germline是什么意思   germline怎么读

germline单词基本解析：

germline变化用词：

germline英英释义：

germline中文词源：

germline用法和例句：

germline

Keywords C57BL/6J mice;embryonic stem （ES） cell;ICR mice blastocysts;transmitting germline;

6J小鼠;胚胎干细胞;ICR小鼠囊胚;种系嵌合体;

Only SU-DHL-4, SU-DHL-5, PA-3 cell lines had germline configuration.

8392细胞系缺失5Kb片断,仅SU-DHL-4,SU-DHL-5,PA-3细胞系维持胚系结构.

Nine of the antibodies used the same germline gene, VH1-69, and appeared to share the same neutralizing mechanism.

9种抗体为相同的胚系基因-VH1-69，而且似乎有着中和机制相同。

Not only that, but either the father or mother also had the virus in the chromosomes, suggesting it was a so-called germline transmission -- passed on in egg or sperm.

不仅如此，他们的父亲或者母亲也被发现身体中的染色体整合进了病毒，这表明病毒可能是通过一种所谓的系感染进行传播，这种传播途径一般是靠卵细胞或者精子来实现。

AMPLIFICATION OF C-erbB_1 GERMLINE AND BM REPRODUCTION AND LEUKOMOGENESIS IN DIFFERENT ANEMIAS

不同贫血病时C-erbB_1胚系扩增与骨髓再生和白血病发生

The brilliance of this strategy from the transposon’s perspective is that it would be one of the best ways to secure its place in the germline of the new individual.

从转位子的角度来看，这个排列的巧妙之处在于，它是保护新个体生殖表面的最好方法之一。

Here, we show that removing the translational repressor Nanos from either GSCs or their precursors, the primordial germ cells (PGCs), causes both cell types to differentiate into germline cysts.

作者表明从GSC或者其前体原始生殖系细胞(PGCs)去除翻译抑制物Nanos将使两种细胞分化成生殖系包囊。

Keywords Gene mutation;achondroplasia;fibroblast growt h factor receptor 3;germline mosaicism;

关键词基因突变;先天性软骨发育不全;成纤维细胞生长因子受体3;生殖细胞嵌合;

Int. J. Dev. Biol.: Germ-plasm specification and germline development in the par

关键词：生殖细胞.福尔摩莎抗体.发育途径.演化机制.

Bioinformatics was applied to analyses of recombination patterns,somatic mutations and germline gene segments usage,and to prediction of epitopes recognized by CTL.

利用生物信息资源分析B ALLIgHV基因重排类型、胚系基因片段利用及体细胞突变情况 ,并预测CTL细胞识别的表位。

Full sequencing analysis for BRCA1 germline mutations was performed on blood specimens from all cases.

利用血液标本，我们还分析了所有病例BRCA1基因胚系突变的全部序列。

Germline BMPR1A Gene Mutation in Chinese Family of Hereditary Mixed Polyposis Syndrome

华人遗传性混合息肉病综合征BMPR1A基因种系突变检测

Germline LKB1 gene mutation screening in 4 Chinese Peutz-Jeghers syndrome pedigrees

国人黑斑息肉病LKB1基因胚系突变的检测

Germline mutations in the BRCA1 or BRCA2 tumour-suppressor genes are strong predictors of breast and/or ovarian cancer development.

在BRCA1或BRCA2肿瘤抑制基因的种系突变是乳腺癌和/或卵巢癌进展的强烈预测指标。

Introducing genes into the germline is illegal in Germany.

在德国，将基因导入种系细胞是违法的。

In Drosophila ovaries, germline stem cells (GSCs) divide asymmetrically to produce daughter GSCs and cystoblasts, the latter of which develop into germline cysts.

在果蝇卵巢，生殖系干细胞（GSCs）发生不对称分裂产生子代GSC和成包囊细胞，后者发育成生殖系包囊。

In some insects with meriostic ovarioles, maternal germ plasm is assembled during oogenesis and contains germline determinants that originated from the perinuclear nuage in the nurse cells.

在某些具有营养细胞型微卵管的昆虫当中，母系生殖浆在卵发育的过程形成，而且生殖浆内所含生殖细胞决定物质系来自于营养细胞的生殖云。

Throughout the cell cycle, centrosomes in germline stem cells (GSCs) are oriented within their niche and this ensures asymmetric division.

在细胞周期整个过程中，干细胞在微环境中确定中心体取向，决定了细胞的不对称分裂。

"In warmer climates annual metabolic activity is likely to be greater, so this will lead to more total cell divisions per year in the germline."

在较温暖的气候，每年新陈代谢活动可能更剧烈，所以，在生殖系上会产生出更多的细胞分裂"

Genomic instability involving structure alterations and epigenetic effect stems from germline and somatic mutation and related to genetic susceptibility of cancer.

基因组不稳定性与癌的遗传易感性相关,涉及基因组结构改变和表遗传效应,来源于胚系突变和体细胞突变。

Keywords familial adenomatous polyposis;adenomatous polyposis coli gene;denaturing high-performance liquid chromatography;protein truncation test;germline mutation;

家族性腺瘤样息肉病;结肠腺瘤病基因;变性高效液相色谱技术;蛋白截短检测技术;胚系突变;

Analysis of germline mutations in the APC gene in familial adenomatous polyposis patients

家族性腺瘤样息肉病中APC基因的胚系突变分析

Detection of Germline Mutations in the APC Gene with the Protein Truncation Test

应用蛋白截短技术检测APC基因胚系突变

Germline E-cadh erin mutations have been found in several familial cases of diffuse gastric canc er and frequent inactivating mutations have been identified for the E-cadherin gene (CDH1) in diffuse gastric cancers.

