liposome单词基本解析:
n.脂质体n. [生]脂质体
n.脂质体;
liposome变化用词:
liposome英英释义:
Noun1. an artificially made microscopic vesicle into which nucleic acids can be packaged; used in molecular biology as a transducing vector
名词 liposome:
an artificially made microscopic vesicle into which nucleic acids can be packaged; used in molecular biology as a transducing vector
liposome[ 'lipəusəum, 'lai- ]n.an artificially made microscopic vesicle into which nucleic acids can be packaged; used in molecular biology as a transducing vector
liposome中文词源:
liposome用法和例句:
AIM : To study preparation of strychnine solid liposome.
目的: 探讨番木鳖碱固体脂质体的最佳制备方法.
OBJECTIVE To study the preparation of isoliquiritigenin liposome and its stability.
目的:制备异甘草素脂质体并考察其包封率及稳定性.
Obviously, many considerations are involved in developing a drug delivery system as a liposome.
显然, 发展类似的药物输送系统要考虑许多复杂的问题.
It was suggested that liposome is a promising carrier dermal drug delivery system.
在经皮给药系统中,脂质体是一种极具前途的给药载体.
To prepare clindamycin phosphate liposome, and to determine the entrapment efficiency and particle diameter of it.
目的制备克林霉素磷酸酯脂质体并测定包封率及粒径.
Aim: Prepare reconstituted liposome entraprment of Ricin ( RRL ) and study its toxicity.
目的: 制备重建型蓖麻蛋白脂质体 ( RRL ),并探讨其毒性作用.
OBJECTIVE To evaluate the quality of astragaloside liposome and determine its entrapment efficiency.
目的对黄芪皂苷脂质体进行质量评价,测定黄芪皂苷脂质体的包封率.
OBJECTIVE To study and improve the synthesis of liposome excipient phosphatidyl ethanolamine.
目的研究并改进脂质体辅料磷脂酰乙醇胺的合成工艺.
Results The top encapsulation percentage of Evans blue liposome is 25 30 %.
结果 伊文思蓝脂质体的包封率最高为2530%.
The antioxidant properties of five multimethoxyl flavonoids from citrus peel method and phospholipids peroxidantion in liposome.
通过体外抗氧化实验对柑橘皮中五种多甲氧基黄酮单体的抗氧化功能进行研究.
Thus, the tissue cell becomes a target of the highly specialized liposome.
这样, 组织细胞就变成了特制微脂粒的目标.
Aim To prepare amylopectin anchored dipyridamole ( DIP ) liposome and to study its tissue distribution in mice.
目的研究支链淀粉修饰双嘧达莫 ( DIP ) 脂质体的制备方法并考察其在小鼠体内的组织分布.
AIM Automatic measuring and quantitative analysis of form feature parameter of the liposome and emulsion image.
目的研究脂质体、乳剂图像的形态参数的自动测量与定量分析.
Azithromycin liposome was prepared with the granular soya lecithin by reverse evaporation method.
采用逆相蒸发法,利用大豆粉状磷脂制备阿奇霉素脂质体.
In order to maintain liposome stability and shelf life, several factors must be considered.
为了维持微脂粒的稳定性和寿命, 几个因素必须考虑.
Targeting therapy of liposomes should he well matched with the liposome behavior in vivo.
脂质体的靶向治疗应用与脂质体的体内生物学行为相一致.
OBJECTIVE To estimate drug penetration through skin using liposome electrokinetic chromatography.
目的采用脂质体电动色谱法对药物透皮吸收进行评估.
The liposome peroxidation, however , initiated by phenanthroline copper chelate was prerented by · OH scarvages and EDTA.
羟基清除剂及EDTA可抑制菲咯啉铜配合物介导的脂质体过氧化反应.
Objective To discuss the in vitro killing effect of injecting paclitaxel liposome on endometrial carcinoma.
目的探讨注射用紫杉醇脂质体对人子宫内膜癌细胞系的体外杀伤作用.
At the same time, some means about improving a special targeting of immune Liposome are offered.
同时提供了一些提高免疫脂质体特定靶向性的一些方法.
Amphotericin B in liposome revealed fine stability.
两性霉素B在脂质体中具有优良的稳定性.
liposome
HLF;sperm;liposome;glandmammary special expression vectors;transgenic animals.
