitor, it can be bind to several kinds of cyclin/CDK compounds and arrest the cell cycle.

P21~(WAF1)是一种CKI，它可与多种cyclin/CDK复合物结合，引起细胞周期阻滞。

P27Kipl is a multifunctional cyclin depedent kinase inhibitor (CKI) that was found recently, and to be regarded as a negative regulative restraining gene of cyclin depedent kinase( CDK) for cell cycle.

P27Kipl是近年发现的一个多功能细胞周期蛋白依赖激酶抑制剂(CKI),作为CDK的抑制因子对细胞周期实行负调控。

In PTA 2 weeks group ,cdk4, cyclin D 1 and PCNA expressed mainly in the neointima but with low or undetected expression in the media,the expression of cdk4,cyclin D 1 and PCNA increased with the intimal thickening.

PTA术后 2周组 ,内膜增生显著 ,cdk4、cyclin D1 和PCNA均在内膜层表达 ,而中膜表达较少或几乎检测不到。

Knockdown Cyclin T1 Expression by RNA Interference and Its Effect on Target Cells and HIV-1

RNA干扰下调cyclin T1蛋白的表达及其对靶细胞和HIV-1的影响

The expression of cyclin D1 and CDK4 were detected by RT PCR method.

RT PCR检测细胞周期素D1(cyclinD1)、细胞周期蛋白依赖激酶 4 (CDK4 )mR NA的表达。

Reverse transcription polymerase chain reaction (RT-PCR) was used to detect the expressions of cyclin D1 and cyclin-dependent kinase 4 (CDK4) mRNA in hepatocellular carcinoma tissues.

RT-PCR法检测肝癌组织中细胞周期素D1(cyclinD1)、细胞周期蛋白依赖激酶4(CDK4)mRNA的表达。

Expression and significance of cyclin D_1,CDK_4, p16 and PCNA in T_(24) cell tine

T_(24)细胞系中Cyclin D_1、CDK_4、p16和PCNA的表达状态及其意义

Effects on the protein expression of cyclin A,B_1 and D_1 were assessed by Western Blot.

Western印迹检测细胞周期蛋白D1、A和B1表达的变化。

Wang W,Xu GM,Li ZS,et al.Association between refluxate in esophagus and expression of p53,cyclin D1,p21 and p16 in esophageal mucosa[J].Zhonghua Xiaohua Zazhi(Chin J Dig),2001,21(10):587-589.

[1]王雯,许国铭,李兆申,等.食管内反流物成分与p53、cyclin D1、p21、p16表达的相关性研究[J].中华消化杂志,2001,21(10):587-589.

Shen Q, Yang CM, Zhang GC, et al.Effects of excess thymidine on expression of cyclin[J].J Fouth Mil Med Univ, 2003, 24(6): 510-2.

[5]沈青,杨存明,张国成,等.过量胸苷对细胞周期素表达的影响[J].第四军医大学学报,2003,24(6):510-2.

Keywords Cyclin E;breast neolpasms;taxane;sensitivity;

乳腺肿瘤;紫杉烷;敏感性;

Expression and Activity Identification of Human Cyclin D1 and CDK4 Gene in Insect Expression System

人细胞周期蛋白D1/CDK4基因的真核表达及生物活性鉴定

Expression and Identification of Human Cyclin D1 and CDK4 Proteins

人细胞周期蛋白D1及细胞周期蛋白激酶CDK4的原核表达及鉴定

Expression of Cyclin D_1 in Human Stomach Adenocarcinoma Cell BGC-823 Cell Line

人胃腺癌BGC-823细胞株周期素D_1的表达

Alteration of the Cyclin D1/p16-pRB Pathway, Cellular Proliferation and Apoptosis in Gliomas

人脑胶质瘤中cyclin D1/p16-pRB路径异常以及细胞增殖和凋亡的变化

Cyclin dependent protein kinase

依赖细胞周期蛋白激酶

Cyclin dependent protein kinase 4

依赖细胞周期蛋白激酶4

Immunofluorescence analysis. Primary antibodies were monoclonal antibodies of p21, cyclin D1, CDK4. FITC-labeled secondary antibodies were used. The fluorescence was measured by Coulter EPICS XL.

