aneuploidy是什么意思   aneuploidy怎么读

英式:['ænjəˌplɒɪdɪ]    美式:['ænjəˌplɒɪdɪ]

aneuploidy单词基本解析:

非整倍性
n. 非整倍性, 异倍性, 异倍体性

aneuploidy变化用词:



aneuploidy英英释义:

Noun

1. an abnormality involving a chromosome number that is not an exact multiple of the haploid number (one chromosome set is incomplete)

名词 aneuploidy:

an abnormality involving a chromosome number that is not an exact multiple of the haploid number (one chromosome set is incomplete)

aneuploidy中文词源:

aneuploidy用法和例句:

Aneuploidy in human population is a serious genetic problem.

在人类群体中非整倍性是个严重的遗传问题.

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Conclusion DNA aneuploidy, SPF and EGFR is associated with malignant degree of gliomas.

结论:DNA异倍体的发生 、 SPF值、EGFR阳性 率与胶质瘤恶性级别正相关.

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One measure of malignancy is aneuploidy by flow cytometry.

恶性肿瘤的检测方法之一是通过流式细胞计显示异倍性.

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DNA aneuploidy is one of the characteristics of malignant tumors.

DNA非整倍体是恶性肿瘤的特征性标志之一.

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Amniocentesis is the standard prenatal detection procedure for aneuploidy.

羊膜穿刺术是出生前检测非整倍体的金标准.

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Objective To establish the method of detecting oocyte aneuploidy by spectral karyotyping ( SKY ) .

目的建立光谱核型 分析检测 人未受精卵细胞非整倍体的方法.

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Results: Aneuploidy had statistic difference in lung carcinoma with lobulation, spiculate and mediastinal lymph node metastasis.

结果: CT显示 分叶征、毛刺征 、 棘突征,有纵隔、肺门淋巴结转移的有无,其DNA异 倍体检出率均有统计学差异.

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The aneuploidy and SPF index are also the important factors which can influent the prognosis.

异倍体的出现以及SPF值是影响预后的重要因素.

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BSR : What first got you interested in looking at the possibility that aneuploidy might cause cancer?

什么原因促使你注意到非整倍体可能是癌症的原因?

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The worse the neoplasm, the greater the degree of aneuploidy and the worse the prognosis.

肿瘤越恶性, 异倍性程度越大,报告结果就越差.

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Objective To study the relationship between DNA aneuploidy and biological behavior of thyroid tumor cells.

目的探讨甲状腺肿瘤细胞DNA倍体类型与肿瘤生物学特性的关系及预后意义.

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One measure of malignancy is aneuploidy flow cytometry flow cytometry pattern of a breast carcinoma.

流式细胞计数仪测量细胞非整倍性是测量恶性肿瘤的方法之一.

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aneuploidy


DNA aneuploidy, DI, SPF and PI are associated with malignant degree of gliomas.

DNA异倍体是恶性胶质瘤特征性标志 ; DI值 ,SPF值、PI值与胶质瘤的级别呈正相关


DNA aneuploidy,SPF and EGFR is associated with malignant degree of gliomas.

DNA异倍体的发生、SPF值、EGFR阳性率与胶质瘤恶性级别正相关。


Keywords Immortal DNA strands;Aneuploidy;Gene mutation;Tumor stem cells;Adult stem cells;label-retaining cells;Cell clonality;Telomere;

DNA永生化链;非整倍体;基因突变;肿瘤干细胞;成体干细胞;标记滞留细胞;细胞克隆形成能力;端粒;


DNA aneuploidy is one of the characteristics of malignant tumors.

DNA非整倍体是恶性肿瘤的特征性标志之一。


Keywords TK gene mutation assay;aneuploidy;TK6;TKE-E6;normal growing colony;slow growing colony;LOH;STR;karyotype;

TK基因突变试验;非整倍体;TK6;TK6-E6;正常生长集落;缓慢生长集落;杂合性丢失;短串联重复序列;核型分析;


Once an abnormal growth is defined as a cancer, or neoplasm, high cellular aneuploidy is also considered by some to be a sign of aggressiveness.