01人乳铁蛋白;精子;脂质体;乳腺特异表达载体;转基因动物
5-Fluorouracil magnetic liposome nanoparticle(MNLF)
5-氟尿嘧啶磁性纳米脂质体
The drug concentration of DPPC liposome is highest, it had a drug pinnacle descending slowly, and kept a high concentration level during a long time, the drug resorted in skin was most.
DPPC脂质体药物浓度最高,它能使药物浓度很快达到高峰,然后缓慢下降,长时间内维持一个高的浓度水平,使药物在皮肤内的滞留量最大,时间最长。
DSPE PEG, Tween80, and Brij35 have slight effect on the encapsulation percentage of Evans blue liposome.
DSPE PEG、Tween80和Brij35对伊文思蓝脂质体的包封率影响较小。
The relative targeting DDI of DSP lyophilized liposome capsule was 29.18 or 2.28, against DSP solution or DSP powder capsule, respectively.
DSP壳聚糖胶囊结肠DDI分别是DSP溶液的2918和DSP壳聚糖胶囊的228。
The difference was significant between siRNA+ASO2 group and siRNA group (all P<0.05). No significant difference was observed between siRNA+ASO1 group and siRNA group, neither between blank control group and liposome group (all P>0.05).
siRNA组与siRNA+ASO1组比较,细胞对ECM的粘附与侵袭力差异均无统计学意义,而siRNA+ASO2组细胞对ECM的粘附与侵袭力较siRNA组降低(P均<0.05)。
TNA may enhance transfection rate of plasmid DNA mediated with liposome, and may be beneficial to the treatment of cancer.
TNA可促进脂质体介导质粒DNA转染结直肠癌细胞 ,将营养支持与基因治疗相结合 ,有望提高对肿瘤患者支持治疗效果。
A method for producing a new type of liposome
一种新型脂质体的制作方法
Study on Tetracaine liposome Gel
丁卡因脂质体凝胶剂的研究
Compared with SOD solution, SOD liposome could rise the drug concentration and lower the lipid peroxide concentration in the tissues, and brain, blood and kidney showed signficant effects.
与SOD溶液相比,前者可提高各组织中SOD的含量,并降低脂质过氧化物水平,以血、脑、肾等最为显著。
Ingredients: Wheat germ, glycosphingolipid, eyeseryl, complex vitamin liposome, HA etc.
主要成份:小麦胚芽、鞘糖、乙酰丁肽-5、复合维他命脂质体、透明质酸等。
Ingredients: Liquorices extract, mulberry extract, compound vitamin liposome, HA, etc.
主要成份:甘草提取液、桑树提取液、复合维他命脂质体、透明质酸等。
Ingredients: Pea peptide, allantoin, compound vitamin liposome, HA, etc.
主要成份:碗豆肽、尿囊素、复合维他命脂质体、透明质酸等。
The applicantion of nanoparticles, liposome used as novel kinds of targeting drugs delivery systems were introduced in the text, and discussed the development of drug delivery system in the future.
介绍了纳米粒子、脂质体和植入剂等新型药物载体的应用,并就药物载体的发展方向进行了探讨。
Liposome technology and its recent proceeding of research and application in food industry were introduced.
介绍了脂质体技术及其在食品工业中的最新研究进展与应用情况。
The application and development of modifying liposome with fortified material to improve hepatic targeting effects was reviewed.
介绍强化材料修饰脂质体以提高肝靶向性的应用及发展状况。
Survivin WT and Survivin T34A could obviously express in A549 tumors after transfected with liposome.
以脂质体为载体转染survivin WT和Survivin T34A在A549肿瘤中可明显表达。
The top encapsulation percentage of Evans blue liposome is 25 30%.
伊文思蓝脂质体的包封率最高为 2 5 30%。
The liposome appears good biocompatibility, slow-releasing potential and targeting property after chemical or physical modification and improvement.
传统脂质体经修饰和改良后表现出良好的生物相容性,缓释性和靶向性。
He described the technique to put this gene inside plasmid cationic liposome complexes and then deliver it intravenously.
先将环氧合酶基因导入质粒阳离子脂质体复合物,再通过静脉给入。
There are slight differences of content ,the entrapment efficiency and accelerated test between liposome and proliposome.
冻干前后脂质体的含量和包封率变化不大,离心加速试验的结果也没有明显区别。
Using liposome as a carrier to effectively transport vitamin A &E to the dermis, accelerate the production of skin protein and prevent dryness and aging of skin.
