tumorigenesis是什么意思   tumorigenesis怎么读

tumorigenesis单词基本解析：

tumorigenesis变化用词：

tumorigenesis英英释义：

tumorigenesis中文词源：

tumorigenesis用法和例句：

tumorigenesis

Promoter methylation of RASSF1A gene may be involved in the early-stage during thyroid tumorigenesis, and the similar change in P16INK4a gene is related to lymphatic metastasis of PTC.

5．甲状腺乳头状癌组织中RASSF1A基因启动子甲基化可能出现在甲状腺肿瘤发生的早期阶段，P16INK4a基因启动子甲基化在甲状腺乳头状癌的淋巴转移中发挥一定作用。

Expression of Cyclooxygenase-2, STAT Signalling Pathway in Tumorigenesis of of Esophageal Carcinoma and the Effect of Nimesulide on Human Esophageal Carcinoma Cells

COX-2、STAT信号转导通路在食管上皮癌变中的表达及尼美舒利抗食管癌作用机制研究

The abrrent DNA methylation is related to human tumors.The status alteration of DNA methylation is a key factor of tumorigenesis and one of the methods in anti-oncogen inactivation.

DNA甲基化与肿瘤有密切的联系,DNA甲基化状态改变是致癌的一个关键因素,是抑癌基因失活的方式之一。

Aberrant DNA methylation reinforce the gastrical tumorigenesis by promoting gene mutation and enhancing the chromatosome instability ,etc.

DNA的异常甲基化通过影响基因转录,促基因突变,增加染色体结构的不稳定性等多方面促进胃癌的发生发展。

Keywords DNA methylation;hypermethylation;hypomethylation;gene stability;tumorigenesis;

DNA的甲基化;高甲基化;低甲基化;基因稳定性;肿瘤发生;

DNA methylation and its aberrance play an important role in the human development and tumorigenesis.

DNA的甲基化及甲基化异常在人体发育和肿瘤的发生中起着至关重要的作用。

The impact of DOC-2 expression on the tumorigenesis of human ovarian cancer cell line(HO-8910)

DOC-2对卵巢癌细胞HO-8910致瘤力的影响

ID proteins in cell differentiation, cell cycle control and tumorigenesis

ID蛋白与细胞分化、细胞周期调控及肿瘤的发生

Protein and mRNA Expression of MDM2, p53 and Rb in Bladder TCC, Their Correlations, and Their Roles in Tumorigenesis and Prognosis

MDM2，p53，Rb基因mRNA，蛋白表达在膀胱癌发病及预后判断中的作用及其相互关系

P27 is a new kind of tumor suppressor gene ,it acts to contral the cell cycle , to induce apoptosis and to regulate differentiation.The reduced expression of P27 has a relationship with tumorigenesis.

P27是一种新的肿瘤抑制基因，它参与细胞周期的调控、细胞的凋亡及细胞的分化，与肿瘤的发生有关。

The overexpression of p53 and bcl 2 proteins may be involved in tumorigenesis and be correlated with the differentiation of NPSC. These will help identify the prognosis of NPSC.

p5 3和bcl 2蛋白均参与鼻咽鳞癌的发生与分化 ,其表达水平的不同有助于预后判断 ;

The activation of PKC is closely correlated with the tumorigenesis,development and metastasis.

PKC的活化与肿瘤的发生、发展、转移等密切相关。

The loss of PTEN expression is closely related to tumorigenesis and development of the UEC, and the overexpression of p53 gene is related to tumorigenesis and development of the USC.

PTEN突变和表达缺失与宫内膜样癌的发生、发展有关。 p53基因突变和过表达与宫内膜浆液性癌发生发展关系密切。

Rb correlates with tumorigenesis closely, and is an important tumor suppressor gene.

Rb与人类多种肿瘤发生关系密切，是一种重要的肿瘤抑制基因.

Significance of Genetic Alterations of the RB Gene in Colorectal Tumorigenesis

RB基因异常改变在大肠癌发生、发展中的意义

"I found that certain signaling is upregulated, but [nicotine] itself cannot push the cell to undergo tumorigenesis [cancer formation].

