atorvastatin是什么意思   atorvastatin怎么读

atorvastatin单词基本解析：

atorvastatin变化用词：

atorvastatin英英释义：

1. an oral drug (trade name Lipitor) that is effective in lowering triglycerides; potent in reducing LDL cholesterol because higher doses can be given

名词 atorvastatin:

an oral drug (trade name Lipitor) that is effective in lowering triglycerides; potent in reducing LDL cholesterol because higher doses can be given

同义词：Lipitor

atorvastatin中文词源：

atorvastatin用法和例句：

Atorvastatin exhibits its effect of cardiovascular protection in different ways.

应用阿托伐他汀能从不同途径发挥独特的心血管保护效应.

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In this text, we reviewed the effect of atorvastatin on the treatment of cardiac myocyte hypertrophy.

本文从心肌细胞肥大这个角度阐述阿托伐他汀对心室重塑的影响.

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Conclusion: Atorvastatin, which is metabolited through the cytochrome P 450 ( CYP ) 3 A 4 Pathway, does not inhibits the antiplatelet activity of clopidogrel.

结论: 经细胞色素P4503A4 ( CYP3A4 ) 途径代谢的阿托伐他汀不抑制氯吡格雷的抗血小板活性.

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Objective To investigate the effect of atorvastatin on expression of E 3 - RSI κ B and UBC 5 in ECV 304 cells.

目的通过研究阿托伐他汀对人血管内皮细胞泛素系统中E3RSIκB酶mRNA及 UBC5酶mRNA表达的影响,探讨其抗炎机制.

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Results After 12 weeks administration of atorvastatin, the levels of CD 63 , CD 62 P were all reduced ( P & lt; 0.05 ).

结果60例患者经阿托伐他汀治疗12周后血小板CD63 、 CD62P测定值显著低于治疗前水平 ( P & lt; 0.05 ).

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Crystalline sodium atorvastatin, compositions containing the same and methods for the production thereof.

结晶阿托伐他汀钠, 含有该物质的组合物以及其制备方法.

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OBJECTIVE To observe the effect of atorvastatin on the treatment of hypercholesterolemia and its mechanism.

目的:观察阿托伐他汀钙片治疗高胆固醇血症疗效,并探讨其机制.

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atorvastatin

A 65-year-old woman with primary hypercholesterolaemia developed hepatitis with characteristics of autoimmune hepatitis while receiving atorvastatin.

1例65岁妇女因原发性高胆固醇血症接受阿伐他汀治疗，而并发以自身免疫性肝炎为特征的肝损害。

After 12 weeks administration of atorvastatin, the levels of CD63,CD62P were all reduced (P<0.05).

60例患者经阿托伐他汀治疗12周后血小板CD63、CD62P测定值显著低于治疗前水平(P<0.05)。

Both A and Bgroup of ACS patients had lower TC, LDL-C ,and CRP levels than beforeatorvastatin treatment,but there were a much stronger TC, LDL-C and CRPdecrease in patients taking 40mg/d atorvastatin (P<0.05) .

ACS 患者应用不同剂量阿托伐他汀后 TC、LDL-C、CRP 都有下降趋势,但应用较大剂量阿托伐他汀时血清 TC、LDL-C、CRP 的下降程度更显著（P<0.05）。

Atorvastatin [50 mg/(kg,d)] and appropriate amounts of distilled water were administered to ATV group for 10 weeks by gavage.

ATV组大鼠给以阿托伐他汀50mg/(kg·d)加适量蒸馏水灌胃。

Effect of HMG-COA Reductase Gene Polymorphism on the Rate of Reaching Lipid Target in Hyperlipidemic CHD Subjects Using Atorvastatin

HMG-COA还原酶基因多态性及阿托伐他汀对冠心病高脂血症患者降脂达标率的研究

Professor Shephard: The atorvastatin and amlodipine combination is a particular case in point.

