hepatotoxicity单词基本解析：

n.肝中毒; 肝毒性
肝中毒
n.肝中毒；肝毒性；

hepatotoxicity变化用词：

hepatotoxicity英英释义：

HepatotoxicityHepatotoxicity (from hepatic toxicity) implies chemical-driven liver damage.

以上来源于:Wikipedia

hepatotoxicity中文词源：

hepatotoxicity用法和例句：

hepatotoxicity

carbon tetrachloride (CCl4) hepatotoxicity

CCl4肝损伤

Protective function of L-carnitine against valproate-associated hepatotoxicity in infant rats and its mechanism

L-肉碱对幼鼠丙戊酸肝毒性的保护作用及其机理探讨

Experimental study on susceptibility of high risk factors related with hepatotoxicity of valproic acid

丙戊酸肝毒性高危因素易感性机制的实验研究

Morphological observation of the valproate hepatotoxicity in rat's primary cultured hepatocyte

丙戊酸钠对大鼠肝细胞毒性作用的形态学观察

Keywords tussah colloidal solution;ethanol;hepatotoxicity;

丝胶;乙醇;肝中毒;

Andre J Scheen,Hepatotoxicity with Thiazlidinediones,Is it a Class Effect?

严敏、李少丽、吴晔,等.药品上市后再评价工作的现状与思考.中国新药杂志,1999;

Abstract: Objective: To compare the influence of different Bupleurun chinense composition to the degree of hepatotoxicity damage to rats and oxidative damage mechanism.

中文摘要: 目的：比较柴胡不同组分对大鼠肝毒性损伤程度和氧化损伤机制的影响。

Milk thistle has no major hepatotoxic effects, and N-acetylcysteine, an agent used to attenuate acetaminophen-mediated hepatotoxicity, is also unlikely to be a factor in his illness.

乳蓟无主要的肝毒性作用，N-乙酰半胱氨酸常用于中和对乙酰氨基酚引起的肝毒性作用，所以也不太可能是患者的致病因素。

Keywords metabonomics;nuclear magnetic resonance;pattern recognition;isoniazid;hepatotoxicity;

代谢组学;核磁共振技术;模式识别;异烟肼;肝毒性;

Keywords metabonomics;nuclear magnetic resonance（NMR）;pattern recognition;isoniazid;hepatotoxicity;

代谢组学;核磁共振（NMR）;模式识别;异烟肼;肝毒性;

In addition to lier abscesses and granulomata, drug hepatotoxicity is likely underappreciated. ascular lesions such as enopathy and--to a lesser extent--NRH are common.

但静脉病变的原因和临床意义有待进一步的评价。请按中英文对照格式发帖，以便其他战友浏览、纠错。嗯收到。以后注意新手学习。

Keywords total saponins from Panax notoginseng;hepatotoxicity;nephrotoxicity;rat;

关键词三七总皂苷;肝毒性;肾毒性;大鼠;

Keywords Carbon tetrachloride;Hepatotoxicity;Lipid peroxidation;Tiopronin;Mice;

关键词四氯化碳;肝毒性;脂质过氧化;凯西莱;小鼠;

Keywords Diagnosis;Drug induced liver injury;Hepatotoxicity;

关键词诊断;药物性肝损伤;肝毒性;

Keywords glutathione S-transferase serum acute hepatotoxicity;

关键词谷胱甘肽S一转移酶;血清;急性肝损害;

Keywords Ketoconazole;Primary cultured hepatocytes;Hepatotoxicity;

关键词酮康唑;原代培养肝细胞;肝毒性;

Test on hepatotoxicity of acetaminophen using gel entrapment culture of rat hepatocytes

凝胶包埋大鼠肝细胞用于醋氨酚肝毒性研究

Keywords Rifamycin sodium;Isoniazid;Rat;Hepatotoxicity;

利福霉素钠;异烟肼;小鼠;肝脏毒性;

anti - tumor agent hepatotoxicity

化疗药物性肝损害

Keywords Senecio;toxicity;hepatotoxicity;pyrrolizidine;alkaloid;adverse effect;

千里光;毒性;肝脏毒性;吡咯里西啶类生物碱;不良反应;

Studies on Rifampicin and Isoniazid-induced Hepatotoxicity Using in vitro Primary Hepatocytes

