exon是什么意思   exon怎么读

英式:['eksɒn]    美式:['eksɒn]

exon单词基本解析:

外显子
n. 编码顺序, 外显子
释义外显子;

exon变化用词:


形容词: exonic |

exon英英释义:

Noun

1. sequence of a gene's DNA that transcribes into protein structures;

"exons are interspersed with introns"

名词 exon:

sequence of a gene's DNA that transcribes into protein structures

同义词:coding DNA

exon[ 'eksɔn ]n.sequence of a gene's DNA that transcribes into protein structures

"exons are interspersed with introns"

同义词:coding DNA

exon中文词源:

exon用法和例句:

Four gene polymorphisms were identified in exon 7. They were Gly 551 X ( GGC → GGT ), Arg 554 His ( CGT → CAT ), Gln 567 Arg ( CAA → CGA ) and Val 582 Ile ( GTC → ATC ).

同时在外显子7上发现4个位点的基因多态性,分别为Gly551X(GGC→GGT ) 、 Arg554His ( CGT→CAT ) 、 Gln567Arg ( CAA→CGA ) 和Val582Ile ( GTC→ATC ).

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That exon could not FORM chemical compounds was once believed by scientists.

科学家们曾经认为稀有气体不能形成化合物.

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It is a missense mutation in exon III.

它是位于外显子III的错义突变.

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How to use high throughput exon array to analysis different mRNA isoforms expression is very important.

如何利用表现序列晶片分析信息核糖核酸同型体的表现量,是相当重要的.

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Conclusion Exon rearrangement of parkin gene exists in Chinese patients with isolated EOP.

结论我国散发EOP患者存在parkin基因外显子重排突变.

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Objective To explore the mutation of RET exon 13 in sporadic medullary thyroid carcinoma.

目的研究散发型甲状腺髓样癌酪氨酸激酶受体基因(RET)第13外显子的突变情况.

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exon


C to G at 536 site of exon 7, and AA179CCT to CGT; A to G at 588 site of exon 7,and AA196CCA to CCG. The genotype is presumed to be JKb(222A)/JKb(536G).

2)Exon5:nt222C>A、AA74AAC(Asn)>AAA(Lys),Exon7:nt536C>G、AA179CCT(Pro)>CGT(Arg),Exon7:nt588A>G、AA196CCA(Pro)>CCG(Pro),推测基因型为JKb(222A)/JKb(536G);


Study on the Relationship between the Clinical Data of Type 2 Diabetes Mellitus and the Variation of Leptin Receptor Gene Exon

2型糖尿病各临床变量与瘦素受体基因变异的关系研究


No SNP was found in the fifth and the sixth exon of PIT-1 gene in these three breeds pigs, and one SNP was found in the fourth exon.

3个猪种PIT、-1基因的第五和第六外显子中均未发现SNP;


Detection Hot Spots and Sequence-Analyzing the Mutation of Exon Eight in Wilson Disease Gene in 45 Chinese People

45例国人Wilson病基因第8外显子突变热区检测和序列分析


PolymorphismAnalysis for Exon 2 of Melatonin Receptor 1a Gene in Four SheepBreeds by PCR-RFLP

4个绵羊品种褪黑激素受体1a基因第二外显子PCRR-FLP分析


Frequencies of genetypes at codon 52 of MBL Exon I in healthy chinese Hans nationality

52位基因频率调查


In all bladder cancers, 25.8% had mutations in exon 7, but no mutation in exon 1.No positive SSCP was found in the two exons of control group.

62例膀胱组织中,第7外显子突变为25.8%,第1外显子未发现突变,在对照组织中,未发现有指示突变的异常带型;


In about 80%(32/40) of protan and deutan the changing of exon 5 for RPG or GPG was discovered.

80%(32/40)的患者可检测到红或绿色觉基因第5个外显子部分的改变。


Study of structural polymorphism of bcl-6 gene non-coding exon and its protein expression in transitional cell carcinomas

bcl-6基因非编码区结构多态性及蛋白表达与移行上皮癌关系研究


The C-KIT gene Exon 9,11,13 does not seem to be an alternative pathway development in AA of the child because neither expression nor activating mutations of these Exons are found.

