nucleoside单词基本解析：

n.核苷
n. [生化]核苷
n.核苷；

nucleoside变化用词：

nucleoside英英释义：

Noun

1. a glycoside formed by partial hydrolysis of a nucleic acid

名词 nucleoside:

a glycoside formed by partial hydrolysis of a nucleic acid

nucleoside[ 'nju:kliəsaid ]n.a glycoside formed by partial hydrolysis of a nucleic acid

nucleoside中文词源：

nucleoside用法和例句：

Cytidine ( cytosine nucleoside ) A NUCLEOSIDE formed when cytosine is linked to Dribose via a � � - glycosidic bond.

胞嘧 啶 核苷:当胞嘧啶通过β - 糖苷键与D- 核糖接合形成的核苷.

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To study efficiency of nucleoside peptide nutrient on antioxidation function of rat by 3 dosage group.

目的采用核肽营养素三个不同剂量组来研究对大鼠抗氧化功能的影响.

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Another concept is to prevent drug resistance and optimal management of strategy was nucleoside resistance mutation.

而另一种观念认为最佳的办法是阻止核苷(酸)类似物耐药的发生.

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This paper summarizes the general separation techniques nucleoside compounds and the applications at home and abroad.

综述了国内外核苷类化合物分离技术及应用状况.

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Denovo combination therapy with peginterferon and nucleoside analogues should also be studied I think.

对于聚乙二醇干扰素与核苷类似物的联合初始治疗也是需要进一步研究.

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Most of the novel nucleoside and glycosides compounds revealed certain pharmacology activities in vitro.

首次发现所合成的大部分核苷和糖苷化合物具有较强或很强的体外药理活性.

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nucleoside

generic designation for series of nucleoside 5'-monophosphoric acid

5 '-单磷酸核苷同系物的通用符号

generic designation for series of nucleoside 5'-diphosphoric acids

5'-二磷酸核苷同系物的通用符号

519 nucleoside naive CHB patients were treated with daily dose of ETV 0.5 mg(258 patients)or LVD 100 mg(261patients)for at least 52 weeks.

519例核苷类初治的CHB患者,随机分为ETV组(0.5mg/d)258例和LVD组(100mg/d)261例,用药时间至少52周。

When in HBeAg positive chronic hepatitis B patients with nucleoside analogous antiviral therapy, there are two target as HBV DNA decline or HBeAg seroconversion, which target is more important?

HBeAg阳性的慢乙肝患者使用核苷类药物进行抗病毒治疗，有两个目标需要达到，病毒含量下降或者HBeAg血清阴转，哪一个更加重要？

nucleoside triphosphate phosphohydrolase

NPH

T-cell selective nucleoside analogue

T细胞选择性核苷类似物

(Deoxy)nucleoside phosphate kinase

[脱氧]核苷酸磷酸激酶

Q: Now the treatment of chronic hepatitis B stress on antiviral treatment, but the nucleoside drugs prone to resistance, what are the consequences once happened resistance?

《国际肝病》：现在慢乙肝强调抗病毒治疗，但核苷类药物容易出现耐药，一旦出现耐药有什么后果?

Keywords Panax notoginseng;Nucleoside;Nucleobase;High-performance liquid chromatography（HPLC）;

三七;核苷;碱基;高效液相色谱法;

Nucleoside triphosphate hydrolase

三磷酸核苷水解酶

Nucleoside tdphosphate hydrolase (NTPase)

三磷酸核苷水解酶基因

nucleoside triphosphate phosphohydrolase(NPH)

三磷酸核苷磷酸水解酶

But studies of reverse transcriptase, informed by knowledge of the enzyme's gene sequence, have enabled drug developers to introduce less toxic nucleoside analogues.

不过继续研究反转录酶的基因序列，已经发展出毒性比较弱的核苷类似物，拉美夫锭（lamivudine）正是其中的一种。

Keywords Brevibacterium acetylicum;Nucleoside phosphorylase;5-Fluorouridine;

乙酰短杆菌;核苷磷酸化酶;5-氟尿苷;

Long-term treatment with the second-generation nucleoside analogue lamivudine (lam) efficiently inhibits HBV replication with frequent viral polymerase mutations.

二代拉米夫定的长期应用可以有效地抑制病毒多聚酶突变频繁的HBV发生复制。

Intracellular nucleoside diphosphate can antagonize the ATP induced inhibition of the channel opening and stimulate the channel to open.