原代肝细胞体外培养用于利福平和异烟肼肝毒性的研究

EFFECT OF BICYCLOL ON ACETAMINOPHEN-INDUCED HEPATOTOXICITY: ENERGETIC METABOLISM AND MITOCHONDRIAL INJURY IN ACETAMINOPHEN-INTOXICATED MICE

双环醇对扑热息痛引起小鼠肝脏能量代谢和线粒体功能障碍的影响

Protective Effects of 2(3)-tert-butyl-4-hydroxyanisole against Hepatotoxicity Induced by Acetaminophen in Mice

叔丁基羟基茴香醚对小鼠醋氨酚中毒性肝损伤的保护作用

Pyrrolizidine alkaloids are activated by metabolic activation in liver and their parent compounds are converted into active “pyrrole” which may produce hepatotoxicity.

吡咯里西啶生物碱在肝脏代谢成活性代谢物吡咯后产生肝毒性。

Plants containing pyrrolizidine alkaloids were widely used in traditional medicine.Its hepatotoxicity is main toxicity as well known internationally.

含有吡咯里西啶生物碱的植物在传统医药中有广泛使用,其肝毒性引起广泛关注。

Keywords anisodamine;cyclosporine A;hepatotoxicity;prophylaxis;treatm

山莨菪碱;环孢素A;肝毒性;预防;治疗;

The Effect of Anisodamine on the CsA Hepatotoxicity and Clinical Study

山莨菪碱治疗环孢素肝毒性的机理及临床应用研究

The study on the susceptible gene of isoniazid and rifampicin-induced hepatotoxicity of pulmonary tuberculosis patients

异烟肼、利福平治疗肺结核致肝毒性易感基因的研究

The general investigation of the increased hepatotoxicity caused by isoniazid in combination with rifampin

异烟肼与利福平合用致肝毒性增加机制的研究概况

The potent toxin microcystin is frequently released during cyanobacterial blooms in eutrophic waters and show potent hepatotoxicity and tumor-promoting activity.

微囊藻毒素(Microcystin，MC)是水华蓝藻产生的一类环状七肽物质，是一种公认的肝毒素和促癌剂。

Keywords Microcystins;High performance liquid chromatography;Subchronic toxicity test;Hepatotoxicity;

微囊藻毒素;高效液相色谱;亚慢性染毒;肝毒性;

Keywords Cardiology;Amiodarone;Intravenous injection;Adverse reactions;Hepatotoxicity OR hepatic function abnormal;

心血管病学;胺碘酮;静脉注射;不良反应;肝功能异常;

acute hepatotoxicity

急性肝损害

Iessened the hepatic injury,These results suggest that sodium ferulate protect mice from CCl_4-induced hepatotoxicity and that the protective mechanism have something to do with inhibiting lipid peroxidation of celt mem- branes.

提示当归素能对抗 CCl_4肝损害,其抗肝损害机理与抑制膜脂质过氧化有关。

In traditional methods, hepatocytes can not be cultured with high viability and high density in vitro which restrict the evaluation of drug-induced hepatotoxicity in vitro.

摘要 传统的细胞培养方法中，肝细胞在体外不能实现高活性高密度的生长，因而无法模拟体内的三维立体生长环境，从而制约了药物肝毒性的体外评价；

Pyrrolizidine alkaloids are a large class of natural products with hepatotoxicity and have been identified in more than 6 000 plant species.

摘要 吡咯里西啶生物碱广泛分布于6 000多种高等植物中，是一类肝毒性很强的天然产物。

AIM To clarify whether ketoconazole has protective effects against or harmful influences on cocaine-induced hepatotoxicity in mice.

摘要 目的 澄清酮康唑对可卡因所致小鼠肝脏损伤具有有害的还是有益的影响。

Dimethylformamide(DMF), a widely used industrial solvent, has been reported to induce subtle to clinically overt hepatotoxicity.

摘要二甲基甲醯胺为工业上被广泛使用之有机溶剂。

Literature study indicates that tripterygium glycosides could not only treat liver diseases,but also lead to hepatotoxicity.

文献研究表明,雷公藤多苷既可治疗肝脏疾病,又能引起肝脏毒性。

METHODS Animal experimental models of hepatotoxicity induced by cocaine were applied to investigate the preventive and theropeutical effects, respectively.

方法 采用可卡因致小鼠肝损伤模型，分别使用预防性和治疗性给药两种实验方法。

This review introduces the development of micro-hollow fiber bioreactor combined with gel entrapment technique and its application in the field of hepatotoxicity evaluation.