利用磷脂囊传送载体将维他命A及E直达真皮层,加速表皮蛋白的产生,可预防皮肤乾燥、老化及延缓细纹的产生。
The SOD of liposome is more stable than free SOD while imposed pepsin or at high temperature.
包封后的SOD在胃蛋白酶的作用及高温下,比游离的SOD稳定。
The main artery and kidney was kept enhancing for 1 hour after 100 nm BFVs liposome was injected in ear vein of the rabbits.
包封率为69±5.4%,远高于其它类型脂质体,100nmIFVs脂质体经兔耳静脉缓慢注射后大动脉及肾脏得以持续强化,长达1小时左右。
Keywords pilocarpine;liposome;miotic;pupil;
匹罗卡品;脂质体;缩瞳药;瞳孔;
unilamellar compartment liposome
单室脂质体
At the same time, some means about improving a special targetting of immune Liposome are offered.
同时提供了一些提高免疫脂质体特定靶向性的一些方法。
The pharmacokinetics of the liposome after intravenous injection was studied.
同时考察包合物脂质体的体内药物动力学性质。
Therefore,drug release and duration of liposome target sites are analyzed so that people can find out those potential target sites for rational targeted delivery.
因此,对脂质体体内靶向部位的药物控释和持续时间等方面进行研究,从而寻找到体内那些合理的靶向部位。
Immobilized liposome chromatagraphy
固定化脂质体色谱
immobilized liposome chromatography ( ILC )
固定脂质体色谱
Encapsulation with liposome DDAB/EPC has the strongest adjuvant effect in inducing Th1 dominated immunity. Alum and Montanide can convert the Th1 nature of DNA vaccine to Th2-biased immunity.
在4种佐剂中,DDAB/EPC效果最好,Montanide和氢氧化铝可将DNA疫苗Th1为主的免疫特性转换为以Th2为主。
The dual-ligand formulations are therefore likely to be heterogeneous in the actual number of ligands per liposome.
在每个脂质体实际的配体数目中,双倍配体模式可能是不均一的。
It was suggested that liposome is a promising carrier for trans dermal drug delivery system.
在经皮给药系统中,脂质体是一种极具前途的给药载体。
Keywords uniform design;taspine;liposome;
均匀设计;塔斯品碱;脂质体;
Multivesicular liposome(DepoFoam)
多室脂质体
Keywords Emodin;Magnetism;Nanometer Liposome;
大黄素;磁性;纳米脂质体;
The interaction of linoleic platinum targeted liposome with tumor cell membranes has been investigated by mothod of MSL spin Labeling.
实验发现,无论在动物存活数、肿瘤发生率还是在肿瘤生长速度方面,亚油酸铂靶向脂质体的抑制能力都明显在优于游离亚油酸钠。
The results indicated that the livers and spleens level of the liposome are higher than thoseof the praziquantel, and that the t_(1/2) of the former is prolonged.
实验结果表明,吡喹酮脂质体较游离吡喹酮在小鼠肝、脾组织内药物总含量明显增高,半衰期延长。
Keywords ONDs;transfection;cationic liposome;
寡核苷酸;转染;阳离子脂质体;
Physical stability of dipalmitoyl cyclocytidine(DPCC) liposome was evaluated.
对环胞苷二棕榈酸酯脂质体的物理稳定性进行了评价。
Freeze-drying liposomes were prepared and the effect of different cryoprotectant on the appearance and reconstruction of freeze-drying liposome were evaluated.
将所得脂质体进行冻干,考察不同支撑剂对冻干脂质体形态及复溶效果的影响;
liposome of small molecular RNAi
小分子干扰核糖核酸脂质体
The distribution in mouse of praziquantel and it's liposome has been studied by the auth-ors using RP-HPLC.
应用RP-HPLC法测定吡喹酮及其脂质体在小鼠体内的分布。
An Experimental Study of Photodynamic Effect of Hypocrelline B Liposome on Leghorn Cock Comb[J].
引用该论文 刘慧龙,刘凡光,顾瑛,马江华,赵井泉,曾晶,李晓松.
The application of new liposome in DDS was explored.
探讨了新型脂质体在药物传递过程中的应用。
Study on the improvement of affinity of the liposome carried medicine.
提高载药脂质体亲和性的探讨。
Abstract Liposome capillary electrophoresis (LCE) is a recent approach and playing more important role in the separation and analysis process.
摘 要 脂质体毛细管电泳是近年新发展起来的一种分离分析技术。
Liposome capillary electrophoresis (LCE) was used as a model for the in vitro evaluation of the degree of membrane penetration of organic compounds.
