neuraminidase是什么意思   neuraminidase怎么读

英式:[njʊə'mɪnədeɪs]    美式:[njʊə'mɪnədeɪs]

neuraminidase单词基本解析:

n.神经氨(糖)酸苷酶,唾液酸苷酶
n. [生化]神经氨(糖)酸苷酶, 唾液酸苷酶

neuraminidase变化用词:



neuraminidase英英释义:

neuraminidase中文词源:

neuraminidase用法和例句:

neuraminidase


Protection and Response Against Influenza A Virus Infection by Hemagglutinin, Neuraminidase DNA Vaccine

A型流感病毒血凝素、神经氨酸酶DNA疫苗研究


“The new neuraminidase gene that came in from Eurasian swine is one we’ve never before seen circulating in humans,” said Rambaut.

“我们以前从未在人体内见过这种出自欧亚猪的新型神经氨酸酶基因。”兰姆伯特说。


“The new neuraminidase gene that came in from Eurasian swine is one we've never before seen circulating in humans,” said Rambaut.

“这种来自欧亚猪的新的神经氨酸酶基因是一种我们从未见过在人类中流行的基因,”拉姆鲍特说。


The two monoclonal antibodies raised against the sialyl - parts of BSM, named 5E2 and 6C10.Their reaction with BSM were blocked by mild KOH, heating, trypsin, periodicacid and neuraminidase treatment.

两株抗体分别命名为5E2和6C10,Western-Blot显示两株抗体均只与分子量大于220kDa的PAS染色阳性条带反应。


AB:We tested the neuraminidase drug sensitivity of clade 1 and clade 2 influenza A (H5N1).

中文简介:我们检测了H5N1病毒的1型和2型对神经氨酸酶药物的敏感性。


Peptide Inhibitors of Influenza Virus Neuraminidase Selected from Phage Random Peptide Library

从噬菌体随机肽库中筛选流感病毒神经氨酸酶的抑制多肽


Sendai virus hemagglutinin neuraminidase was expressed in COS 7 cells.

仙台病毒的血凝素神经氨酸酶 (HN)在COS 7细胞中得到了表达。


We know, for example, that H5N1 is sensitive to antiviral drugs that inhibit one of its important enzymes, called neuraminidase.

例如,我们知道H5N1对抑制神经胺酸酶的抗病毒药物很敏感,神经胺酸酶是此病毒重要的酵素之一。


Keywords Influenza neuraminidase inhibitor;Active site;Acting mechanism;Structure-activity relationship;

关键词流感病毒神经氨酸酶抑制剂;活性位点;作用机制;构效关系;


Keywords paramyxovirus;envelope glycoprotein;expression;cell fusion;neuraminidase;

副粘病毒;包膜糖蛋白;表达;细胞融合;神经氨酸酶;


(2009) Inhibition of Neuraminidase Inhibitor-Resistant Influenza Virus by DAS181, a Novel Sialidase Fusion Protein.

另一姊妹篇:Triana-Baltzer GB, Gubareva LV, Klimov AI, Wurtman DF, Moss RB, et al.


Keywords pyrrolidine;neuraminidase;inhibitor;influenza virus;activity study;

吡咯烷;神经氨酸酶;抑制剂;流感病毒;活性研究;


After the virus infects the cells of the respiratory system and begins replicating, neuraminidase cuts the newly formed copies free to invade other cells.

呼吸系统内的细胞染上病毒,而且病毒开始复制之后,神经氨酸酵素会将新生的病毒切下以便侵犯其他细胞。


Keywords sialic acid and analogs;neuraminidase;inhibitor;

唾液酸与类似物;唾液酸酶;抑制剂;


Neuraminidase prevents the aggregation after releasing from the surface of host cell.

因此,神经氨酸酶成为抗流感病毒药物研究中很有吸引力的靶点。


Most swine influenza viruses have been susceptible to antiviral medications such as neuraminidase inhibitors (oseltamivir and zanamivir).

大多数猪流感病毒对抗病毒药物,例如:抑制剂(奥司他韦和扎那米韦)很敏感。


Rats receied two intraenous injections of either heparinase III to digest HS or neuraminidase to remoe neuraminic acids (positie control).

实验大鼠接受两次肝素酶III注射以消化HS,或两次神经氨酸酶注射以除去神经氨酸(阳性对照)。


The recent progress of the research of neuraminidase inhibitors related to sialic acid in the control of influenza is reviewed.