“我发现，某些特定的传导信号上调，但[尼古丁]本身不能推动细胞进行肿瘤发生[癌症形成]。

Updates of centrosome anomaly and tumorigenesis

中心体异常与肿瘤发生关系的研究进展

More and more importance is attached to the correlation between centrosome abnormity and tumorigenesis,It refers to multiple genes abnormity,mainly separated into oncogene and tumor suppressor gene.

中心体异常与肿瘤发生的相关性已越来越受到人们的重视。

Centrosome associated regulated proteins and theirs abnormilites and tumorigenesis development

中心体相关调节蛋白及其异常与肿瘤发生的研究进展

To identify differentially expressed genes is an important step to better understand the molecular mechanisms in the tumorigenesis and tumor progression of HCC.

为了更进一步瞭解肝细胞癌肿瘤发生与肿瘤进行过程的分子机制，分析并且辨别差异性表现的基因是非常重要的步骤。

Influence of instability of mitochondrial genome length on tumorigenesis in human tumors

人类肿瘤组织线粒体基因长度不稳定在肿瘤发生学上的角色

These facts suggest that MDM2, p53 and Rb gene harmonize in the tumorigenesis and progression of bladder TCC.

他们在膀胱TCC的发病过程中都发挥了一定的作用，而且相互配合相互影响；

Keywords BAFF;APRIL;humoral immunity;autoimmune disease;tumorigenesis;

体液免疫;自身免疫性疾病;肿瘤发生;

Keywords neuroblastoma;retinoic acid receptor;embryonal adrenal;cell differentiation;tumorigenesis;

关键词神经母细胞瘤;视黄酸受体;胚胎肾上腺;细胞分化;肿瘤发生;

Establish a platform by transcriptome to predict the potential function of CEBPD, ZBRK1 and interested targets in tumorigenesis.

利用系统生物学方法分析抑癌或致癌基因的调控与其功能扮演。

tumorigenesis and development

发生发展

Meta Analysis of the Relationship between Tumorigenesis of Oral Squamous Cell Carcinoma and Human Papillomavirus Infection

口腔鳞癌发生与人类乳头状瘤病毒感染关系的Meta分析

Bmi1,a polycomb group repressor,is tightly related to stem cell self-proliferation and may play a key role in tumorigenesis.

另外,在小鼠精原干细胞中也检测到该基因的表达,表明该基因对精原干细胞的自增殖也有一定的影响。

Additional clinical relevance of bulge cell biology includes the importance of bulge cells as a gene therapy target and their possible roles in tumorigenesis.

另外，有关隆突部细胞的生物学特性的应用在临床上包括作为基因治疗的靶细胞和在肿瘤发生中的作用。

Since normal tissues usually show resistance to TRAIL, TRAIL-sensitiity in neoplasm would be basically acquired during tumorigenesis.

因为正常组织通常表现对TRAIL的抵抗，而在肿瘤发生过程中，新生物通常获得对TRAIL的敏感性。

Accordingly, it is believed that netrin-1 and its receptors may play an important role in tumorigenesis.

因此,netrin1及其受体可能在肿瘤发生过程中发挥重要作用。

Therefore,lucubrating CABYR could provide a new direction for elucidating the tumorigenesis mechanism and its diagnosis and therapy.

因此，对CABYR的深入研究可为阐明人类肿瘤的发生机制及肿瘤的诊断、治疗提供一个新的方向。

DNA hypomethylation plays an important role in tumorigenesis and tumor progression mainly through influences chromosome stability.

在肿瘤的发生、发展过程中,DNA低甲基化比高甲基化更为常见。

Research Progress of Mechanisms of Cell Transformation and Tumorigenesis Induced by Polyomavirus

多瘤病毒诱导细胞转化和致瘤机制的研究进展

Changes of telomerase activity in the tumorigenesis of rat submandibular gland

大鼠颌下腺肿瘤形成过程中端粒酶活性的变化

No significant changeswere observed in morphocytology, tumorigenesis and immune reaction of B16 cells.