C-KIT基因Exon9、11、13表达与儿童再障发病关系不大,提示儿童再障的发病可能不是由于Exon9、11、13突变引起。


Two alleles of the COMT gene as a result of a G/A transition in the exon 4 can lead to different COMT enzymatic activities.

COMT是儿茶酚-O-甲基转移酶的编码基因,其第4外显子的一个G/A转换可产生不同活性的等位基因。


The GG geneotype of the CTLA-4 gene at position 49 in exon 1 plays an important role in GD patients accompanied with GO.

CTLA-4外显子1第 17密码子49位点 A/G 二态性 GG 基因表型可能是 GD 患者伴发突眼的重要因素。


DNA examination identified a missense mutation at nucleotide 134 of exon 5 of the SOD1 gene resulting in the aminoacid substitution serine-134-asparagine (S134N).

DNA检查确定了SOD1基因第5外显子的第134位核苷酸的错义突变,导致了第134位的氨基酸由丝氨酸替换为天冬酰胺酸。


Abnormal single strand bands were found in the amplified fra gments as well of exon 1of EDAgene in t he patients as well as their mothers,the carriers.

EDA致病基因(EDA1基因)外显子1的PCR产物经SSCP分析显示,患者及其携带者母亲出现异常单链条带。


HLA-DQ proteins are heterodimers of Alfa and beta chains, and beta chains are encoded by the HLA-DQB1 gene which is high polymorphic mainly in the second exon.

HLA- DQB1基因是编码人的HLA II类抗原DQ分子 p链的基因,具有高度的多态性。


Gene mutations in p53 gene exon 11 were identified in all samples,which had the same type and site.

p53基因外显子11在所有的被检测样本中均发现突变,而且突变的位点及突变的类型均相同。


The results of PCR-SSCP analysis showed that 2 out of 4 SPA with abnormal exon 8 of p53 gene.

PCR-SSCP分析显示,本研究的4例涎腺多形性腺瘤组织中,2例出现第8外显子异常电泳带; 1例出现第6外显子异常条带。


Observation on polymorphisms of RhD gene exon

RhD基因外显子多态性观察


Keywords RHD allele;RhD phenotype;exon;PCR-SSP;polymorphism;

RHD等位基因;RhD表型;外显子;聚合酶链反应-序列特异性引物;多态性;


Subsequent DNA sequencing showed that the gene fusion involved exon 7 of EWS and exon 8 of WT1 genes. The fusion gene contained KTS sequence.

RTPCR检测出EWSWT1融合性mRNA,测序结果显示由EWS基因的7号外显子与WT1基因的8号外显子融合所产生,融合性基因含有KTS序列。


There were the positive results of PCR SSCP in the exon 7 of p53 of BEAS TE, exon 8 of p53 of BEAS STE, and exon 1 of p16 of both exposed cells, but there were only the suspicious positive results showed in the exon 1 of both exposed cells.

SSCP结果阳性的有BEAS TE细胞p5 3第 7外显子 ,BEAS STE细胞p5 3第8外显子以及这二种细胞的p16基因第 1外显子 ; Ki ras基因第 1外显子的结果仅为可疑阳性。


SU-DHL-9 had homozygous deletion of p16 gene. Meanwhile, SU-DHL-1 and Daudi cell lines had mutation of the second exon of p16 gene. GAC in codon 30 mutated into AAC.

SU-DHL-9有p16基因的纯合缺失,而SU-DHL-1和Daudi细胞系有p16基因的第二外显子的突变,SU-DHL-1的测序结果为密码子30的GAC突变为AAC,密码子35的GCT突变为ACT,密码子40与41之间插入了一个C;


The relationship between the exon 4 gene polymorphism of TIM-1 and rheumatoid arthritis

TIM-1外显子4基因多态性与类风湿关节炎关系的研究


Sequence Variation of TYR Exon 1 and Origin of Pigs

TYR基因外显子1的序列变异与家猪的起源研究


UCP2 Exon 8 Ins/Del polymorphism is associated with REE/kg in OW/OB group.