二磷酸核苷与其特异性位点结合，不仅降低通道对ATP的敏感性，而且可直接诱导通道开放。

nucleoside diphosphate hexose

二磷酸核苷己糖

nucleoside diphosphate kinase

二磷酸核苷激酶, 核苷二磷酸激酶

NuDP-sugar, nucleoside diphosphate sugar

二磷酸核苷糖, NuDP-糖

Keywords Enterobacter aerogenes;Nucleoside phosphorylase;Induction;Adenine arabinoside;

产气肠杆菌;核苷磷酸化酶;诱导;阿糖腺苷;

Keywords Enterobacter aerogenes;arabinofuranosyluracil;adenine arabinoside;uridine phosphorylase;purine nucleoside phosphorylase;

产气肠杆菌;阿糖尿苷;阿糖腺苷;尿苷磷酸化酶;嘌呤核苷磷酸化酶;

But if the patients have cirrhosis, which means severe disease, then what we generally do is do not stop nucleoside or nucleotide analogue.

但是如果患者有肝硬化，这种严重的疾病时候，我们一般所要做的都是不要停止核苷酸或者核苷类似物等药物。

I am optimistic this will happen but we first need data from clinical trials to establish the usefulness of nucleoside analogues in decompensated cirrhosis.

但是我们需要临床试验的数据支持核苷类似物在失代偿肝硬化中的有效性。

Q: The hepatitis B patients which treat with interferon now appear rebound, you recommend the application to other type of interferon, or switch to nucleoside drugs?

使用干扰素进行治疗乙型肝炎患者现在发现有反弹，你建议对于该情况，是改用别的干扰素还是改用核苷类药物？

Effect of Bao Xin on Cyclic Nucleoside Phosphate Level in Vascular Smooth Muscle of Rats with Myocardial Hypertrophic Heart Failure

保心康对心肌肥大型心力衰竭大鼠血管平滑肌环核苷酸水平的影响

Studies are under way to test the efficacy of treating HBV infection by combining an immune modulator with a nucleoside or nucleotide analogue inhibitor.

免疫调节剂和核苷/核苷类似物联合治疗HBV感染的研究正在进行。

Keywords HIV;Nucleoside reverse transcriptase inhibitors （NRTIs）;Azidothymidine （AZT）;PEG;Modify;Pharmacokinetics;Tissue distributions;

关键词HIV;核苷类逆转录酶抑制剂;齐多夫定;聚乙二醇;修饰;药物动力学;组织分布;

Keywords Hepatitis B virus;Nucleoside analogues;Molecular mechanism of drug-resistance;

关键词乙型肝炎病毒;核苷类药物;耐药分子机制;

Keywords Cordyceps kyushuensis;nucleoside;cordycepin;adenosine;capillary zone electrophoresis;

关键词九州虫草;核苷;虫草素;腺苷;毛细管区带电泳;

Keywords Receptors for purines and pyrimidines? Pathology;Therapeutics? Nucleoside? Nucleotide;

关键词嘌呤与嘧啶受体;病理学;治疗学;核苷;核苷酸;

Keywords Head and neck neoplasms/pathol;Carcinoma;squasmous cell/pathol;Lymphatic metastasis;genes;suppressor;tumor;Nucleoside diphosphate kinases;

关键词头颈部肿瘤/病理学;癌;鳞状细胞/病理学;淋巴转移;基因;抑制;肿瘤;二磷酸核苷激酶类;

Keywords Yishen-Huoxue Fang（YHF） Nephrotic syndrome Puromycin amino nucleoside（PAN） Bone morphogenetic protein（BMP）;

关键词益肾活血方;肾病综合征;嘌呤霉素氨基核苷;骨形态蛋白;

The second category is a nucleoside treatment to fulminant represented.

其二是核苷类治疗，以拉咪呋啶为代表。

Keywords pressurized solvent extraction;high performance liquid chromatography;Cordyceps;ergosterol;nucleoside;base;

加压溶剂提取;高效液相色谱法;虫草;麦角甾醇;核苷;碱基;

Keywords 3-O-Methyl-D-chiro-inositol;Carbocyclic nucleoside analogues;Adenine;Regioselectivity;

右旋肌醇甲醚;碳环核苷类似物;腺嘌呤;区域选择性;

Mechanism of Action: Stavudine, a nucleoside analogue of thymidine, inhibits the replication of HIV in human cells in vitro.

司他夫定是胸苷核苷类似物，可抑制HIV病毒在人体细胞内的复制。

The purine and pyrimidine may be complexed with a sugar to produce a nucleoside.