对细胞的形态、致瘤性及免疫系统没有显著影响。

Although the UPR has been implicated in tumorigenesis, its precise role in endogenous cancer remains unclear.

尽管UPR参与了肿瘤发生，但其在内源性肿瘤中的确切作用尚不清楚。

Progress of the Relationship Between Stem Cell and Gastrointestinal Tumorigenesis

干细胞与胃肠道肿瘤发生关系的研究进展

They are important for development, tissue cell replenishment, and wound healing in physiological conditions and might be involved in tumorigenesis in pathological conditions.

干细胞对身体发育，体细胞更新，伤口修复，及肿瘤形成均扮演重要的角色。胚胎干细胞源自于早期胚胎。

Keywords Midkine（MK）;Truncation;Tumorigenesis;Cancerization;Early detection;

截短型;肿瘤生成;癌变;早期诊断;

This finding may help to understand the mechanisims of tumorigenesis and instruct clinical therapeutics.It has became a hot spot of research and treatment for the tumor.

所以研究肿瘤干细胞的起源及其与肿瘤的发生关系，成为当前研究和治疗肿瘤领域的新热点。

Dissect the function of CEBPD and CEBPB between inflammation and tumorigenesis.

探讨CEBPD及CEBPB联系炎症与癌症之关系。

These phenomena implicated that the aberrant expression and mutation of m-M-CSF and M-CSFR is closely related to tumorigenesis, and that they might be the potential targets for the immunotherapy of tumors.

提示m-M-CSF和M-CSFR的异常表达和基因突变与恶性肿瘤密切相关，是肿瘤免疫治疗的潜在靶点。

Abstract: Epithelial stem cell plays pivotal role in maintaining epithelial metabolism, hair follicle cycling, repairing the epidermis on injury, and has close relationship with skin tumorigenesis.

摘 要： 表皮干细胞能够维持正常表皮的新陈代谢、毛囊周期循环以及参与创伤情况下创面的修复，皮肤肿瘤的发生也与其密切相关。

Abstract : Increasing evidence suggests that changes in the cellular microenvironment contribute to tumorigenesis, but the molecular basis of these alterations is not well understood.

摘要 ：越来越多的证据显示细胞微环境的改变与癌症的发生是相关的，但是这一变化的分子基础还不甚明了。

Objective To investigate the expression of brain-derived neurotrophic factors (BDNF) in gliomas of human, and explore the relation between BDNF and pathologic grading and tumorigenesis of gliomas.

摘要目的探讨脑源性神经营养因子(BDNF)在人脑胶质瘤内的分布与表达，并探讨它们与肿瘤病理分级的关系及其在肿瘤发生过程中的作用。

Cancer stem cells are defined as rare cells in cancer tissues with indefinite potential for self-renewal that drives tumorigenesis.

摘要肿瘤干细胞是存在于肿瘤组织内数量极少的既保持干细胞自我更新能力又能够导致肿瘤发生、发展的一群细胞。

Background and objective It has been proven that heparanase played an important role in tumorigenesis.

摘要背景与目的已有的研究表明，肝素酶的表达与肿瘤的发生有关。

The proteasome is primarily responsible for intracellular protein degradation.The abnormality of its activity is sign of tumorigenesis.

摘要蛋白酶体负责细胞内蛋白的降解，其活性的异常改变是肿瘤发生的标志。

Role of PTEN in tumorigenesis has been a hotspot of research in tumor domain.

摘要过去，PTEN在肿瘤发生发展中的作用是研究的热点。

This article reviews the advances of researching relation between DNA methylation aberrance and transcription and tumorigenesis in the last decades, especially a recent breakthrough in cancer.

文中主要综述了几十年来人们对DNA甲基化异常与基因转录及肿瘤发生之间关系的研究进展,尤其是最近的研究突破。

Studies of cancer stem cell biology and mechanisms of tumorigenesis are lending insight into the origins of cancer and will ultimately yield new approaches to fight cancer.