免疫荧光分析：第一抗体为细胞周期蛋白D1(cyelin D1)、细胞周期蛋白依赖性激酶4(CDK4)、p21蛋白的单克隆抗体，第二抗体采用荧光素标记，应用流式细胞仪检测荧光强度。

Keywords ATRA;B（a）P;cyclin D1;E2F;cell cycle;

全反式视黄酸;苯并（a）芘;细胞周期素D1;转录因子;细胞周期;

Keywords cyclin A;leukemia;leukemia cell;hexamethylene bisacetamide;cell cycle;

关键词细胞周期蛋白A;白血病;白血病细胞;六亚甲基二乙酰胺;细胞周期;

Keywords calcitonin gene-related peptide;vascular smooth muscle cell;proliferation;diamide;cyclin;

关键词降钙素基因相关肽;血管平滑肌细胞;增殖;联胺;周期蛋白;

Keywords BMPs;receptor;epithelia;oral;squamous cell carcinoma;cyclin;apoptosis;

关键词骨形成蛋白;受体;口腔上皮;鳞癌;周期蛋白;凋亡;

Formation, activition and degradation of cyclin - dependent kinase(CDK) and cyclin complex are the main molecular foundation.

其中细胞周期素依赖性激酶(cyclin-dependent kinase，CDK)与细胞周期素(cyclin)复合体的形成、激活与失活是细胞周期调控的主要分子基础。

IN SITU HYBIDIZATION STUDY ON EXPRESSION OF SEVERAL cyclin AND CDK GENES IN HUMAN BREAST CARCINOMA

利用原位杂交分析几种cyclin和CDK基因在人乳腺癌中的异常表达

Keywords Cyclin E;p57kip2;Epithelial tumor of the ovary;Immunohistochemistry;

卵巢上皮性肿瘤;免疫组织化学方法;

The factors that regulate the cell cycle include Cyclin, Cyclin-dependent kinase(CDK), Cyclin-dependent kinase inhibitor(CKI). CyclinDl is the major control switches in the G1 phase.

参与细胞周期调控的蛋白主要有：细胞周期蛋白(Cyclin)、细胞周期蛋白依赖性激酶(Cyclin-dependent kinase，CDK)、细胞周期蛋白依赖性激酶抑制因子(Cyclin-dependent kinase inhibitor，CKI)。

Quantitative study on expression of cyclin D1 and CDK4 in oral lichen planus(OLP)

口腔扁平苔癣中细胞周期素和细胞周期蛋白依赖性激酶4表达的定量分析

Keywords chlorophyllin;trans-BPDE;cyclin;anti-malignant transformation;

叶绿酸;反式-7;8-二羟-9;10-环氧苯并芘;细胞周期素;抗恶变;

Conclusion Different expression of cyclin E enables to affect growth of MCF 7 cell by the changes of cell cycle related genes.

同时pRB的低磷酸化形式增多 ,并下调p2 7。 结论 cyclinE的表达可以影响乳腺癌MCF 7细胞的生长及增殖 ,并可能通过pRB的磷酸化而影响细胞周期G1 S期移行 ,而实现其调节功能

Homology among cyclins is often limited to a relatively conserved domain of about 100 amino acids, the cyclin box, which is responsible for CDK binding and activation.

同种属的cyclin通常有大约100个氨基酸的相对保守序列，这个序列在与CDK结合和CDK活化中起作用。

Keywords EGCG;Mesangial cell;Diabetic nephropathy;Cyclin kinase inhibitor p27;

周期素激酶抑制剂;系膜细胞;糖尿病肾病;

Cyclin prognosis of lung cancer patients.

周期蛋白

The expression of CDK_4, Cyclin D_1, P~(16) proteins in 105 patients with laryngeal squamous cell carcinomas

喉鳞癌组织中CDK_4、cyclin D_1、P~(16)蛋白表达

But no significant difference was found between UL and BLM,P>0.05.Conclusion: The abnormal expression of cyclin G1 and p16 protein was associated with the pathogenesis and development of LMS.

在UL组与BLM组,cyc lin G1和p16蛋白阳性表达率和表达强度均无明显差异(P>0.05)。

We demonstrated that in vitro different plant NAP1 proteins interact with cyclin B and tubulin, suggesting that NAP1 proteins may be involved in tubulin dynamics.

在体外，不同植物NAP1蛋白以不同强度结合不同类型的组蛋白，另外，NAP1蛋白还结合cyclin B以及tubulin蛋白，显示它们可能参与到tubulin的动态调节中。

The high expression of cyclin E and the low expression of p27 in uterine leiomyoma were closely related to dysmenorrhea, the infiltration depth of endometriosis, and the size of adenomyoma, but had no relation to menorrhagia.