摘要 有机化合物在脂质体毛细管电泳中的保留值大小可以体现化合物的亲脂性大小。
Objective: To investigate the activities of transdermal penetration of sinomenine liposome patch.
摘要 目的:研究青藤碱脂质体贴剂的经皮渗透行为。
Objective To introduce the progress of liposome entrapped cyclodextrin complex delivery systems.
摘要目的介绍环糊精包合物脂质体给药系统的研究进展。
Liposome has similar lipid bilayer structure and fluid characteristics to real cell membrane, and plays an important role in mimetic biomembrane research.
摘要脂质体具有与细胞膜相似的封闭双层结构,是接近天然生物膜的理想模型。
The application of liposome as a drug deliver system has become research hot topic at home and abroad.
摘要载药脂质体给药系统已成为国内外的研究热点。
Methods: Fourty male SD rats were randomly divided into four groups(n=10):normal control group(NC), hypoxia-hypercapnia group (HH), hypoxia-hypercapnia + L-arginine group(HL) and hypoxia-hypercapnia + L-arginine liposome group (HP).
方法 :将 4 0只健康雄性SD大鼠随机分为 4组 ,正常对照组 (NC组 ) ,低氧高二氧化碳 4周组 (HH组 ) ,低氧高二氧化碳加L Arg4周组 (HL组 )和低氧高二氧化碳加L Arg脂质体 4周组 (HP组 )。
Methods Neomycin gene was transfected into human embryonic fibroblasts (HEF) by liposome mediated method. Using this transfected HEF as feeder layer, ES cells were transfected with AANAT gene.
方法 将外源性neo基因转染人胚胎成纤维细胞 ,作为饲养层细胞用于ES细胞转基因后筛选及增殖过程的培养。
Methods Liposome entrapped plasmid pDR2/tk was transferred into HCC cells, and then different concentrations of GCV or ACV were added into each well.
方法 设更昔洛韦(GCV)组、阿昔洛韦(ACV) 组和对照组共3 组,脂质体包裹质粒转染人肝癌细胞后分别加入不同浓度药物;
Methods: Immature rabbits were divided into 4 groups:control,BLM,liposome and trans-gene groups.
方法:1月龄幼兔分为对照组、BLM组、脂质体组和转基因组。
Methods:The polycondensation of amino acids in liposome system as well as in aqueous buffer solution was started from amino acid-N-carboxyanhydrides(NCAs).
方法:活化氨基酸的聚合反应在囊泡体系和对照缓冲溶液中进行,反应产物用高效液相色谱-质谱联用仪进行分离检测。
METHODS: The study was performed by a randomized multicenter way. The trial group was administered with paclitaxel liposome (at a dose of 135mg/m+2) and cisplatin for 2 cycles (1 cycle=every 3 weeks).
方法:采用多中心随机入组的方法进行研究,试验组给紫杉醇脂质体每次剂量135mg/m2,联合使用顺铂,每3周为1周期,共2周期。
Method On the base of the single factor investigation,preparation conditions of tegafur liposome were optimized by uniform design.
方法在单因素考察的基础上,采用均匀设计法进行优化实验。
Methods BMGNeo-IFN-a DNA was transferred into NIH3T3 fibroblasts by the liposome method.
方法将人IFN-a基因体外转染成纤维细胞NIH3T3中,获得一株高分泌IFN-a的细胞克隆株NIH3T3-IFN-a+。
Methods The preparation methods, characteristics and the applications of liposome entrapped cyclodextrin complex in pharmaceutics were reviewed.
方法根据近年来的21篇文献资料进行归纳整理、分析评述。
MethodsThe rheological property of 0.1%,0.2% and 0.4% PC liposome eye drops was determined.The effects of different PC liposome eye drops on ophthalmoxerosis were investigated in rabbit models.
方法测定0.1%,0.2%和0.4%PC脂质体滴眼液的流变学性质,并通过建立兔眼干燥症模型,考察3种不同浓度的PC脂质体滴眼液的疗效。
Methods The theological property of 0. 1%, 0.2% and 0.4% PC liposome eye drops was determined.The effects of different PC liposome eye drops on ophthalmoxerosis were investigated in rabbit models.
方法测定0.1%,0.2%和0.4%PC脂质体滴眼液的流变学性质,并通过建立兔眼干燥症模型,考察3种不同浓度的PC脂质体滴眼液的疗效。
Methods Hep3B cells which lack the expression of both p53 and retinoblastoma tumor suppressor genes because of deletions, were transfected with a wild-type (wt) p53 cDNA and control vector by a liposome method.