一旦某个异常增生给归类为癌症或肿瘤,也有人将其中细胞的高度非整倍体性,视为癌细胞侵犯性的徵兆。


All along, however, some evidence that was largely ignored continued to support an important role for aneuploidy in the genesis and progression of cancer.

不过一直以来,一些严重遭受忽视的证据,却不断支持非整倍体在癌症发生及发展上扮演的重要角色。


Keywords Centrosome;Genetic instability;Aneuploidy;Chromosome instability;Neoplasms;

中心体;基因不稳定性;非整倍体;染色体不稳定性;肿瘤;


Development in molecular biological methodology of prenatal diagnosis of chromosome aneuploidy

产前诊断胎儿非整倍体的分子生物学方法进展


The preliminary study on correlation between oocyte cytoplasm morphology and aneuploidy

人未受精卵胞浆形态与染色体非整倍体关系的实验研究


Keywords Human Teratospermia;Automosome;Aneuploidy;

人类;畸精症;常染色体;非整倍体;


BSR: What first got you interested in looking at the possibility that aneuploidy might cause cancer?

什么原因促使你注意到非整倍体可能是癌症的原因?


somatic aneuploidy

体细胞非整倍性


Study on the mechanism of oocyte aneuploidy by spectral karyotyping

光谱核型分析检测人未受精卵细胞非整倍体


The application of automated image cytometry in sputum cytologic diagnosis of lung cancer 1. DNA aneuploidy for diagnosis of lung cancer

全自动图象细胞仪在肺癌痰细胞学诊断中的应用1.DNA异倍体作为标志物诊断肺癌


Keywords Oocytes;First polar body;Chromosomes;human;Aneuploidy;Preimplantation genetic diagnosis;In situ hybridization;fluorescence;

卵细胞;第一极体;染色体;人;非整倍性;植入前诊断;原位杂交;荧光;


Keywords PRINS(Primed in situ labeling) Aneuploidy Umbilical blood;

原位引物标记异倍体脐血;


Keywords pronuclear morphology;cleaved-embryo;preimplantation;genetic diagnosis;chromosome;aneuploidy;

原核形态;卵裂胚;诊断;种植前;染色体;非整倍体;


With greater aneuploidy, the protein imbalances increased, and so did the cells' cancerous progression.

同时细胞非整倍体的情形越多,蛋白质不平衡的现象就越明显,细胞的癌化程度也越严重。


Thus, the common denominator of all carcinogens seems to be their initiation of random aneuploidy.

因此,所有致癌物质的共通点,似乎是它们都能随机引起非整倍体。


Aneuploidy in human population is a serious genetic problem.

在人类群体中非整倍性是个严重的遗传问题。


Keywords multicolor PRINS;human sperm;chromosome;aneuploidy;diploid;

多色引物原位标记;精子;染色体;非整倍性;二倍体;


Keywords multicolor fluorescence in situ hybridization(MFISH);chromosomal aberrations;aneuploidy;genetic toxicology;

多色荧光原位杂交;染色体畸变;非整倍体;遗传毒理学;


Detection of aneuploidy in human oocyte by multicolor fluorescence in - situ hybridization

多色荧光原位杂交检测人卵细胞染色体非整倍体方法的建立


Keywords low dose ionizing radiation;human lymphocyte;aneuploidy;chromosome non_disjunction;

小剂量电离辐射;人淋巴细胞;非整倍体;染色体不分离;


Despite its high incidence and severe clinical consequences,very little is known about how aneuploidy originates in human.

尽管非整倍体的发生率高、临床后果严重,但人类对于非整倍体究竟是如何发生的仍然不清楚。


DNA content of paraffin embeded specimens of 45 bladder cancer patients were subjected to both image cytomeric analysis (ICM) and flow cytometry (PCM). DNA aneuploidy was found in 31 with ICM and 20 with FCM.

