lovastatin是什么意思   lovastatin怎么读

lovastatin单词基本解析：

lovastatin变化用词：

lovastatin英英释义：

1. an oral drug (trade name Mevacor) to reduce blood cholesterol levels; used when dietary changes have proved inadequate

名词 lovastatin:

an oral drug (trade name Mevacor) to reduce blood cholesterol levels; used when dietary changes have proved inadequate

同义词：Mevacor

lovastatin中文词源：

lovastatin用法和例句：

Objective To review the advances on lovastatin fermentation by Aspergillus terrus.

目的综述土曲霉洛伐他汀发酵研究的进展.

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Objective To construct one of yield lovastatin strain that is a very valid medicine for cholesterol - lowering.

目的探索构建洛伐他汀高产菌株的原生质体制备和融合方法.

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Methods: Simvastatin was synthesized from lovastatin via acetylization, methylation, hydrolytic decomposition and cyclization reactions.

方法: 以洛伐他汀为原料,通过酰化 、 甲基化 、 水解、环合等反应合成了辛伐他汀.

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lovastatin

Experimental study: To reproduce high fat diet rat models with hyperlipidemia and atherosclerosis, to observe the effect of Xuezhikang and Lovastatin on TC, TQ LDL-C, HDL-C after 30 days.

2．实验研究，复制食饵性高脂血症大鼠模型，随机分为血脂康胶囊组、洛伐他汀组和空白对照组，检测给药30天后对血脂(TG、TC、LDL-C、HDL-C)的影响；

And rats of L-NNA+lovastatin-treated group were intraperitonealy injected with L-NNA at dose of 20 mg/kg daily for 3 d in the first three day of lovastatin injection.

L-NNA+洛伐他汀处理组大鼠在注射洛伐他汀前3天加L-NNA(20mg/kg)腹腔注射，每天1次，连续3天。

Effects of lovastatin on the expression of HMG-CoA reductase mRNA and proliferation capacity of HL-60 cells

Lovastatin对HL-60细胞HMG-CoA还原酶mRNA表达及细胞增殖功能的影响

The up-regulated expression of Caspase-3 protein and Fas antigen, down-regulated expression of Bcl-2 in HL-60 cells maybe play key role in lovastatin inhibiting proliferation and inducing apoptosis of HL-60 cells.

LOV能上调HL-60细胞Caspase-3蛋白和Fas抗原表达，下调Bcl-2表达，推测这可能是LOV抑制HL-60细胞增殖并诱导其凋亡的重要分子机制。

Different concentrations of lovastatin had obvious inhibitive effects on the proliferation of RMC compared with control group(P<0.01).

不同浓度洛伐他汀对大鼠系膜细胞增殖均有明显的抑制作用,与对照组比较有明显差异(P<0.01)。

Study of Effect of Mean - dose Lovastatin in the Treatment of Essential Hyperlipidemia

中剂量洛伐他汀与弹性酶治疗原发性高脂血症研究

Keywords Danqi Capsule;Lovastatin;Lipid;

丹七胶囊;洛伐他汀;血脂;

Main products (APIs) for export: Spiramycin, Spiramycin adipate, Spiramycin embonate, Acetylspiramycin, Erythromycin thiocyanate, Lovastatin, Kitasamycin, Imiquimod, Finasteride, Alprazolam, and all kinds of finished dosage forms.

主要出口产品：螺旋霉素、己二酸螺旋霉素、恩波酸螺旋霉素、乙酰螺旋霉素、硫氰酸红霉素、洛伐他汀、吉他霉素、咪喹莫特、非那雄胺、阿普唑仑和各种制剂产品。

Han D C, Lee S K, Hwang S D, et al. Lovastatin prevents glomerulosclerosis in streptozotozin-induced diabetic uninephrectomized rats[J]. Kidney Int, 1993, 44: 1181.

于力方,陈香美,黎磊石.正常人肾小球系膜细胞培养的研究[J].中华肾脏病杂志,1990,6(2):70.