嘌呤和嘧啶可以同一个糖复合,产生一个核苷。

The purine and pyrimidine may be complexed with a sugar to produce a nucleoside

嘌呤和嘧啶可以同一个糖复合，产生一个核苷。

Keywords Purine nucleoside Regulation Breeding Technology;

嘌呤核苷;调节;菌种选育;工艺;

purine nucleoside phosphorylase

嘌呤核苷磷酸化酶

Study on Killing Effects of Purine Nucleoside Phosphorylase/Fludarabine (PNP/fludarabine) Suicide Gene System on Human Hepatocellular Carcinoma Cell Line BEL7402 in vitro

嘌呤核苷磷酸化酶/氟达拉滨(PNP/fludarabine)自杀基因系统对人肝癌细胞系BEL7402体外杀伤效应的研究

Cloning and expression of purine nucleoside phosphorylase in Escherichia coli

嘌呤核苷磷酸化酶基因的克隆及原核表达载体的构建

purine nucleoside phosphorylase deficiency

嘌呤核苷磷酸化酶缺陷

pyrimidine nucleoside precursor

嘧啶核苷前体

Keywords Pyrimidine nucleoside phosphorylase;Dynamic simulation;Induction;

嘧啶核苷磷酸化酶;动力学模拟;诱导作用;

Keywords pyrimidine nucleoside phosphorylase;cancer research;clinical application;

嘧啶核苷磷酸化酶;癌症研究;临床应用;

Pyrimidine Nucleoside Phosphorylase and the Evaluation of Anticancer Drugs

嘧啶核苷磷酸化酶与抗癌药物治疗效果的评价

So analogs, including nucleoside and nucleotide analogs are now potent drugs, which suppress complicated viral replication of HVC, I will say in 70% to 90% of the patients.

因此，现在核苷类药物是强效药物，能抑制复杂的丙肝病毒复制，我认为能抑制70%到90%的患者。

A lot of literatures were cited to summarize some new nucleoside reverse transcriptase inhibitors in clinical application.Some new active substances in pre-clinical studies were introduced.

在查阅文献的基础上,综述、介绍了近年来上市的、包括复方制剂在内的几种核苷类抗艾滋病新药以及正在研究中的新化合物。

E. coli purine nucleoside phosphorylase

大肠杆菌嘌呤核苷磷酸化酶

Effects of E. Coli purine nucleoside phosphorylase suicide gene therapy on gastric cancer cells

大肠杆菌嘌呤核苷磷酸化酶自杀基因对人胃癌细胞的作用

Several of the agents that inhibit genome replication are nucleoside or nucleotide analogues, which resemble the building blocks of genes.

好几种抑制基因复制的药物是核苷或核苷酸的类似物，它们与基因的组成单位十分相似。

If we select to use nucleoside analogues, then you should select drugs proven to be safe for pregnancy.And for other nucleoside drugs, we don't have enough data for safety in pregnancy.

如果我们选择核苷类似物治疗，应该选择那些被证明对于妊娠是安全的药物，对于其他的一些核苷类药物，我们还是没有证据证实它们在妊娠期间的安全性。

It is linked to nucleoside analogues (a class of drugs that prevent healthy cells from becoming infected with HIV), although the condition may occur more commonly with Stavudine.

它常与核苷类药物（一种可阻止健康细胞转化为感染艾滋病毒细胞的药物）联系在一起，尽管如此，这种疾病的产生与司他夫定联系在一起的几率更大。

Cloning and Prokaryotic Expression of Bombyx mori Nucleoside Diphosphate Kinase Ecoding Gene

家蚕核苷二磷酸激酶基因的克隆和原核表达

Given the ongoing developments in the nucleoside analogous class of therapeuties, how do you view the path forward in this field?

对于目前核苷类似物以及核苷酸药物治疗的现状，你个人如何看待该领域的进展？

De novo combination therapy with peginterferon and nucleoside analogues should also be studied I think.

对于聚乙二醇干扰素与核苷类似物的联合初始治疗也是需要进一步研究。

Combinations of a protease inhibitor with two nucleoside reverse transcriptase inhibitors are currently recommended for postexposure prophylaxis of relatively high-risk exposures.

对相对高危暴露，目前推荐用一个蛋白酶抑制剂结合两个逆转录酶抑制剂作暴露后预防治疗。

A white, odorless powder, C9H12N2O6, that is the nucleoside of uracil, important in carbohydrate metabolism, and used in biochemical experiments.

尿苷白色无味粉末，C9H12N2O6，是尿嘧啶中的核苷，在糖类新陈代谢作用中很重要，用于生化实验中

6.A white, odorless powder, C9H12N2O6, that is the nucleoside of uracil, important in carbohydrate metabolism, and used in biochemical experiments.

尿苷，白色无味粉末，c9h12n2o6，是尿嘧啶中的核苷，在糖类新陈代谢作用中很重要，用于生化实验中。

acyclic nucleoside phosphonates

开环膦酸核苷类药物

Isonucleosides represent a new class of nucleoside analogues.