Shephard教授：阿托伐他汀和氨氯地平的联合应用确实是一个特别的例子。

Experimental Study on the Expression of VCAM-1, ICAM-1 and PAI-1 in Atheroclerosis and Anti-atherosclerosis of Atorvastatin

VCAM-1、ICAM-1和PAI-1在动脉粥样硬化中的表达以及阿托伐他汀抗动脉粥样硬化的实验研究

The powders of Panax notoginseng and panax quinque folium L combined with atorvastatin are efficient and safe in treating CHD patients with abnormal lipids metabolism.

三七西洋参粉与阿托伐他汀联合治疗伴有脂质代谢异常的冠心病疗效确切,安全有效。

Effects of different Dosage of Atorvastatin on Inflammatory Response, Platelet Activity and Fibrinolytic Activity of Patients with Acute Coronary Syndrome

不同剂量阿托伐他汀对急性冠脉综合征患者体内炎症反应、血小板活性及纤溶活性的影响

Clinical trials confirm different level remission of transaminase disorders, steatosis, inflammation and liver fibrosis with treatment of rosiglitazone, metformin, atorvastatin Vitamins E and C etc.

临床试验证实罗格列酮,二甲双胍,维生素E和C,阿托伐他汀等治疗可不同程度地缓解转氨酶异常、脂肪变性、炎症和肝纤维化。

The main finding of SPARCL, he said, was that atorvastatin reduced the risk of stroke by 16 percent in patients who recently had a stroke or TIA, a condition in which blood flow to a portion of the brain is temporarily reduced.

他说，SPARCL研究最大的发现是：阿托伐他汀能降低16%在最近有卒中和短暂性缺血（就是一部分的脑血流暂时性的减少的情况）发作经历的患者的再次卒中的危险。

However, the researchers "found no evidence that systemic atorvastatin administration produced any significant effect on bone mass or markers."

但是研究者们发现：系统使用阿托伐他汀对骨量或骨的标记物没有显著影响。

Clinical study of low molecular weight heparin and atorvastatin on patients with unstable angina pectoris

低分子肝素钙和阿托伐他汀联用治疗不稳定型心绞痛临床研究

Keywords C-reactive protein;LDL-cholesterol;Congestive Heart Failure;atorvastatin （Lipitor）;

关键词C-反应蛋白;低密度脂蛋白胆固醇;充血性心力衰竭;立普妥;

Keywords Coronary heart disease;Heart failure;Percutaneous coronary intervention;Prognosis;Atorvastatin;

关键词冠心病;心衰;介入治疗;预后;阿托伐他汀;

Keywords Coronary heart disease;ACS;Inflammation response;Platelet activity;Fibrinolytic activity;Atorvastatin;Aggressive lipid lowering;

关键词冠心病;急性冠脉综合征;炎症反应;血小板活性;纤溶活性;阿托伐他汀;强化降脂;

Keywords Atorvastatin;Coronary heart disease;Endothelium functions;

关键词阿托伐他汀;冠心病;内皮功能;

Keywords atorvastatin;brain ischemia/cerebral;drug therapy;TTC;CD34;micro-vessel count;

关键词阿托伐他汀;脑缺血;药物疗法;红四氮唑;CD34;微血管计数;

Changes of serum lipid peroxidation level and HO-1 activity in patients with coronary artery disease and treatment effect of atorvastatin

冠心病患者脂质过氧化水平与HO-1活性变化及阿托伐他汀的干预效果研究

The effects and safety of different dosage of atorvastatin in coronary heart disease patients with dyslipoproteinemia ......

冠心病；血脂；安全性；阿托伐他汀

Keywords artery calcification;atorvastatin;alendronate;OPG;RANKL;rat;

动脉钙化;阿托伐他汀;阿伦膦酸钠;OPG;RANKL;大鼠;

Relationship between reactive oxygen species and endothelial dysfunction in hypertension and effects of atorvastatin therapy

原发性高血压患者血管内皮功能失调与活性氧的关系及阿托伐他汀治疗的影响

Keywords atomic force microscope;aortic valve;endothelial cell;high cholesterol diet;atorvastatin;rabbits;

原子力显微镜;主动脉瓣膜;内皮细胞;高脂饮食;阿托伐他汀;兔;

Pravastatin, simvastatin, atorvastatin, fluvastatin, gemfibrozil and fenofibrate had a confirmed effect in secondary prevention.