应用图像分析(ICM)与流式细胞仪(FCM)检测膀胱癌石蜡包埋标本的DNA含量,在45例标本中,ICM检测出异倍体癌31例,而FCM检测出20例。


The aneuploidy and SPF index are also the important factors which can influent the prognosis.

异倍体的出现以及SPF值是影响预后的重要因素。


Keywords PRINS;chromosome;human spermatozoa;aneuploidy;disomy rate;BLAST;

引物原位标记;染色体;人类精子;非整倍性;二体率;序列比对;


Keywords PRINS (Primed in situ labeling) Umbilical blood Prenatal diagnosis Aneuploidy;

引物原位标记;脐血;产前诊断;非整倍体;


One measure of malignancy is aneuploidy by flow cytometry.

恶性肿瘤的检测方法之一是通过流式细胞计显示异倍性。


Preimplantation genetic diagnosis (PGD), used in clinical practice, is offered to couples that may suffer from a monogenetic disorder, chromosome aneuploidy or X-linked disease.

据悉,第三代辅助生殖技术在1990年获得成功。


Abstract Aneuploidy in human population is a serious genetic problem.The major cause of this numerical chromosomal aberration is non - disjunction.

摘要 在人类群体中非整倍性是个严重的遗传问题。


Analysis of chromosomal aneuploidy in bronchoscopically gained cells

支气管镜刷取细胞染色体异倍性的研究


Abstract: Objective To study the relationship between DNA aneuploidy andbiological behavior of thyroid tumor cells.

文摘:目的探讨甲状腺肿瘤细胞DNA倍体类型与肿瘤生物学特性的关系及预后意义。


Methods The DNA aneuploidy style was studied in 73 patients with thyroid lesions using image cytometery and the specimen was acquired by fine-needle aspiration.

方法对73例甲状腺肿瘤和结节性甲状腺肿患者以细针穿刺涂片,用图像细胞仪进行分析。


Being born aneuploid, or prone to aneuploidy, clearly accelerates processes that lead to cancer.

显然,先天带有非整倍体或者后天容易出现非整倍体,都加速了癌症发生的过程。


And Duesberg suggests that foods, drugs and chemicals should be tested to identify compounds that cause aneuploidy.

杜斯伯格并建议对食物、药品及化学物展开测试,以找出会造成非整倍体的物质。


The more the cells deviated from the correct number of chromosomes, the faster aberrations accumulated in their chromosomes.Genomic instability rose exponentially with the degree of aneuploidy.

染色体数目离开正常值越远的细胞,其染色体上偏差的累积速率也越快,基因组的不稳定随著非整倍体的程度成级数增加。


THE ANIMAL MODEL FOR INSPECTION OF ANEUPLOIDY IN PREIMPLANTATION EMBRYOS OF MICE

检测着床前胚胎非整倍性诱变的小鼠动物模型


Early cancers could also be distinguished from morphologically identical benign tumors by checking for aneuploidy.

检测非整倍体的存在与否,也可区分早期的癌细胞与外型相同的良性肿瘤。


Compare aneuploidy.

比较aneuploidy.


One measure of malignancy is aneuploidy by flow cytometry.Pictured here is the flow cytometry pattern of a breast carcinoma.

流式细胞计数仪测量细胞非整倍性是测量恶性肿瘤的方法之一。


Specifically, the men had fewer abnormal sperm in which a chromosome had been lost or gained, known as aneuploidy, they reported in the journal Human Reproduction.

特别地,这些人含有更少的诸如染色体缺失或增加的这类非整倍体的不正常精子,他们在人类生殖杂志报道称。


For her part, the 54-year-old Hunt, now at Washington State University, focuses on aneuploidy, or an abnormal number of chromosomes in eggs that causes birth defects and miscarriages.