对结构基于唾液酸类的神经氨酸酶抑制剂在抗流感病毒药物研究中的进展进行了综述。


A SV_(40) late replacement expression vector containing secreted neuraminidase cDNA was transfected into COS cells. High nenraminidase activity could be detected in the cell culture medium.

将含分泌型甲型流感病毒神经氨酸酶cDNA的SV_(40)晚期区段取代载体转染COS细胞后,可在细胞培养液中测出高酶活力。


A cDNA fragment of newcastle disease virus(NDV)strain F48E8 containing partial fusion(F)gene and partial haemagglutinin neuraminidase(HN)gene was obtained by RT PCR.

应用RT-PCR获取新城疫病毒(NDV)F48E8株的部分囊膜糖蛋白基因片段。


Keywords anti-influenza drugs;M2 protein inhibitors;neuraminidase inhibitors;

抗流感病毒药物;M2离子通道蛋白抑制剂;神经氨酸酶抑制剂;


Abstract: Neuraminidase and RBCs have a biochemical interaction.We changed the time of treatment and the dose of neuraminidase to remove the surface charge of RBCs in different degrees.

摘 要: 神经氨酸酶(唾液酸酶)与红细胞发生生物化学作用,分别改变其作用时间和二者的相对作用剂量,以达到不同程度地去掉红细胞的表面电荷。


Methods The sera were directly hydrolyzed with neuraminidase to remove the terminal sialic acid residues on the sugar chains of GGT and eluted with DSA and ConA affinity chromatography column,the sugar chain structure of GGT was analyzed.

方法 以唾液酸酶水解 GGT糖链末端的唾液酸 ,再用 DSA和 Con A亲和层析柱对各种肝病患者血清 GGT进行洗脱 ,结合两种凝集素结合糖链的特性 ,分析其糖链结构。


Methods Separated by neuraminidase,ALP isoenzyme in the serum of 50 normal women and 55 senile women with osteoporosis were analyzed by agarose electrophoresis.

方法采用神经氨酸苷酶,用琼脂糖电泳法对体检正常者50例(对照组)和老年女性骨质疏松患者55例(骨质疏松组)血清中的ALP同工酶进行分离分析。


We report two infants with proven peumococcal meningitis associated with anemia, thrombocytopenia, renal failure, and T-antigen activation characteristic of neuraminidase activity.

本文报告两个婴儿罹患肺炎双球菌脑膜炎并发溶血性贫血、血小板低下、急性肾衰竭、及T-抗原活化。


The acting mechanism and structure-activity relationship of each kind of influenza neuraminidase inhibitors with dissimilar structures were reviewed.

根据化学结构的不同,综述各类神经氨酸酶抑制剂的作用机制及构效关系。


Keywords Influenza virus;DNA vaccine;Bicistronic DNA Vaccine;hemagglutinin;neuraminidase;

流感病毒;DNA疫苗;双表达载体;血凝素;神经氨酸酶;


Keywords Influenza virus;DNA vaccine;Neuraminidase;Co-expression;

流感病毒;DNA疫苗;神经氨酸酶;双表达;


Keywords Influenza;Neuraminidase;Hemagglutinin;DNA vaccine;Inactivated vaccine;Maternal immunity;

流感病毒;神经氨酸酶;血凝素;DNA疫苗;灭活疫苗;母体免疫;


Keywords influenza virus;neuraminidase inhibitor;phage display;

流感病毒;神经氨酸酶抑制剂;噬菌体展示;


Keywords influenza virus;neuraminidase inhibitors;new use;new resources;

流感病毒;神经氨酸酶抑制剂;新作用;新药源;


Keywords influenza virus;hemagglutinin;neuraminidase;phylogenetic tree;

流感病毒;血凝素;神经氨酸酶;种系发生树;


Keywords Influenza virus;Hemagglutinin gene;Neuraminidase gene;Nucleic acid immune;

流感病毒;血凝素基因;神经氨酸酶基因;核酸免疫;


Expression of Neuraminidase of Influenza Virus A in COS Cells

流感病毒神经氨酸酶基因在COS细胞中的表达


Screening of Peptides as Broad-spectrum Neuraminidase Inhibitors against Influenza Viruses

流感病毒神经氨酸酶广谱抑制多肽的筛选研究


ESTABLISHMENT AND APPLICATION OF HIGH THROUGHPUT SCREENING MODEL FOR INFLUENZA VIRUS NEURAMINIDASE INHIBITORS IN VITRO

流感病毒神经氨酸酶抑制剂筛选模型的建立和应用


Morphological and functional alterations of ear in lysosomal neuraminidase gene deficient mouse

溶酶体神经氨酸酶基因缺乏小鼠听觉和耳形态学改变初步研究


The researchers then tested blood samples from 38 human olunteers for their ability to inactiate neuraminidase from an H1N1 irus and two H5N1 iruses.