吉非贝齐一级预防虽降低心血管的死亡率,但不降低总死亡率;

International Circulation: The ASCOT-LLA trial demonstrated the significant benefits of adding atorvastatin to hypertension treatment in adults with three or more risk factors for heart disease.

国际循环：ASCOT-LLA试验证明阿托伐他汀在高血压伴有三个以上心血管危险因素的患者成效显著。

International Circulation: Do you feel the new data coming out for atorvastatin and amlodipine is encouraging that this combination in a polypill will be helpful?

国际循环：您认为应用阿托伐他汀和氨氯地平的多效药片是否对患者有帮助？

In the IDEAL study, 8,888 patients with a history of myocardial infarction (MI) were randomised to receive atorvastatin 80 mg/day or simvastatin given at the standard 20 to 40 mg (S20-40).

在IDEAL研究中，共有8，888名有心肌梗死史的患者被随机分组，一组每天给予阿托伐他汀80毫克，另一组每天给予辛伐他汀20到40毫克(S20-40)。

In SPARCL, 4,732 patients at high risk for stroke because of a previous stroke or transient ischemic attack were randomized in equal numbers to treatment with atorvastatin or placebo.

在SPARCL试验中，4732例有中风病史或短暂性脑缺血发作的脑卒中高危患者，被随机、均等人数分为：阿托伐他汀治疗组、安慰剂组，两组。

Many researches have indicated the intervention with atorvastatin on the development of ventricular remodeling.

大量研究表明阿托伐他汀可干预心室重塑的形成和发展。

However, in an unplanned analysis, atorvastatin seemed to slightly increase the risk of brain hemorrhage.

尽管如此，在一个不是计划中的分析中却发现，阿托伐他汀似乎可以轻微的增加脑出血的危险性。

Atorvastatin exhibits its effect of cardiovascular protection in different ways.

应用阿托伐他汀能从不同途径发挥独特的心血管保护效应。

Keywords acute coronary artery syndromes;percutaneous coronary intervention;vulnerable plaque;Atorvastatin;C-reactive protein;matrix metalloprotease 9;adverse reaction;

急性冠脉综合征;经皮冠脉介入治疗术;易损斑块;阿托伐他汀;C反应蛋白;类金属蛋白酶-9;不良反应;

The short-term effect of different dose of atorvastatin on inflammatory factors in patients with acute coronary syndrome

急性冠脉综合征初期不同剂量阿托伐他汀短期治疗对炎症因子的影响

Keywords Acute myocardial infarction;Nitric oxide;Nitric oxide synthase;Atorvastatin;

急性心肌梗死;一氧化氮;一氧化氮合酶;阿托伐他汀;

Effects of atorvastatin calcium on oxidative low density lipoprotein and soluble intercellular adhesion molecule-1 in patients with acute cerebral infarction

急性脑梗死患者氧化低密度脂蛋白和可溶性细胞黏附因子1对阿伐他汀钙干预的反应

Autonomic nervous function in patients with chronic congestive heart failure and intervention of atorvastatin

慢性充血性心力衰竭患者自主神经功能与阿托伐他汀的干预

I think that kind of combination where you are looking at the major elements of risk is the one that drug companies should tackling， and amlodipine and atorvastatin is clearly a good combination.

我认为，能够将主要危险因素的治疗方案相结合的药物是制药公司应该研发的，而阿托伐他汀和氨氯地平的联合方案无疑是一个好的多效药片方案。

Treatment with atorvastatin increased the risk of brain hemorrhage by 68 percent, the report indicates.

报告指出，阿托伐他汀治疗能增加68%的脑出血的风险。

Objective: To investigate the levels of serum lipid, C reactive protein (CRP) in patients with acute coronary syndrome (ACS) and the effects of atorvastatin on levels of blood lipid and CRP.