异型增生是一种常见的胃癌癌前病变,为了认识E-cadherin基因在散发性胃癌发展过程中的分子改变,我们对不同地区不同阶段的胃组织标本进行了E-cadherin基因突变的检测.

Woodbury D, Reynolds K, Black IB.Adult bone marrow stromal stem cells express germline, ectodermal, endodermal, and mesodermal genes prior to neurogenesis.J Neurosci Res 2002;69(6):908-17

徐如祥,戴宜武,姜晓丹,等.成年骨髓间质干细胞体外诱导分化神经细胞的研究[J].中华神经外科疾病研究杂志,2002,1(1):63-7

Those patients with tumors exhibiting microsatellite instability and/or lack of protein expression underwent MSH2/MLH1 germline testing.

患有肿瘤者，皆显现了微卫星不稳定的情况，或者在MSH2/MLH1生殖辔胞试验时，蛋白质无法表现；

So I think germline gene therapy is quite likely to become an important biomedical procedure in the future, but not in combating aging.

所以，我认为，生殖系基因疗法在将来可能成为一种重要的生物医学方法，但在与老化战斗中不是重要方法。

Objective] To determine bone morphogenetic protein receptor type 1A (BMPR1A) gene germline mutations in two Singapore Chinese families of hereditary mixed polyposis syndrome (HMPS).

探讨遗传性混合息肉病综合征华人家系中BMPR1A基因是否存在种系突变。

Objective To explore germline mutation frequencies and features of mismatch repaired gene MSH6 in persons with different kinds of colorectal cancer.

摘要目的了解错配修复基因MSH6在不同形式大肠癌人群中的种系突变频率及特征，提供真正的突变热点。

Methods STK 11 germline mutation was analysed by DNA sequencing in 18 unrelation patients with PJS.

方法 用 DNA直接测序方法 ,对 18个家系的 PJ综合征患者 STK1 1 基因 9个外显子进行研究。

Finally I should say a word about germline gene therapy.

最后，我应当提一句生殖系基因疗法。

Some ethicists worry, too, that germline genetic manipulation would give rise to a market in elective genetic enhancements.

有些伦理学家也担心，人为篡改种系基因将产生一个选择性基因遗传增强的市场。

This article reviews the genetic and molecular mechanisms that control the formation of germline cells and male gametophytes and their interactions with surrounding somatic cells in plant.

本文着重概述和讨论植物雄性生殖细胞和雄配子体发生及其与周边细胞互作遗传机制研究的最新进展。

Woodbury D.Reynolds K.Black IB Adult bone marrow stromal stem cells express germline,ectodermal,endodermal,and mesodermal genes prior to neurogenesis 2002

牛朝诗.李健.傅先明.汪业汉骨髓间质干细胞的分离培养及向神经细胞分化的研究[期刊论文]-立体定向和功能性神经外科杂志2004(2

germline stem cell

生殖干细胞

Keywords germline stem cell;proliferation;immortalization;haploid;Bovine;

生殖系干细胞;增殖;永生化;单倍体;牛;

germline gene therapy

生殖细胞基因治疗

germline theory

生殖细胞遗传学说, 胚系学说:解释抗体多样性的学说之一

MSH6 germline mutation frequencies in male and female colorectal cancer were 4.49% and 7.00%, respectively.

男性、女性大肠癌患者MsH6种系突变频率4.49%、7.00%。

Advances in Male Germline Stem Cell

男性生殖干细胞工程

Production of avian germline chimeras and their application

禽类生殖嵌合体的制作及其应用

germline, germ line

种系

germline body

种系体

They were "tagged" with a genetic marker which enabled the scientists to identify and separate so-called "germline" stem cells from which eggs and sperm are developed.

科学家对这些细胞进行了基因标记，以便于辨认，被区分其他那些卵子和镜子发育而成的“胚胎”干细胞。

The Third Class Small RNA and Development of Germline

第三类小RNA和生殖细胞发育

" The second study showed that immunostaining or microsatellite instability are equivalent for determining who should be further screened for MSH2/MLH1 germline mutations.

第二项研究指出，在MSH2/MLH1生殖辔胞突变筛检前，免疫染色及微卫星不稳定性，两种检测法具有相同的重要性。

Keywords colorectal neoplasms;MSH6;germline mutation;

结直肠肿瘤;MSH6;种系突变;

Instead, every time a germline stem cell divides by meiosis to make sperm in adults the jumping genes are activated only to be silenced soon thereafter.

而且在成体中生殖系干细胞产生精子的每一次减数分裂都伴随着跳跃基因的活化，而活化后很快就被沉默。

germline gene

胚系基因

germline mutation

胚系突变

Chimeras were made by injecting the ES cells into C57BL/6J blastocysts,and the germline compositions of the chimeras were detected by mating them with albino ICR mice.

通过囊胚显微注射法，将ES细胞注入C57BL/6J胚胎中，制作了嵌合体，并通过对嵌合体后代毛色的观察，判断了嵌合体生殖细胞的组成。

Germline E-cadherin gene mutation screening in familial gastric cancer kindreds

遗传性弥漫型胃癌上皮型钙黏素基因种系突变的检测

Keywords Hereditary diseases;Stomach neoplasms;Genes;Germline mutation;

遗传性疾病;胃肿瘤;基因;种系突变;

recombinational germline theory

重组种系学说

Mitochondrial DNA somatic mutations and germline variations in patients with esophageal cancer

食管癌线粒体DNA体细胞性突变与种系性变异