然后研究人员检测了能够抑制一种H1N1病毒和两种H5N1病毒的神经氨酸苷酶活性的38名志愿者的血液样品。


7.Injection of rats with neuraminidase, however, resulted in a major increase of urinary albumin and was associated with an increase in urinary free neuraminic acid.

然而给大鼠注射神经氨酸酶却可以使尿白蛋白大量增加,并伴有尿液游离神经氨酸增加。


S. treatment of influenza infections in pigs found that Tamiflu and zanamivir for influenza viruses such neuraminidase inhibitor drugs can be effective treatment for swine flu.

然而,美国治疗流感感染猪发现,达菲和扎那米韦等对流感病毒神经氨酸酶抑制剂药物可有效治疗猪流感。


The affinity of selected peptides were assayed by ELISA and the inhibitory activity to influenza virus A/Sydney/5/97 neuraminidase were detected by fluorometric method.

用ELISA方法鉴定噬菌体克隆与靶分子的结合力,用荧光方法测定噬菌体克隆对流感病毒A/Sydney/5/97(H3N2)神经氨酸酶的抑制活性。


After the treatment with neuraminidase, the distributions of WGA receptors changed apparently.

用神经氨酸苷酶处理后,麦胚凝集素受体的分布有明显变化。


The diversity of influenza A arises from variations in the two proteins on its surface, called hemagglutinin (abbreviated H or HA) and neuraminidase (N or NA).

甲型流感病毒的多样性来源于其表面两种蛋白的变化,这两种蛋白就是血凝素(简称A或HA)和神经氨酸酶(简称N或NA)。


Keywords ALP;electrophoresis;isoenzymes;neuraminidase;sialic acid;

碱性磷酸酶;神经氨酸酶;电泳;同工酶;唾液酸;


The efficacy of the neuraminidase inhibitors depends on their administration within 48 hours after symptom onset.

神经氨酶抑制剂的作用效果取决于给药时间,即症状出现后48小时。


neuraminidase ( Neu1 )

神经氨酸酶


Keywords Neuraminidase;Erythrocyte;Shear elastic modulus;Membrane viscosity;

神经氨酸酶;红细胞;剪切弹性模量;表面粘度;


Keywords Neuraminidase;Erythrocyte;Microrheological characteristics;Surface charge;Viscosity;Sedimentation;

神经氨酸酶;红细胞;微观流变特性;表面电荷;粘度;血沉;


Keywords neuraminidase;bone marrow cells;liver;hematopoietic foci formation;

神经氨酸酶;骨髓细胞;肝脏;造血集落形成;


Neuraminidase plays an important role in the pathogenicity of influenza infections.

神经氨酸酶在流感病毒的感染和传播过程中起着重要作用。


neuraminidase gene

神经氨酸酶基因


EFFECTS OF NEURAMINIDASE ON MEMBRANE SHEAR ELASTIC MODULUS AND MEMBRANE VISCOSITY OF RBCs

神经氨酸酶对红细胞膜的剪切弹性模量和表面粘度的影响


neuraminidase inhibition

神经氨酸酶抑制作用, 神经氨糖酸苷酶抑制作用


Influenza neuraminidase inhibitors

神经氨酸酶抑制剂


Neuraminidase is a kind of glycosidoprotein, it resides the surface of influenza virus A and B-, and plays a key part in the process of virus duplication and infection.

神经氨酸酶是存在于A、B型流感病毒表面的糖蛋白,在流感病毒复制和感染过程中起关键酶的作用。


Neuraminidase deficiency with beta-galactosidase deficiency

神经氨酸酶缺乏伴β-半乳糖酶缺乏


Effects of neuraminidase preconditioning on distribution and hematopoietic foci formation of donor bone marrow cells injected intravenously in rats

神经氨酸酶预处理对大鼠骨髓细胞分布及造血集落形成的影响


Neuraminidase (NA) is one of avian influenza virus (AIV) glycoprotein.