本文综述了微型中空纤维凝胶包埋技术的发展及其在体外药物肝毒性方面的应用。

The postoperative complications included cyclosporine A hepatotoxicity, urinary fistula, acute tubular necrosis, leukopenia, and so on.

术后并发症有环孢素A肝毒性、尿瘘、急性肾小管坏死、白细胞减少等。

Ge L, Nnane I P, Cheng T Y. The effects of pretreatment with glycyrrhizin and glycyrrhetinic acid on the retrorsine-induced hepatotoxicity in rats [J]. Toxicon 1999,37:1259.

李慧超李凤霞等.高效液相色谱法测定野生甘草及栽培甘草中甘草酸的含量[J].中国药事,:.

Keywords Gardenia jasminoides Ellis;geniposide;hepatotoxicity;rat;mouse;

栀子;京尼平苷;肝毒性;大鼠;小鼠;

Moreover, antiretroviral therapy used to suppress HIV replication is often associated with a paradoxical increase in HCV RNA levels, as well as hepatotoxicity.

此外，抗逆转录病毒治疗用于抑制HIV复制通常与HCV RNA反常升高和肝中毒相关。

Erigeron Injections Effects on Pathologic and Hepatotoxicity Induced By Intestinal Ischemia-Reperfusion in Mice.

灯盏花注射液对肝损伤病理及生化指标的影响。

"However, hepatotoxicity is not a leading cause.

然而，肝脏毒性却不是最常见的原因。

Ursodeoxycholic acid is a kind of hydrophilic bile acid.It can hinder hydrophobic bile acid from its hepatotoxicity to liver and the damage of cytotoxic T lymphocyte(CTL) to its target cells.

熊去氧胆酸是一种亲水性胆汁酸,能阻止疏水性胆汁酸的细胞毒作用,抑制细胞毒T细胞(CTL)对靶细胞的攻击作用。

Tyson CA，Correlation of in vitro and vivo hepatotoxicity for five haloalkanes．Toxicol Apl Pharmacol．1983,70:289.

王尔华，等.分子连接性及其在定量构效关系中的应用.国外医学药学分册，1979，6(3)：129.

Keywords Cyclosporine;Drug concentration in blood;Hepatotoxicity;

环孢素;血药浓度;肝毒性;

Keywords cyclophosphamide（CP）;hepatotoxicity;oxidative stress;mitochondrial;voltage-dependent anion channel（VDAC）;

环磷酰胺;肝损伤;氧化应激;线粒体;电压依赖性阴离子通道;

The mechanisms involved in HAART-derived hepatotoxicity are not well understood.

目前，HAART导致肝毒性的机理尚不清楚。

AIM To study the effect of antihepatitis drug, dimethyl diphenyl bicarboxylate (DDB) on the metabolism and hepatotoxicity of aflatoxin B 1 (AFB 1) in rats.

目的 研究抗肝炎药联苯双酯对大鼠黄曲霉毒素B1代谢和肝毒性的影响。

AIM To establish an acute model of THA induced hepatotoxicity in mice, and observe the effects of DDB on THA induced liver damage.

目的 观察联苯双酯 (DDB)对他克林 (THA)诱发小鼠肝损伤的保护作用。

Objective: To probe the hepatotoxicity of Dioscorea bulbifera alcohol extract with different polarity.

目的:探讨不同极性黄药子醇提物组分导致肝毒性的强弱。

AIM: To study the effect of new antihepatitis drug, bicyclol, on the metabolism and hepatotoxicity of aflatoxin B1 (AFB1) in rats.

目的:研究抗肝炎新药双环醇对大鼠黄曲霉毒素B_1(AFB_1)代谢和肝毒性的影响.

OBJECTIVE:To summarize the investigations of the increased hepatotoxicity caused by the combined action of isoniazid (INH) and rifampicin (RFP) .

目的:综述抗结核药异烟肼与利福平合用时肝毒性增加机制的研究概况。

Objective: To reveal the new recognition of drug-induced hepatotoxicity.

目的:药物诱发肝毒性的新认识。

Objective To analyze the recent five year's clinical data of acute drug-induced hepatotoxicity.

目的分析急性药物性肝病发生的类型、药物年龄分布概况。

Objective To study the pathogenesis of halothane hepatotoxicity.