在子宫腺肌病中,cyclinE高表达及P27低表达与痛经、异位内膜浸润肌层深度及腺肌瘤的大小有关,而与月经过多无明显关系。

Keywords Digan Oral Liquid;radiation lesion;cyclin D1 gene;adherent molecule;

地甘口服液;辐射损伤;细胞周期素基因;粘附分子;

Positive group includes cyclin, cyclin-dependent kinase (CDK), and downstream targets such as retinoblastoma protein (pRb) and so on.

增多的细胞不是血液中炎性细胞的浸润，而是受损组织固有细胞的增生。

Keywords proliferating cell nuclear antigen;cyclin D1;stomach neoplasms;

增殖核抗原;细胞周期蛋白D1;胃肿瘤;

Proliferating cell nuclear antigen ( PCNA) is also called cyclin, a kind of intranuclear protein, which is a assistant protein of DNase.

增殖细胞核抗原(Proliferating cell nuclear antigen PCNA)又称周期蛋白。

Keywords Cyclin A;Physarum polyphalum;cell cycle;immunoelectron microscope;nuclear protein;

多头绒泡菌;细胞周期;免疫电镜;核蛋白;

Cyclin-cdk compound is composed of Cyclin and cdk different cell cycle.

多种肿瘤存在着Cyclin的异常表达，cdk的激活及其抑制因子的丢失。

Keywords allitridi;stomach neoplasms;cell cycle;cyclin B1;microtubule;

大蒜素;胃肿瘤;细胞周期;细胞周期蛋白B1;微管;

Keywords Emodin;Vascular smooth muscle cell;Cell cycle;Cyclin D1;

大黄素;血管平滑肌细胞;细胞周期;细胞周期素D1;

Keywords mantle cell lymphoma;lymphomas;non-Hodgkin s;Cyclin D1;

套细胞淋巴瘤;淋巴瘤;非霍奇金;细胞周期素D1;

Keywords Endometrial carcinoma;P27;Cyclin E;Prognosis;

子宫内膜癌;p27;细胞周期蛋白E;预后;

Keywords Cervical neoplasm;Carcinoma;squamous cell;Centrosome;Cyclin E;

宫颈肿瘤;中心体;细胞周期蛋白E;癌;鳞状细胞;

In order to build up a gastric carcinoma cell expressing human cyclin G2 gene stably, a useful tool for the research on the function of cyclin G2 in gastric carcinoma cell cycle regulation was made.

应用脂质体基因转染技术建立稳定表达cyclin G2基因的胃癌克隆细胞，为深入研究cyclin G2在胃癌细胞周期调控的作用和机制提供理想的生物学模型。

Keywords allotetraploids;cyclin B gene;intron;molecular genetic relationships;

异源四倍体鲫鲤;细胞周期蛋白B基因;内含子;分子遗传关系;

Keywords isoliquiritigenin;cell cycle;cervix neoplasmas;cyclin B;

异甘草素;细胞周期;宫颈肿瘤;蛋白B;

The cyclin E/cdk_2 kinase activities in HCMV-infected MRC_(-5) cells were relative to the levels of cyclinE essentially.

感染细胞中CyclinE/cdk_2激酶活性基本上与CyclinE含量相关联。

Cyclin D1 and CDK4 proteins were expressed correctly in insect cells and had their biological activity.

成功构建了细胞周期蛋白D1及CDK4真核杆状病毒表达载体 ,并且在昆虫细胞中正确表达了具有生物活性的细胞周期蛋白D1及CDK4融合蛋白 .

Conclusions: Overexpression of cyclin D1 and CDK4 may involve in the onco-pathogenesis of ESC.

我们在相应的癌旁组织中亦发现cyclin D1和 CDK4的过表达。

Our lab previously reported CDK11P58, a G2/M CDK, acts as a partner of cyclin D3 in G2/M phase.

我们实验室报导了一个G2/M期的CDK-CDK11P58,也能特异地与cyclin D3在G2/M期相互作用。

A little effect was shown on Cyclin D 13）When added with20%CBP for12and24hours，Giemsa staining and FCM didn't detect typical apoptosis，but the control group showed4.71%and5.76%of apoptosis rate.

我们实验室曾用混合脐带血浆输注来治疗急性白血病化疗后末梢血白细胞减少、重症再生障碍性贫血等，取得了较好的疗效[5]，因此，脐血是个值得利用的宝贵资源。

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