Keywords Lovastatin;Breast cancer;Cholesterol;Cell cycle;Gap junctional intercellular communication （GJIC）;

关键词洛伐他汀;乳腺肿瘤;胆固醇;细胞周期;GJIC;

Keywords Coronary artery disease;Inflammation;Rosiglitazone;Lovastatin;

冠状动脉疾病;炎症;罗格列酮;洛伐他汀;

Keywords Coronary syndrome;Lovastatin;Fluvastatin;C reactive protein;

冠状动脉综合征;洛伐他汀;氟伐他汀;C-反应蛋白;

A high performance liquid chromatography-diode array detection-electrospray ionization tandem mass spectrometry method was developed for analysis and identification of impurities in lovastatin.

利用高效液相色谱-二极管阵列检测器-质谱联用方法对洛伐他丁及其杂质成分进行分离分析和结构鉴定。

lovastatin fermentation

发酵液

Keywords Response surface design;Lovastatin;Aspergillus terreus;Fermentation;

响应面设计法;洛伐他汀;土曲霉;发酵;

HZ-818 wass selected as the adsorbent for isolating lovastatin from the filtered fermentation broth.

国产HZ-818作为分离纯化洛伐他汀的吸附剂；

The optimum fermentation carbon- nitrogen utilization conditions of the strain BTL 2 3 were obtained by the uniform design method,and the result was implemented into the fermentation process for the mass production of lovastatin.

在对菌株 BTL2 3进行碳、氮源考察的基础上 ,采用均匀设计方法对培养基进行优化 ,使 BTL2 3成功用于洛伐他汀生产实际。

Compound Lovastatin - Nicotinic Acid Sustained - Release Tablet

复方洛汀烟酸缓释片

Beigel Y.Fuchs J.Snir M Lovastatin therapy in hypercholesterolemia:effect on fibrinogen,hemorheologic parameters,platelet activity,and red blood cell morphology 1991(6

宋洪涛.郭涛.宓鹤鸣.张跃新.储文功.张倩中药红曲对高脂血症鹌鹑模型的降血脂作用[期刊论文]-卫生研究1998(5

Good separations of polynuclear aromatic compounds, alkylbenzenes, basic aromatic compounds, halobenzenes as well as lovastatin and simvastatin were achieved.

实验证明这种交联聚合包覆固定相对有机流动相和碱具有高稳定性。

After flight, the strain was rejuvenized, segregated and selected.The content of Lovastatin produced in the solid fermentation was examined.

对搭载后的菌株进行复壮、分离和筛选,并进行固体发酵,检测发酵产物中洛伐他汀产量。

Keywords SFDA;Bama miniature pig;lovastatin;AUC（S0）;absolute bioavailability;first pass effect;

巴马香猪;洛伐他汀;零阶矩药-时曲线下面积;绝对生物利用度;首过效应;

Preliminary studies on conditions for microbial conversion of lovastatin

微生物转化洛伐他汀条件的初步研究

In the process of manufacturing Lovastatin Tablets, two kinds of refuses, fermentation refuse and refining refuse, are produced.

摘要 洛伐他汀生产过程中产生发酵渣和提炼渣。

Objective To study the efficacy and adverse effects of lovastatin combined with metronidazole in treatment of hyperlipidemia, and to explore its possible mechanisms.

摘要目的观察小剂量甲硝唑合洛伐他汀调治高脂血症的疗效与副作用，并探讨其可能的机理。

Abstract: Objective To isolate and purify lovastatin from fermentation broth of Aspergillus terreus by macroporous adsorptive resins.

摘要：目的 用大孔吸附树脂法分离纯化洛伐他汀，提高洛伐他汀成品收率，适应工业化生产的需要。

Methods 135 patients with hyperlipidemia were randomly allocated to two groups: Lovastatin group and XUEZHIKANG group.

方法将135例老年高脂血症患者随机分为洛伐他汀组和血脂康组；

Method The studies on lovastatin fermentation by Aspergillus terrus was reviewed.

方法根据国内外相关文献,对土曲霉洛伐他汀发酵研究的情况进行整理和归纳。

Methods A total of 180 patients with hyperlipidemia were randomly assigned into the metronidazole combined with lovastatin group or the metronidazole alone group.

方法选取高脂血症病人180例，随机分为两组，治疗组用甲硝唑合洛伐他汀联合治疗；

This study was designed to investigate the effects of lovastatin on proliferation and gap junctional intercellular communication (GJIC) of MCF 7 human breast cancer cells.