摘要目的：探索阿托伐他汀对急性冠脉综合征(ACS)患者高脂血症及C反应蛋白(CRP)的作用。

Objective: To investigate the effects of large dose atorvastatin in short time on vascular endothelial function in patients with unstable angina pectoris (UAP) early.

摘要目的：探讨短期大剂量阿托伐他汀对不稳定型心绞痛(UAP)患者早期血管内皮功能改善的疗效。

Objective: To investigate the anti-inflammatory effect of atorvastatin associated with rampril in acute coronary syndromes (ACS) with C-reactive protein (CRP) reduction.

摘要目的：观察阿托伐他汀及雷米普利对急性冠脉综合征(ACS)时血脂、血清C-反应蛋白(CRP)水平的影响。

Objective: To study the long term follow-op outcome of atorvastatin in treatment of unstable angina.

摘要目的：观察阿托伐他汀对不稳定心绞痛的远期疗效。

Abstract:Objective To investigate the effects of coadministration of atorvastatin with ezetimibe on atherosclerosis in New Zealand white rabbits.

摘要：目的 探讨阿托伐他汀联用依折麦布对新西兰白兔动脉粥样硬化的影响。

Abstract：Objective To observe the influence of different doses of atorvastatin on the prognosis of unstable angina.

摘要：目的 观察不同剂量阿托伐他汀对不稳定型心绞痛预后的影响。

Methods:36 young patients ranged from 18 to 39 years old with hyperlipemia were given Atorvastatin with a dose of 10mg qd which lasted 8 weeks.

方法:36例青年高脂血症患者(年龄18~39岁)口服阿托伐他汀10 mg,1次/d,连续治疗8周。

Methods: Ten eight-week-old SHR were randomized into distilled water group(SHR_(DW) group,n=5) and atorvastatin treated group(SHR_(ATV) group,n=5); the age-matched wistar-kyoto rats(WKY)were used as controls(WKYgroup,n=5).

方法:将10只8周龄的SHR随机分为蒸馏水饲养组(SHRDW组,n=5)和阿托伐他汀治疗组(SHRATV组,n=5),并以5只同周龄的正常血压大鼠(WKY)作为对照(WKY组,n=5)。

12 eight-week - old SHR were randomized into atorvastatin group (ATV, n = 6) and SHR group (n=6). 6 age - matched normotensive Wistar- Kyoto rats (WKY) were served as controls.

方法:选用8周龄SHR 12只,随机分为阿托伐他汀治疗组(ATV组,N=6)和SHR组(N=6),并以同周龄 WKY(N=6)作为对照。

Methods Fifty-three patients were divided into two groups treated with simvastatin and atorvastatin respectively.The efficacy and cost were compared.

方法对53例高脂血症患者使用辛伐他汀或阿托伐他汀治疗,进行疗效-价格比较分析。

Sixty-eight patients with essential hypertension(EH) were randomly assigned to receive the conventional treatment(n=22,ACEI,CCB,etc) or 10 mg/d(n=23),or 20 mg/d(n=23) atorvastatin for 8 weeks.

方法将68例EH患者按随机原则分别入选:常规治疗组(22例):不接受任何调脂药物治疗; 阿托伐他汀治疗组:分别接受10 mg/d(23例)和20 mg/d(23例)阿托伐他汀治疗8周。

Methods Sixty subjects with high lipoproteins were given atorvastatin 20 mg qd for 12 weeks. The serum levels of CD63,CD62P were detected before and at 12 weeks after treatment.

方法测定60例高脂蛋白血症在常规治疗基础上,服用阿托伐他汀20mg,治疗12周前后血小板活性CD63、CD62P水平的变化。

Methods Twelve twelve -week-old SHR were randomized into atorvastatin treated group (ATV group, n=6)and distilled water group (DW group,n=6),and Wistar-Kyoto rats (WKY)as normal controls.