目的探讨氟烷性肝炎的发病机理。

McNeill L, Allen M, Estrada C, et al; Pyrazinamide and rifampin vs isoniazid for the treatment of latent tuberculosis:improved completion rates but more hepatotoxicity [M];Chest; 2003

知网空间,护肝药在结核病治疗中的应用价值,护肝药,肝毒性,结核病,获益率

Attention should be paid to the hepatotoxicity of oral sulfonylureas.

磺酰脲类口服降糖药物的肝毒性应引起足够的重视。

RESULTS:Clinical investigations and animal studies have shown many different mechanisms of higher hepatotoxicity caused by the administered of INH and RFP.CO...

结果:临床研究及动物实验表明异烟肼与利福平二者合用时肝毒性增加有多种论述。

CONCLUSION Allicin can inhibit the acute liver injuries induced by cocaine, which suggests the remedial effect of allicin on cocaine-induced acute hepatotoxicity.

结论 大蒜素可抑制可卡因引起的急性肝损伤，对可卡因所致急性肝中毒可能具有一定的治疗作用。

CONCLUSIONS This observation suggested that ketoconazole have preferably protective effect against cocaine-induced hepatotoxicity in mice.

结论 酮康唑能对可卡因引起的急性肝脏损害有一定的保护作用。

Conclusion It is should pay more attention to he drug-induced hepatotoxicity harms when using medicines espially for the middle and elderly persons and using Chinese medicines.

结论急性药物性肝病常见，临床用药时注意肝损害的发生，特别是中药制剂应用时应谨慎。

Conclusion: The different B. chinense composition all can induce hepatotoxicity damage, and the channel of hepatic damage is related with the peroxidative damage mechanism.

结论：柴胡不同组分均可导致大鼠肝毒性损伤，其途径与过氧化损伤机制有关；

Analysis of drug-induced hepatotoxicity and FDA white papers

美国FDA药物肝毒性监测和管理文件简析

The results indicate that DDB protected rats against AFB 1 hepatotoxicity by increasing the detoxifying metabolism of AFB 1 in the liver.

联苯双酯可通过增加大鼠肝脏对AFB1代谢的解毒功能起到肝保护作用。

Hepatotoxicity is one of the most common adverse reactions during anti-tuberculosis treatment.

肝损害是抗结核药物治疗中最常见的毒副作用之一。

Hepatic effects: Potential for hepatotoxicity; AST/ALT elevations (?2 times baseline) and rarely hepatic failure have occurred; monitor aminotransferases prior to and during use.

肝效应：有肝中毒的可能；AST/ALT升高（基线的2倍），罕见肝功能衰竭；使用前和使用过程中监测转氨酶。

The relationship between Herbs with hepatotoxicity and its property and active components--Analysis of literature on hepatotoxicity of 55 kinds herbs

肝毒性中药及其与药性和有效成分的关系--对55种中药肝毒性文献资料的分析报告

The high incidence of hepatotoxicity (45.5%) might be related to concomitantly administered antiepileptic drugs and not to TMZ.

肝毒性有很高的发生率(45.5%)，可能与同时应用的抗癫痫药物有关而与替莫唑安无关。

Sesamin Powder Protects Against Acute Hepatotoxicity Induced by Alcohol in Mice

芝麻素散剂对乙醇引起小鼠急性肝损伤的影响

Benzbromarone can be used in patients with mild to moderate renal insufficiency on a named patient basis but carries a small risk of hepatotoxicity.

苯溴马龙能用于轻中度肾功能不全的患者，但有引起肝毒性的轻度危险性。

drug-induced hepatotoxicity

药物肝毒性

Keywords drug-induced hepatotoxicity;drug related liver injury;drug safety;pharmacovigilance;

药物肝毒性;药物肝损害;药物安全;药物警戒;

Although the mechanism of alcohol hepatotoxicity has been well elucidated, the molecular mechanism by which alcohol induced cardiomyopathy is still unclear.

虽然酒精肝脏毒性机制已确切，但酒精所引起心肌病变之机制仍未清楚。

These results imply that the increase in APAP hepatotoxicity by oral administration of HSE is attributed to the increased oxidative stress.

这些结果暗示元宝草粗萃物经由促进体内氧化压力，而增强了肝肾毒性的可能性较低。

Discussions in this paper could be considered for future improvement of Chinese regulatory policy related to hepatotoxicity.

通过简析这些文件，以期为我国药物肝毒性的监测和管理提供重要的借鉴作用。

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