神经氨酸酶(Neuraminidase NA )是禽流感病毒(Avian influenza virus AIV)主要糖蛋白之一。


Keywords influenza virus, RT-PCR, diagnosis, recombinant baculovirus, hemagglutinin,,,,, neuraminidase, expression;

禽流感;核蛋白;RT-PCR;诊断;杆状病毒表达;血凝素;神经氨酸酶;疫苗;


Keywords avian influenza;computer-aided drug design;docking;Quantitative structure-activity relationship;M2 ion channel;neuraminidase;hemagglutinin;RNA polymerase;

禽流感;计算机辅助药物设计;分子对接;定量构效关系;M2离子通道;神经氨酸酶;血细胞凝集素;RNA聚合酶;


Keywords Avian Influenza Virus, Haemagglutinin, Neuraminidase,,,,,Nucleoprotein, Recombinant Fowlpox Virus, Protective Immunity, T Lymphocyte;

禽流感病毒;血凝素基因;神经氨酸酶基因;核蛋白基因;重组禽痘病毒;T淋巴细胞;免疫保护力;


The Structure and Biology Function of Avian influenza virus Neuraminidase

禽流感病毒神经氨酸酶的结构及其生物学功能


The results showed that the expressions of PNA and RCA-1 receptors were significantly different between SCC and KA. There was almost no PNA receptor expression in SCC, but after digestion with neuraminidase, PNA became positive in SCC.

结果显示:花生凝集素(PNA)受体和蓖麻凝集素(RCA-1)受体在SCC和KA的表达明显不同,用神经氨酸苷酶消化前SCC中绝大部分无PNA受体表达,而消化后则有PNA受体表达。


Results Liver and bone ALP could be separated by agarose electrophoresis after treatment by neuraminidase.

结果经神经氨酸苷酶处理后,琼脂糖电泳法可以分离肝和骨ALP;两组肝型ALP比较,差异无显著性意义(P>0.05);


hemagglutinin neuraminidase

血细胞凝集素的神经氨酸酶, 血细胞凝集素神经氨酸酶


Construction of Recombinant Adenovirus Expressing Influenza virus Neuraminidase Gene

表达流感病毒神经氨酸酶基因的重组腺病毒的构建


The test uses genetic sequencing to detect the H275Y mutation of the neuraminidase gene, which has been shown to cause resistance to oseltamivir.

该测试使用基因序列探查H275Y神经氨酸苷酶的基因突变,该突变可导致奥司他韦耐药。


This charge is reduced by digestion with neuraminidase.

这一电荷被唾液酸苷酶消化而降低。


Both of these agents are neuraminidase inhibitors with actiity against both influenza A and B iruses.

这两种药嗾使神经氨酶抑制剂,能抵抗流感A、B病毒。


There are two classes of such medicines, 1) adamantanes (amantadine and remantadine), and 2) inhibitors of influenza neuraminidase (oseltamivir and zanamivir).

这种药物有两类:1)金刚烷(金刚烷胺和金刚乙胺);2)流感病毒神经氨酸酶抑制剂(奥司他韦和扎那米韦)。


Key to flu's virulence are a pair of proteins named hemagglutinin and neuraminidase -the H and N in the strain names, respectively.

那您怎么找呢? 一个可能是降落到那个星球上,然后从降落点开始搜寻。


Yi and Zongru Guo , Study on molecular mechanism and 3D-QSAR of influenza neuraminidase inhibitors, Bioorganic &Medicinal Chemistry, 2003, 11(7): 1465

郭彦伸,褚凤鸣,郭宗儒,柏爱萍.环氧合酶-2抑制剂的三维定量构效关系的研究.化学学报2003,61:1114


The virus that was currently detected in the US and Mexico is susceptible to neuraminidase inhibitors but resistant to amantadanes.

问题7:为什么美国和墨西哥的局势代表了一个新的问题?


Vibrio cholera neuraminidase

霍乱弧菌神经氨酸酶


TI :Can immunity induced by the human influenza virus N1 neuraminidase provide some protection from avian influenza H5N1 viruses?

题名: 由人流感病毒N1神经氨酸苷酶引发的免疫性对禽流感病毒H5N1亚型能否起到防护作用?


Keywords Avian influenza;H5 subtype;H9 subtype;Non-essential region;Recombinant fowlpox virus;Hemagglutinin;Neuraminidase;Genetic stability;Maternal antibody;Protective efficacy;

鸡痘病毒载体;复制非必需区;H5亚型禽流感;H9亚型禽流感;血凝素;神经氨酸酶;母源抗体;免疫效力;