本文探讨洛伐他汀对人乳腺癌细胞MCF-7增殖功能以及间隙连接细胞通讯(gapjunctionalintercellularcommunication,GJIC)的影响。

mevacor see lovastatin

洛伐他丁, 美降脂, 洛凡司丁

Keywords Lovastatin;impurity;high performance liquid chromatography;diode array detection;mass spectrometry;identification;

洛伐他丁;杂质;高效液相色谱;二极管阵列检测;质谱;鉴别;

Keywords lovastatin;MCF 7 cell;protein expression;phosphorylation levels;MAPK activity;

洛伐他汀;MCF-7细胞;蛋白表达;磷酸化水平;MAPK活性;

Keywords lovastatin;lovastatin fermentation;extraction;

洛伐他汀;发酵液;提取;

Keywords lovastatin;Aspergillus terreus;mycelial pellet;

洛伐他汀;土曲霉;菌丝球;

Keywords Lovastatin, Aspergillus terreus, mycelial form frequence, pellet,free hyphal ,hair length,fermentation;

洛伐他汀;土曲霉;菌体形态;频率;菌球;游离菌丝;毛发长度;发酵;

Keywords lovastatin;Bama-minipig;long-term toxicity test;

洛伐他汀;巴马香猪;长期毒性试验;

Keywords lovastatin;purification and extraction;crystallization;

洛伐他汀;提取精制;结晶;

Keywords lovastatin;osmotic pump tablet;heterogeneous factor;homogeneous factor;multiple factorial experiment design;

洛伐他汀;渗透泵片;相似因子;相异因子;复合析因设计;

Keywords lovastatin;niacin;sustained-release tablet;HPMC;release rate;

洛伐他汀;烟酸;缓释片;羟丙基甲基纤维素;释放度;

Keywords lovastatin;delayed-action preparations;chromatography;high pressure liquid;pharmacoki-netics;biological availability;bioequivalence;

洛伐他汀;迟效制剂;色谱法;高压液相;药动学;生物利用度;生物等效性;

Keywords lovastatin;hyperlipidemia;glomerular injury;platelet-derived growth factor;fibronection;

洛伐他汀;高脂血症;肾小球损伤;血小板源生长因子;纤维连接蛋白;

Keywords Lovastatin producing strain;mutagenesis;high-yield strain;improved fermentation techmology;

洛伐他汀产生菌;诱变;高产菌株;发酵工艺优化;

Effects of lovastatin on the expression of Fas antigen of HL-60 cells

洛伐他汀对HL-60细胞Fas抗原表达的影响

THE EFFECT OF LOVASTATIN ON PLASMA ENDOTHELIUM-DEPENDENT VASOMOTOR FACTORS IN PATIENTS WITH UNSTABLE ANGINA PECTORIS

洛伐他汀对不稳定型心绞痛患者血浆内皮依赖性血管舒缩因子水平的影响

Effect of lovastatin on proliferation and extracellular matrix secretion in cyst-lining epithelial cells of autosomal dominant polycystic kidney disease

洛伐他汀对多囊肾囊肿衬里上皮细胞增殖和细胞外基质分泌的影响

Effects of lovastatin on the expression of bone morphogenetic protein 2 and alkaline phosphatase activity of osteoblast

洛伐他汀对成骨细胞骨形态发生蛋白2表达及碱性磷酸酶活性的影响

Effects of Lovastatin on C-reactive Protein and Adhesive Molecule Levels in Patients with Progressive Stroke

洛伐他汀对进展性脑卒中患者C-反应蛋白及细胞粘附分子的影响

Effects of lovastatin on insulin sensitivity, vascular endothelial function and microcirculation in primary hypercholesterolemia of with coronary heart disease

洛伐他汀治疗冠心病高胆固醇血症对血管内皮功能微循环及胰岛素敏感性的影响

sustain-realease tablets of niacin and lovastatin

洛伐他汀烟酸缓释片

Lovastatin tablets

洛伐他汀片剂

lovastatin sustained-release tablets

洛伐他汀缓释片

A Study of the Pharmacokinetics and Bioavailability of Sustained-release Lovastatin Capsules in Dogs

洛伐他汀缓释胶囊在犬体内的药动学与生物利用度研究

Keywords Niacin;Lovastatin;HPMC;Hydrogel matrix tablet;Release mechanism;

烟酸;洛伐他汀;HPMC;亲水凝胶骨架片;释放机理;

Ultraviolet spectrometry and HPLC were used to determine the content of Lovastatin capsule.In the meantime,we compared the results by the two means.