UCP2Exon 8Ins/Del多态位点与超重 /肥胖者REE/kg有关 ,参与其超重 /肥胖程度的不同。


Exon 8 and exon 12 of WD gene

WD基因8、12号外显子


C/C genotype of XPC exon 15 may be one of the factors that affect the risk of developing ESCC in non-smoking population in the high incidence region of Hebei Province.

XPC基因第15外显子C/C基因型可能是影响河北省食管癌、贲门癌高发区磁县和涉县非吸烟人群ESCC发病风险的因素之一。


The overall genotype and allelotype distributions of XPC intron 9 PAT+/- and exon 15 A2920C in ESCC and GCA patients were not significantly different from that in healthy controls(P>0.05).

XPC基因第9内含子PAT+/-和第15外显子A2920C的基因型及等位基因型频率在ESCC患者组、GCA患者组和对照组之间,其总体分布均无显著性差异(P>0.05)。


In contrast to the transcripts of RTN1 and RTN2, RTN3-A1 shares some significant similarity with RTN4-A in exon structure, tissue distribution, and brain expression profile.

与RTN1、RTN2的各转录本相比,RTN3-A1与RTN4-A在外显子结构,组织分布及其在脑组织中的区域表达方面有很高的相似性。


Model-independent sib-pair linkage analyses and tests of association were performed to analyze the genetic effects of the exon 12 polymorphism.

个体模型同胞配对后,通过进行连锁分析和关联实验,来分析外显子12多态现象的遗传效应。


Keywords Chinese population Mannose-binding protein Exon 1 Gene sequence;

中国人;甘露糖结合蛋白;第1外显子;基因序列;


Exon polymorphism of human RHD gene

人RHD基因外显子多态性研究


The effect of skipping just one exon can be dramatic for an organism.

仅仅略过一段表现子,就可能对生物体造成显著的影响。


RNAs in which this intron was spliced were abundant and encoded the SPV 14 kDa protein (analogous to the B19 11 kDa protein), which initiated at an AUG in the exon preceding the third intron.

从第三个内含子之前的外显子的一个AUG开始,该内含子拼接形成丰度较高的RNA,编码SPV 14 kDa蛋白(类似于B19的11 kDa蛋白)。


A variant within exon 7 of eNOS gene: G to T conversionat nucleotide position 894 resulting in replacement of glutainicacid aspartic acide at condon 298 effects the stability of eNOSprotein and results in decreasing of NO produce.

位于eNOS基因外显子7上G894T突变导致其编码蛋白298位发生Glu/Asp的错义突变,该突变存在影响eNOS蛋白的稳定性,从而降低蛋白的催化活性。


Polymorphism of exon 10 of prolactin receptor gene and its relationship with prolificacy of Jining Grey goats

催乳素受体基因外显子10多态性及其与济宁青山羊高繁殖力关系的研究


leader exon

先导外显子


Detection of deletions of the DMD gene by reverse dot-blotting hybridization with the cloned exon probes

克隆外显子探针反向斑点杂交检测DMD基因缺失


Keywords DMD;BMD;gene;exon;multiplex-PCR;dystrophin;immunofluorescence technique;

关键词DMD;BMD;基因;外显子;多重PCR;抗肌营养不良蛋白;免疫荧光技术;


Keywords FHIT gene;carcinoma of colon;total RNA;exon;open reading frame;

关键词FHIT基因;结肠癌;总RNA;外显子;开放阅读框架;


The difference between them is that HCA90 contains a 108 bp additional exon, which belongs to Alu repeat sequences and is inserted between exon 10 and 11 of the HCA519 gene.

其中HCA90所特有的外显子序列长 10 8bp ,属Alu重复序列片段 ,插入于HCA5 19外显子 10和 11之间 ,原为HCA5 19内含子序列 .