现年54岁、任教于华盛顿州立大学的杭特,目前致力于研究会导致先天缺陷和流产的受精卵中非整倍体(染色体数目异常)。


FISH Study of Human Oocytes Failed to Fertilize in vitro Characterised with Chromosome 21 Aneuploidy

用FISH技术研究人类体外未受精卵的21号染色体非整倍体


Unlike other sex chromosome aneuploidy, there are no characteristic physical features for triple X patients.

由于大部分患者缺乏明显的表现型特征,造成本综合征有相当大的鉴别难度。


Objective: To explore the reliability of the method PRINS for detection of spermic aneuploidy.

目的:探索应用引物原位标记技术分析精子染色体非整倍性的可靠性。


Objective:To study the feasibility of PRINS for rapid prenatal diagnosis of fetal aneuploidy metaphase cell from umbilical blood.

目的:探讨PRINS应用于脐血中期染色体快速产前诊断的可行性。


OBJECTIVE:To study the feasibility of interphase fluorescence in situ hybridization (FISH) in detection of chromosomal aneuploidy of X and Y in touch preparations of lung cancer.

目的:探讨间期核荧光原位杂交(FISH)检测肺癌印片标本X和Y染色体异倍性的可行性。


Objective:To investigate the correlation between maternal age and oocyte chromosome aneuploidy abnormality.

目的:直接从卵细胞水平研究女性年龄与其卵细胞染色体非整倍体间的相关关系。


Objective To analyse the clinical significance of the immunophenotype, aneuploidy and cell circle distribution in children with acute leukemia (AL).

目的分析小儿急性白血病(AL)的免疫表型、异倍体、细胞周期分布状况的临床意义。


Objective To establish the method of detecting oocyte aneuploidy by spectral karyotyping (SKY).

目的建立光谱核型分析检测人未受精卵细胞非整倍体的方法。


Objective To study the relationship between DNA aneuploidy andbiological behavior of thyroid tumor cells.

目的探讨甲状腺肿瘤细胞DNA倍体类型与肿瘤生物学特性的关系及预后意义。


Keywords short tandem repeat;aneuploidy;prenatal diagnosis;parental origin;chromosome abnormality;

短串联重复序列;非整倍体;产前诊断;双亲来源;染色体异常;


The researchers hope that, in the future, they can deelop what they are calling “aneuploidy therapy.

研究人员希望将来他们能够研究出他们称之为“非整倍体疗法”的药物。


Researches have shown that flow cytometric DNA analysis can detect DNA aneuploidy in as much as 92% of tumors.

研究显示,流式细胞术DNA倍体分析可以在92%的实体肿瘤上检测到DNA异倍体的存在。


The results was identical as our research before: THH is a aneugen in mammal.We concluded that one of a pathwayof aneuploidy induction by THH was tubulin polymerization inhibiting.

研究结果与我们以往关于THH为非整倍体诱发剂的实验证据相吻合并进一步提示THH可以抑制微管蛋白聚合作为诱发非整倍体的途径之一。


COL may induce the aneuploidy of preimplantation embryos with dose response.

秋水仙素可诱导着床前胚胎细胞出现非整倍性,并呈剂量依赖关系。


The study on correlation between first polar body morphology and oocyte aneuploidy

第一极体形态学与人类卵细胞非整倍体相关关系的研究


The DNA ploidy measurement results showed that the tumor cells were high aneuploidy and the distribution of DNA contents were highly heterogeneous.

经细胞影像仪测定瘤细胞DNA呈高异倍体,DNA质量的分布呈高度异质性。


Results 64% of oocytes were normal, 36% of oocytes were aneuploidy, of which 22% were due to nondisjunction and 14% unbalanced predivision.

结果64%的卵细胞核型正常,36%的卵细胞为非整倍体,其中22%为同源染色体不分离,14%为姐妹染色单体非平衡性过早分离。


Results:Aneuploidy had statistic difference in lung carcinoma with lobulation,spiculate margin,spiculate protuberance and mediastional lymph node matastasis.