明确肿瘤干细胞的生物学性状及其导致肿瘤发生的内在机制，并以肿瘤干细胞为靶标开展相关研究，就有可能为肿瘤治疗提供新的手段并最终为根治恶性肿瘤带来希望。

This review reevaluates the function of the MUC1 on the tumorigenesis and development of the tumor and the application on the tumor diagnosis and immunotherapy.

本文主要阐述MUC1在肿瘤发生发展及其在肿瘤诊断和生物治疗中的作用。

This review summarizes the methylation of related-genes and its relationship with tumorigenesis,early diagnosis,prognosis and therapy.

本文对相关基因甲基化与肿瘤发生,肿瘤的早期诊断、预后判断及治疗的关系进行了阐述。

This article summarizes the research advances and the possible mechanism of PEG10 in tumorigenesis and normal tissue development and differentiation,and revealed the bright prospect.

本文概述PEG10基因在肿瘤发生和正常组织发育分化中的作用,探讨可能的作用机理,展望了其应用前景。

The result suggested that bcl-2/JH fusion might be involved in tumorigenesis of nasopharyngeal epithelium in which mbr-JH and mcr-/JH were the two important aberrant changes in NPC.

本文表明bcl-2/JH融合基因与鼻咽癌发 生可能有一定关系，其中mbr-JH和mcr-JH同为bcl-2基因在鼻咽癌的两个重要基因异常 改变形式。

Inaro H, Onada M, Inafuku N, et al. Potent preventive action of curcumin on radintion-induced initiation of mammary tumorigenesis in rats[J]. Carcinogenesis, 2000,21:1835.

李剑明,扬和平,刘松青.3种姜黄素单体抑制人内皮细胞作用的实验研究[J].重庆医学,2002,31(9):804.

Moreover, it allows researchers to study HCC tumorigenesis, to identify 614 HCC genes, and to identify potential molecular targets for improving HCC diagnosis and therapy.

此资料库可研究肝癌致癌途径、发掘614个肝癌基因、并可发展检测肝癌的基因晶片、发掘分子标的，以利临床诊断及发展治疗癌症的药物。

The Ubiquitin-Proteasome Proteolytic Pathway and Tumorigenesis

泛素介导的蛋白质降解与肿瘤发生

However, the role of EBV in the development of these cancers still remains unclear.Therefore, it is important to investigate the mechanisms underlying EBV-induced tumorigenesis.

然而EB病毒在致癌过程中所扮演的角色仍不清楚，因此研究EB病毒的癌化机制相当重要。

Advance research of the relationship between cyclooxygenase-2 and tumorigenesis

环氧化酶-2与肿瘤发生发展的相关性研究进展

Role of Cyclooxygenase-2 in the Development and Treatment of Bladder CancerObjectives: The mechanism is not very clear during tumorigenesis of bladder cancer.

环氧化酶2在膀胱癌发生发展以及治疗中的作用研究目的：膀胱癌的发病机制尚不十分清楚。

Dysregulation of these core pathways and processes through mutation can explain the major features of pancreatic tumorigenesis.

由于突变而引起的这些核心通路和调节过程的失调，是胰腺癌形成的主要特征性改变。

Nevoid basal cell carcinoma syndrome is a rare autosomal dominant genetic disorder characterized by developmental abnormalities and tumorigenesis.

痣样基底细胞癌综合征是一种罕见的常染色体显性遗传病,以发育异常和肿瘤发生为主要临床特征。

But the mechanism of the tumorigenesis of SV40Tag is not clear.

目前对SV40在肿瘤发生过程中所扮演的具体角色和确切机制还不十分清楚。

Objective To investigate the role of human angiopoietin 1(Ang1) in tumorigenesis and angiogenesis of human gastric cancer cell line SGC7901 in nude mice.