方法选用12周龄自发性高血压大鼠12只,随机分为阿托伐他汀治疗组(简称阿托伐他汀组,n=6)和蒸馏水组(n=6),并以正常血压大鼠作为对照组。

Methods The 8-week-old SHR were randomized into atorvastatin treated group (ATV group,n=6),distilled water group (DW group,n=6),and Wistar-Kyoto (WKY) rats as normal controls.

方法选用8周龄SHR12只,随机分为阿托伐他汀治疗组(ATV组,n=6)、蒸馏水组(DW组,n=6),另选6只WKY大鼠作为正常对照。

Effect of early atorvastatin on inflammatory factors in patients with acute coronary syndrome and normal lipidemia

早期应用阿托伐他汀对正常血脂水平急性冠状动脉综合征患者炎症因子干预的观察

Keywords Pravastatin;Atorvastatin;Angina pectoris;unstable type;C-reactive protein;Hyperlipoidemia;

普伐他汀;阿托伐他汀;心绞痛;不稳定型;C反应蛋白质;高脂血症;

Comparative investigation of altered gene expression of artery in diabetic rats by pravastatin and atorvastatin therapy

普伐他汀和阿托伐他汀对糖尿病大鼠动脉组织基因谱表达的对比研究

Keywords Probucol Atorvastatin Acute coronary syndromes Pregnancy-associated plasma protein High sensitivity C-reactive protein;

普罗布考;阿托伐他汀;急性冠脉综合征;妊娠相关血浆蛋白A;高敏C反应蛋白;

In this text, we reviewed the effect of atorvastatin on the treatment of cardiac myocyte hypertrophy.

本文从心肌细胞肥大这个角度阐述阿托伐他汀对心室重塑的影响。

Interventional effect of atorvastatin on matrix metalloproteinase-9 and tissue factor induced by oxidized LDL in human monocytes

氧化低密度脂蛋白对人单核细胞组织因子和基质金属蛋白酶-9活性的影响以及阿托伐他汀的干预作用

Objective To observe the influence of atorvastatin on plasma inflammation cytokines IL-6 and high-sensitive C-reactive protein(hs-CRP) level in patients of acute coronary syndrome(ACS).

目的 探讨早期应用阿托伐他汀对急性冠脉综合征患者血浆白介素-6、高敏C-反应蛋白(hs-CRP)的影响。

AIM: To test the hypothesis that atorvastatin affects T cell-mediated autoimmunity through modulating the balance of Th1/Th2 and reduces the severity of EAM.

目的:探讨阿托伐他汀对实验性自身免疫性心肌炎(EAM)大鼠Th1/Th2偏离的影响及对EAM的治疗价值。

OBJECTIVE To observe the effect of atorvastatin on the treatment of hypercholesterolemia and its mechanism.

目的:观察阿托伐他汀钙片治疗高胆固醇血症疗效,并探讨其机制。

Objective To investigate the effects of atorvastatin and captopril on the extracelluar matrix(ECM) of rat mesangial cells (RMC) under continual high hydrostatic pressure.

目的观察阿托伐他汀和卡托普利干预对连续周期性波动的高静水压下大鼠肾小球系膜细胞(RMC)细胞外基质(ECM)的影响。

Objective To observe the efficacy of atorvastatin treatment on primary hyperlipidemia, and its mechanism and adverse reactions.

目的观察阿托伐他汀治疗原发性高脂血症疗效,并探讨其机制与安全性。

Keywords Atorvastatin Hyperlipidemia Elderly people;

立普妥;高脂血症;老年人;

The first landmark randomised prospective trial published in this field, SALTIRE,17 demonstrated that high-dose atorvastatin does not slow the progression of this disease.

第一个划时代的随机预期试验在这个领域发表，SALTIRE证明高剂量阿托伐他汀不能减慢这种疾病的进程。

The secretion of collagen I of SHR CFs in the 10-7mol/L-10-4mol/L atorvastatin groups were 0.80 0.01, 0.74 0.01, 0.68 0.01 and 0.62 0.02, respectively, all significantly lower than that of control group (0.97 0.02,all P<0.01).