用紫外分光光度法测定洛伐他汀胶囊的含量,并将测定结果与高效液相色谱法的测定结果进行比较。

Objective:To clinically observe the effect of lovastatin on patients with unstable angina pectoris(UA).

目的:探讨洛伐他汀对不稳定性心绞痛(UA)患者的血脂、心脏缺血事件发生情况的影响。

Objective To review the advances on lovastatin fermentation by Aspergillus terrus.

目的综述土曲霉洛伐他汀发酵研究的进展。

Objective To study the efficacy and adverse effects of lovastatin combined with metronidazole in treatment of hyperlipidemia,and to explore its possible mechanisms.

目的观察小剂量甲硝唑合洛伐他汀调治高脂血症的疗效与副作用,并探讨其可能的机理。

Objective To select high Lovastatin producing microbial breed by space flight.

目的选育高产洛伐他汀的红曲霉菌菌株。

Optimization of Experimental Conditions on Lovastatin Yield Through Monascus

红曲固态发酵生产洛伐他汀的实验条件优化

Keywords monascus;lovastatin;solid-state fermentation;orthogonal design;optimization;

红曲霉;洛伐他汀;固态发酵;正交试验;优化;

Result Mutants with high productivity of Lovastatin were obtained.A series of tests showed that the acquired character of the mutants was stable.Conclusion Space flight is an effective ...

结果从众多分离到的变异菌株中筛选到十几株高产洛伐他汀的菌株,一系列实验表明其高产性状是稳定的。

Conclusion With the advances of basic research about fungi producing lovastatin in the molecule and cell level,the optimization of lov...

结论随着洛伐他汀产生菌的分子、细胞水平基础研究的加强,其发酵工艺的优化将更有意义。

It gives an review of the national and international quantitative identification methods for Lovastatin in Monascus;a summery of characteristics and comparison of each identification method.

综述了国内外各种检测红曲中洛伐他汀含量的方法,总结了各种方法的特点,并将它们进行了比较。

Keywords Zhibituo;Lovastatin;Drug evaluation;

脂必妥;洛伐他汀;药物评价;

Effect of Lovastatin on Brachial Endothelium-dependent Vasodilation in Patients With Hypercholesterolemia

血脂康对高脂血症患者血管内皮舒张功能的影响

By using the UV and Li Cl compound mutagenic agents screening process,the protoplast mutation of lovastatin producing strain was conducted,and two high- yielding strains,BTL 2 3 and BT2 5 respectively were isolated.

采用紫外线 -氯化锂复合诱变洛伐汀产生菌原生质体 ,经原生质体再生获得高产菌株 BTL 2 3、BTL5 6。

The efficacy and safety comparison of acipimox, lovastatin in treatment on aged people with combined hyperlipidemia

阿昔莫司、洛伐他汀治疗老年混合型高脂血症随机对照研究

Furberg CD,Adama AP,Applegate WB,et al.Effect of lovastatin on early carotid atherosclerosis and cardiovascular events (ACAPS)[J].Circulation,1994,90(4):1679.

陆宗良,寇文容,徐义枢,等.乐瓦停治疗原发性和继发性高脂血症的临床观察[J].中国循环杂志,1992,7(1):30.

Test for residual toluene and cyclohexene in crude product of lovastatin by Top-Air-GC

顶空气相色谱法测定洛伐他汀中甲苯及环己烷残留量

Identification of Impurities in Lovastatin by High Performance Liquid Chromatography-Diode Array Detection-Mass Spectrometry

高效液相色谱-质谱联用分析洛伐他丁中的杂质

Keywords HPLC;Lovastatin;Related substance;Quality study;

高效液相色谱法;洛伐他汀;有关物质;质量研究;