目的 研究人血管生成素 1 (Ang1 )基因转染人胃癌细胞系SGC790 1后 ,对肿瘤细胞生物学特性以及对小鼠体内致瘤力和血管生成的影响 ,探讨其在胃癌发生及血管生成中的作用。

Objective:To investigate the role of anti-oncogene PTEN in the tumorigenesis and development of oral squamous cell carcinoma (OSCC).

目的:探讨抑癌基因PTEN在口腔颌面部鳞状细胞癌发生、发展过程中的作用。

Objective:To detect the expression of O6-methylguanine-DNA methyltransferase (MGMT),and it s effect of promoter hypermethylation on tumorigenesis and progression.

目的:检测大肠癌组织中O6-甲基鸟嘌呤-DNA甲基转移酶(MGMT)的表达情况及其在肿瘤发生发展中的作用和临床意义。

Objectives: To investigate CD154 expression in transitional cell carcinoma(TCC) of bladder and its correlation with tumor stage and tumor grade,and further to explore its effects on tumorigenesis by in vitro and in vivo experiments.

目的:研究CD154在膀胱移行细胞癌(TCC)中的表达及其与肿瘤临床分期和病理分级之间的关系,并通过体外细胞培养以及小鼠膀胱肿瘤模型研究CD154的表达对膀胱TCC成瘤性的影响。

For the last 20 years human leukemic cell lines have represented extremely useful tools for studying the mechanisms of tumorigenesis and the strategy of treatment of human leukemia and other tumors.

目的和意义人白血病细胞系已成为白血病及其它肿瘤研究中最常用的工具之一。

Objective To evaluate the telomeric restriction fragment in the progress of gastric tumorigenesis.

目的探讨不同胃粘膜病变端粒状态的变化规律。

Objective To investigate the role of anti-oncogene PTEN in the tumorigenesis and development of parotid pleomorphic adenoma.

目的探讨抑癌基因PTEN在腮腺多形性腺瘤的发生、发展过程中的作用。

Objective To investigate the tumor angiogenesis in benign, borderline and malignant epithelial ovarian tumors and its relationship with the tumorigenesis.

目的探讨良性、界性和恶性上皮性卵巢肿瘤微血管生成状态及肿瘤微血管生成与卵巢肿瘤发生、展的关系。

Purpose To explore the relationship between retinoic acid receptors and development of human embryonal adrenal and tumorigenesis of neuroblastoma.

目的探讨视黄酸受体基因在人胚肾上腺和神经母细胞瘤中表达的意义。

Objective To analyze differentially expressed genes between hilar and distal cholangiocarcinoma and to clarify the molecular mechanism of tumorigenesis.

目的通过比较肝门部胆管癌与胆总管中下段癌的全基因组表达差异,进一步揭示胆管癌发生、发展的内在分子机制。

We initiated tumorigenesis with a transgene of the protooncogene MET or by hydrodynamic transfection of MET in combination with other genes into the livers of adult animals.

研究人员通过原癌基因MET转基因或水动力转染MET和其他一些基因到成熟小鼠肝脏中，从而触发肿瘤的形成。

It was found that telomerase activity could be detected in most tumor tissue, which suggested that activation of telomerase may play an important role in tumorigenesis.

研究发现,大多数肿瘤组织细胞中可检测到端粒酶活性,其被认为在肿瘤发生中起重要作用。

The identification of the Drosophila ISC niche and the principal self-renewal signal will facilitate further understanding of intestinal homeostasis control and tumorigenesis.

研究干细胞的调控机制，对理解肿瘤等疾病的发生进而有针对性地制定干预措施，以期达到治愈目的具有重要意义。

CONSTRUCTION OF DUAL GENE EUKARYOTIC EXPRESSION RECOMBINANTS FOR STUDY OF RELATIONSHIP BETWEEN POLY(ADP-RIBOSYL)ATION AND TUMORIGENESIS

研究聚ADP核糖基化作用与细胞恶变关系的双基因真核表达重组体的构建

Telomerase appears to be an important factor for the control of cellular proliferation and tumorigenesis.

端粒酵素在调控细胞增殖与癌化扮演重要角色。