第四军医大学博士学位论文wistar大鼠组分别为9.550，0、19.750，0、25.930，0、30.86%，其中在10一mol几~10碑mo比阿伐他汀作用下两组大鼠间比较具有统计学意义(均P<0.05)。

Atorvastatin,which is metabolited through the cytochrome P450(CYP)3A4 Pathway,does not inhibits the antiplatelet activity of clopidogrel.

经细胞色素P4503A4(CYP3A4)途径代谢的阿托伐他汀不抑制氯吡格雷的抗血小板活性。

Results: After atorvastatin therapy for 2 years,both thickest and thinnest IMT of carotid artery in CAD patients had no significant change(P>0.05).

结果:阿托伐他汀组治疗2年后,冠心病患者颈动脉IMT最厚处和最薄处与治疗前相比均无显著性改变(P>0.05);

Results The significant effects and differences of blood lipid and blood rheology were observed before and after the treatment with atorvastatin(P<0.05).

结果冠心病患者服用阿托伐他汀血脂下降、血液流变学指标有明显改善,治疗前后比较有显著性差异(P<0.05)。

Results: The primary end point occurred in 5% of patients in the atorvastatin arm and in 17% of those in the placebo arm (p = 0.01);

结果：主要终点发生率在阿托伐他汀组为5%，安慰剂组为17%(p=0.01)；

Conclusion Atorvastatin could cause regression of structural changes in IMT of the common carotid artery and improve coagulation system by the nonlipid-lowering with the lipid-lowering.

结论 阿托伐他汀在有效调脂同时可发挥其非调脂作用，逆转或延迟颈动脉IMT的进程，并改善凝血系统。

Conclusion The powders of Panax notoginseng and panax quinque folium L combined with atorvastatin are efficient and safe in treating CHD patients with abnormal lipids metabolism.

结论三七西洋参粉与阿托伐他汀联合治疗伴有脂质代谢异常的冠心病疗效确切,安全有效。

Conclusions: The ARMYDA-ACS trial indicates that even short-term pretreatment with atorvastatin may improve outcomes in patients with ACS undergoing early invasive strategy.

结论：ARMYDA-ACS试验提示，对于行介入治疗的急性冠脉综合征患者来说，即使是阿托伐他汀短期预处理也能改善预后。

Conclusion: Short-term atorvastatin therapy can effectively lower CRP, TG and LDL-C levels in ACS patients.

结论：短期阿托伐他汀治疗可有效降低ACS患者血清中CRP、TG、LDL-C水平。

Conclusions: Atorvastatin may stabilize the atherosclerotic plaque via decreasing the levels of chemokines in patients with CAD.

结论：阿托伐他汀可能通过降低冠心病患者血浆中趋化因子水平起到稳定粥样斑块的作用。

Efficacy and Safety of Treatment for Mixed Hyperlipidemia With Atorvastatin and Extended-Release Nicotinic Acid

联合应用阿托伐他汀和烟酸缓释片治疗混合性高脂血症的疗效及安全性观察

Title: Treatment of traumatic brain injury with a combination therapy of marrow stromal cells and atorvastatin in rats.

联合骨髓间质细胞和阿伐他汀治疗颅脑外伤。

Keywords Phamarcogenomics;HMG-COA reductase;genetic polymorphism;atorvastatin;coronary heart disease;hyperlipidemia;

药物基因组学;HMG-COA还原酶;基因多态性;阿托伐他汀;冠心病;高脂血症;

Keywords pharmacology;atorvastatin;reverse transcription-polymerase chain reaction;ubiquitin-protein ligase enzyme;ubiquitin-conjugating enzyme;arteriosclerosi;

药理学;阿托伐他汀;逆转录聚合酶链反应;泛素蛋白连接酶;泛素缀合酶;动脉粥样硬化;

The trial's main results, previously reported, showed that patients in the atorvastatin group were significantly less likely to experience both stroke and major cardiovascular events.

该试验的主要结果，如先前报告显示：在阿托伐他汀治疗组，患者中风和主要心血管事件发生率均显著降低。