Its exact exon sensitivity of 93%, compared with a previous best of 84%, translates into many thousands of exons correctly predicted by CONTRAST but missed by previous methods.

其确切外显子的灵敏度为93 % ,相对于以前的最好的84 % ,转化为几千个外显子,正确地预测相反的,但错过了,由以往的方法。


Splice donor site -- the junction between the end of an exon and the start of the downstream introns, commencing with the dinucleotide GT.

剪接提供位--位在表现子终端和下一个表现子之间的接合点,由GT核苷对起始.


Splice donor site -- the junction between the end of an exon and the start of the downstream introns commencing with the dinucleotide GT.

剪接提供位--位在表现子终端和下一个表现子之间的接合点由GT核苷对起始.


Splice donor site -- the junction between the end of an exon and the start of the downstream introns, commencing with the dinucleotide GT.

剪接提供位--位在表现子终端和下一个表现子之间的接合点,由GT核苷对起始.


There is polymorphism at 20 exon LEPR gene in children with obesity, which may affect the lipid metabolism and the fat distribution.

单纯型肥胖儿童瘦素受体基因第20外显子存在基因多态性的变化,且这种变化明显影响肥胖儿童的脂质代谢及体脂分布。


Effect of Polymorphisms of Exon 3 at GH Gene on Growth Traits in Nanjiang Huang Goats

南江黄羊GH基因外显子3多态性及其对生长性状的影响


Comparing nucleotide sequences of FSHR gene exon 10 for goat, sheep (Ovisaries L) and bovine (Bos Taurus), the maximal similarity and the minimal divergence was 99.3% and 3.4%, respectively.

和普通牛(Bostaurus)FSHR基因第10外显子序列同源性比较和聚类分析结果表明,山羊、普通牛和绵羊该部分序列的相似性最高为99.3%;


In this study, we have identified a novel alternative splicing isoform of the RTN gene family, RTN3-A1, which contains an additional 2.3-kb exon.

在本研究中,我们确认了RTN3基因的一个新的转录本,RTN3-A1。它包含了一个以前所发现的RTN3转录本所不具备的新的长2.3 kb的内含子。


The polyadenylation signal (pA) within the vector defines the final exon of the endogenous transcription unit.

在载体中,多聚腺苷酸信号限制到内源转录单位的最后一个外显子。


The intensity of the higher molecular weight band (which included exon 51) was correspondingly reduced.

在较高的分子量带的强度(包括外显子51)也相应减少。


There were two peculiar PCR amplification products ofexon32 (3 l4bp) and exon 33 (462bp) of NFl gene in all of the patients andcontrols.

均分别获得NF1基因32、33号外显子的PCR特异性扩增带。


The Exon Standard Oil Company develops the new high polymer alloy

埃克森美孚开发新型高分子合金


The correlation analysis indicated that CSFV antibody value from pigs with genotype CC of DQB exon 2 was higher that AA, AC, and AB with AB the lowest and IgG average value being 8.87, 7.72, 7.31 and 6.68, respectively.

基于DQB基因外显子2的CC、AA、AC及AB四种带型中,具CC带型的猪其血清中的猪瘟抗体效价高于其它三个组合,AB带型的最低,其抗体平均效价分别为8.87、7.72、7.31及6.68。


Exon 8 of ATP7 B gene

基因8号外显子


Results: A polymorphisms of exon 20 of PARP????1 gene was detected in 320 Han people by PCR????SSCP, no abnormal bands were observed from the analysis of PCR????SSCP in other exons.

基因检测能有效筛查基因突变携带者,可以为进一步鉴定该突变功能上的意义提供基础的分子遗传学资料,因而具有重要的意义。


Exon 2 codes for amino acids 28-82, which include the catalytically active residues and a cluster of amino acids which bind rings C, D, E, and F of the oligosaccharide substrate.