结果:CT显示分叶征、毛刺征、棘突征,有纵隔、肺门淋巴结转移的有无,其DNA异倍体检出率均有统计学差异。


Results:The aneuploidy rate in oocytes with granular cytoplasm was 40%,which was much higher than that of oocytes with normal cytoplasm(P<0.05).

结果在形态正常的70个卵母细胞中,非整倍体15个(21.4%);在出现胞浆颗粒化的40个卵母细胞中,非整倍体16个(40%),明显高于形态正常卵母细胞中的非整倍体比例(P<0.05)。


Results The difference of DNA aneuploidy style between benign and malignant tumor cells was significant.

结果甲状腺恶性肿瘤细胞与良性肿瘤细胞DNA倍体类型有非常显著的差异。


Results: The difference of aneuploidy between the endometrial proliferation group and the normal control was of no statistical significance (P>0.05).

结果:子宫内膜增殖症组的异倍体率与正常对照组间的差异无统计学意义(P>0.05);


Amniocentesis is the standard prenatal detection procedure for aneuploidy.

羊膜穿刺术是出生前检测非整倍体的金标准。


Keywords tumor cells;centromeric dots;aneuploidy aberration;

肿瘤细胞;着丝粒点;非整倍性畸变;


The worse the neoplasm, the greater the degree of aneuploidy and the worse the prognosis.

肿瘤越恶性,异倍性程度越大,报告结果就越差。


Keywords embryogenesis;DNA damage;imprinting;aneuploidy;telomere;centrosome;nuclear packaging;male infertility;

胚胎发生;DNA损伤;印迹;非整倍性;端粒;中心体;核包装;男性不育;


Keywords Benzene;Oocytes;Zygote;Aneuploidy;

苯;卵母细胞;合子;非整倍性;


Keywords fluorescence in situ hybridization;Tripterygium hypoglaucum (Level) Hutch;mouse bone {marrow cell};aneuploidy;

荧光原位杂交;昆明山海棠;小鼠骨髓细胞;非整倍体;


Fluorescence in situ hybridization study on the chromosome 17 aneuploidy of human oocytes failing to fertilize in vitro

荧光原位杂交技术研究人类体外未受精卵的17号染色体非整倍体


” Drugs that inhibit accurate deliery of the right number of chromosomes to each new cell, resulting in aneuploidy, would be used to destroy tumors caused by mutations in the tumor suppressors.

该药物能够准确的将正确的染色体数目导入每一新细胞,产生非整倍体细胞,能够用于治疗由于肿瘤抑制基因突变导致的肿瘤。


This example strongly supports the idea that by raising or reducing a cell's normal dosage of thousands of genes at once, aneuploidy produces malignant phenotypes.

这个例子强力支持了下面这个想法:非整倍体在同一时间内,增加或减少细胞内上千个基因的正常量,于是造成了恶性肿瘤的表现。


Keywords atropine;d tubocurarine;tubulin polymerization;aneuploidy;

阿托品;筒箭毒碱;微管蛋白聚合;非整倍体;


Keywords aneuploidy;chromosomal screening;peptide nucleic acid-fluorescence in situ hybridization;primed in situ;spermatozoa;

非整倍体;染色体筛选;缩氨酸核酸荧光原位杂交;引物原位杂交;精子;


Primary Study of the Relationship Between Aneuploidy and Proliferation Phenotypes of Tumor Cells

非整倍体与肿瘤细胞增殖表型关系的初步研究


Progress in the research of aneuploidy genesis

非整倍体发生的研究进展


Aneuploidy is an important point at issue in human reproductive biology,accounting for both a major proportion of miscarriages and various congenital malformation syndromes among newborns.

非整倍体是人类生殖生物学中的重要问题,是引起自发性流产和新生儿中多种先天性畸形综合征的主要原因。