方法通过采用脂质体介导转染技术,将野生型p53 cDNA导入一种p53和Rb基因缺失的肝癌细胞株Hep3B。
Methods: The sinomenine liposome patches and the same patches without liposome were used as model drugs.The transdermal penetration of the two patches was respectively tested in vitro and in vivo.
方法:以青藤碱脂质体贴剂与不含脂质体的普通贴剂为模型药物,分别采用离体和在体经皮渗透试验进行比较研究。
Being a reliable and safe way to reverse MDR, drug delivery systems (DDS) such as micelle, liposome and nanoparticle, represent a promising prospect both in research and application in recent years.
本文重点综述了药物传递系统中的聚合物胶束逆转多药耐药的研究结果及其可能的作用机制。
Mater i a Is and Methods Eukaryotic expression vector of EGFR antisense RNA, pLXSN-AE5? was transfected into SMMC-7721 by using Stearylamine/DOPE (SA liposome).
材料与方法:应用十八酰基胺阳离子脂质体(SA阳离子脂质体)将EGFR反义RNA真核表达载体pLXSN-AE5’导入SMMC-7721细胞中,G418抗性筛选出稳定克隆细胞。
The effects of DSPE PEG, Tween80, and Brij35 on the encapsulation percentage and tissue distribution of Evans blue liposome in the rat were determined.
比较了用DSPE PEG、Tween80和Brij35修饰后的伊文思蓝脂质体包封率和在大鼠体内分布状况的变化。
Beigi F,Gottschalk I,Lagerguist H,et al.Immobilized liposome and biomembrance partitioning chromatography of drugs for prediction of drug transport[J].Int J Pharm,1998,164(1 -2):129.
毛希琴,邹汉法,罗权舟,等.模拟生物膜色谱用于预测药物的小肠吸收[J].分析化学.2001,29(10):1135.
They are tumor cryosurgery,fracture prevention of the thoracic artery during cryopreservation,freeze drying of liposome,and microcapsulation of islet.
溶液冻结过程的显微图象;血管低温断裂及其防止;脂质体药物质的低温冷冻干燥;
The elimination half-life time of positive, negative and PBS was 51.52min, 14.75min and 4.18min respectively. The toxicity of ACV liposome preparation was investigated by using index of eye irritation experiments .
滞留能力正电性脂质体>负电性脂质体>空白缓冲液,半衰期t_(1/2)分别为51.52min,14.75min和4.18min。
temperature-sensitive polymer liposome
热敏高分子脂质体
However, freeze-drying process can induce serious and irreversible damage to liposome, including size increasing, membrane rupture, liposome infusion, membrane infolding, and the drug leakage etc.
然而,冷冻干燥技术可以引起严重的和不可逆的损伤,包括粒径的增加、膜的破裂、脂质体的渗漏、膜的折叠和药物的渗漏等等。
Keywords Rabies virus;Liposome vaccine;Property;
狂犬病毒;脂质体疫苗;性质;
The psoriatic change induced by propranolol hydroride was significantly suppressed by the CsA liposome cream.
环孢素A脂质体乳胶剂对豚鼠银屑病模型有效。
The vector pcDNA3.1-hVE GF165 was transfected into BMMSC with the method of liposome mediated. The expre ssion of human VEGF165 in the transfected cells was detected by RT-PCR,ELISA a nd Western blotting analysis.
用脂质体介导pcDNA3.1-hVEGF165转染BMMSC,观察转染后细胞形态和生长情况的变化,通过RT-PCR、Western和ELISA鉴定VEGF在细胞中的表达情况.
It is easy and feasible to use membrane-ultrasound method to make the magnetic nanometer liposome of emo-din , and the envelopment rate of emodin is to be further enhanced.
用薄膜-超声法制成大黄素磁性纳米脂质体简便易行,大黄素的包封率仍有待进一步的提高。
doxycycline hydrochloride liposome
盐酸多西环素脂质体
gel of doxycycline hydrochloride liposome
盐酸多西环素脂质体凝胶
用作名词(n.)Ganciclovir liposome was prepared by reverse evaporating method.
方法采用逆相蒸发法制备脂质体。
Objective Recent preparative methods of interferon liposome were reviewed.
目的介绍近年来干扰素脂质体的常用制备方法。