异核苷代表了一类新的核苷类似物。

When resistance occurs with an oral agent, I think you have to use combination therapy, most often with a nucleoside and nucleotide analogue.

当用口服药物耐药发生的时候，我想你最好使用联合治疗。最常是核苷和核苷酸类似物联合应用。

The enthalpy of hydrogen bond formation between the nucleoside bases 2-deoxyguanosine (dG) and 2-deoxycytidine (dC) has been determined by direct measurement.

很明显，前面的句子是关于一个最近发现的酵母基因，而第二句则着重强调了它有一个和动物一致的基因。另外一个例子：[1

Keywords Plasmodium falciparum;Purine nucleoside phosphorylase;clone;expression;

恶性疟原虫;嘌呤核酸磷酸化酶;克隆;表达;

Delavirdine is indicated in combination with protease inhibitors and nucleoside reverse transcriptase inhibitor for the treatment of HIV-infection.

抗HIV新药地拉韦定是一种非核苷类的逆转录酶抑制剂，是由法玛西亚普强公司研制开发的。

Keywords nucleoside anticancer agent;nucleoside analogue;IMPDH inhibitor;nucleoside phosphoramidate;

抗癌化疗剂;核苷类似物;IMPDH抑制剂;核苷氨基磷酸酯前药;

Lamivudine is a typical antivius agent of pyrimidine nucleoside,mainly used for the treatment of hepatitis B.

拉米夫定是一种嘧啶核苷类抗病毒药物,主要用于慢性乙型肝炎的治疗。

Lamiudine (LAM) is a nucleoside analogue widely used for the treatment of chronic hepatitis B irus (HB) infection.

拉米夫定是一种核苷类似物，被广泛应用于治疗慢性乙肝。

Lamivudine, and most nucleoside analogues, acts by suppression of viral replication through competitive inhibition of reverse transcriptase and DNA polymerase.

拉米还有大多数的核苷类似物，通过竞争性地阻断翻转录酶和DNA聚合酶来抑制病毒复制。

Lamivudine is a typical antivius agent of pyrimidine nucleoside, mainly used for the treatment of hepatitis B.

摘要拉米夫定是一种嘧啶核苷类抗病毒药物，主要用于慢性乙型肝炎的治疗。

Lamivudine, a nucleoside analogue, has been used in China since 1998, which has brought new hope to the Hepatitis B patients.

摘要核苷类似物拉米夫定于1998年在我国上市，为乙型肝炎的抗病毒治疗带来了新的希望。

Nucleoside analogues have attracted more and more attention as their outstanding antiviral and anticancer bioactivity.

摘要核苷类化合物由于其显著的抗病毒、抗癌等生理活性而受到广泛关注。

Carbocyclic nucleosides are nucleoside derivatives with special structures and interesting bioactivities, especially antiviral activities.

摘要碳环核苷是一类结构特殊且具有多种生物活性，其中特别是抗病毒活性的核苷衍生物。

Abstract: As a kind of purine nucleoside,many physiological and pathological actions of adenosine are personalized by the combination with its corresponding adenosine receptor.

摘要： 作为一种嘌呤核苷，腺苷的多种生理及病理作用均是通过与其相应的受体结合来体现的。

Abstract: Nucleoside diphosphate kinase（NDPK） encoding genes are highly conservative in the evolution, but NDPKs reveal various biological funcions.

文章摘要: 核苷二磷酸激酶（NDPK）基因在进化中高度保守,却又呈现复杂多样的生物学功能。

Method:The effect of HDM was observed in puromycin amino nucleoside induced nephrotic syndrome model of rat.

方法:采用嘌呤霉素致肾病综合征大鼠模型,观察黄芪当归合剂对肾小球系膜细胞和肾间质成纤维细胞表型变化的影响。

Acquiring and Sequence Analysis of the Nucleoside Diphosphate Kinase Gene of Schistosoma Japonicum

日本血吸虫核苷二磷酸激酶基因的获得和序列分析

Some nucleoside and nucleotide analogues may cause renal toxicity, myopathy, and/or mitochondrial toxicity.

有些核甘和核甘类似物可能会引起肾脏毒性、肌肉病变和/或粒腺体毒性。

Nucleoside mimetics with modified glycon and/or aglycon and their biological activity was described. And antiviralnucleosides was focused in particular.

本文简述了核苷的种类及其生物活性。根据分子结构的不同,对现有核苷作了分类、归纳,展望了核苷类药物的研究方向。

用作名词(n.)

Isonucleosides represent a new class of nucleoside analogues.
异核苷代表了一类新的核苷类似物。

The second category is a nucleoside treatment to fulminant represented.
其二是核苷类治疗，以拉咪呋啶为代表。

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