外显子2为氨基酸28-82编码,其包括催化中心的残基(Glu35和Asp53)和结合寡糖底物的一簇氨基酸。外显子2可能代表原始的糖苷酶。


Exon 3

外显子3


Exon 7 splicing mechanism stems from the loss of TRIM5 intron 6 within the first 3 'splice site of the G / T mutation.

外显子7剪接丢失机制源于TRIM5第6内含子内3’剪接位点的G/T突变。


Keywords exon;retinoic acid receptor;psoriasis vulgaris;

外显子;维甲酸受体;寻常型银屑病;


FRACTAL SCALING PROPERTY ANALYSIS OF EXON AND INTRON SEQUENCES

外显子与内含子序列的分形尺度参数可分性研究


exon theory

外显子学说


exon trapping method

外显子截留法


exon trapping system

外显子截留系统


exon amplification

外显子扩增


exon sliding

外显子滑动


exon connection

外显子连接


In multivariate analysis, the presence of EGFR deletion exon 19 or L858R EGFR mutations in adenocarcinoma patients predicted longer TTF.

多因素分析提示,EGFR外显子19缺失或L858R突变的腺癌患者,是影响治疗失败时间的有利因素(延长治疗失败时间)。


Detection of mutation at exon 15 of APC gene in gastric cancer with multiplex PCR and DNA sequencing

多重PCR和DNA测序技术检测胃癌APC基因15外显子突变


How to use high throughput exon array to analysis different mRNA isoforms expression is very important.

如何利用表现序列晶片分析信息核糖核酸同型体的表现量,是相当重要的。


If the male-specific exon is spliced in during the first round of editing, however, a nonfunctional mRNA results, which commits the fly's cells to the male-specific pathway.

如果雄性专有的表现子在头一次剪接过程中保留下来,形成的mRNA将不具有功能,这样果蝇细胞就会步上发育成雄性的路径。


1.It is a missense mutation in exon III.

它是位于外显子III的错义突变。


Difference study on sporadic Parkinson's disease and familial Parkinson's disease in exon 4 of Parkin gene

家族性与散发性帕金森病Parkin基因4号外显子突变的差异性研究


In the Piedmont cattle,the myotatin sequence contains a mis sense mutation in exon 3,resulting i n a substitution of tyrosine for an in variant cysteine in the mature region of the protein,which i s consistent with other reports previously.

对PCR扩增片段克隆、测序结果显示,2头皮埃蒙特牛均在编码序列938处发生G到A突变,使编码氨基酸由半胱氨酸变为酪氨酸,符合前人检测结果。


No ABCB4 gene exon 6 and exon 14 deletion and point mutation were detected by PCR and PCR-SSCP, respectively.

对所有外显子6及外显子14的PCR产物进行SSCP筛查,无异常发现。


The differences in exon 2 of MTNR1A gene between Small Tail Han sheep and Dorset sheep consisted of five nucleotide changes (C329T, G355T, C566T, C580A and A675G), and homology of nucleotide sequence was 99.4%.

小尾寒羊与多赛特羊MTNR1A基因外显子2的差异由5个变化的核苷酸(分别为C329T、G355T、C566T、C580A和A675G)组成,核苷酸同源性为99.4%。


Establishing the mutant of coding calcium binding fragment of the 13th exon of human thrombospondin-1 gene with polymerase chain reaction

应用聚合酶链反应技术构建人血小板反应素1基因第13外显子编码钙结合域突变体


Detection of HLA-B locus exon 4 variants by sequence-specific primers PCR in southern Chinese

应用顺序特异性引物聚合酶链反应检测华南人群HLA-B座位第4外显子变异


When a gene called Sex-lethal is expressed, a male-specific exon may be skipped during splicing, leading to the synthesis of a female-specific Sex-lethal protein.

当一段称为性别致死(sex-lethal)的基因转录出RNA时,雄果蝇专有的表现子可能在剪接过程中遭切除,最后产生雌果蝇专有的性别致死蛋白;


At the same day, Boeing, US telephoned telegram as well as Exon Standard Oil Company and so on downward.

当天,波音、美国电话电报以及埃克森美孚等下行。